Clinical trial Recruiting at 1 site Interventional Ages 18 and up Men only

Using male peer networks to improve HIV prevention engagement

Official title: Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention: A Large-scale Cluster Randomized Trial to Increase HIV Self-testing and PrEP Uptake Among Men in Eastern Zimbabwe

Run by University of Stellenbosch · NCT06370923 · Data updated 2026-11-12

This study is testing whether using male friends to share HIV self-testing kits can help men in Eastern Zimbabwe get better access to HIV prevention services like PrEP.

Quick facts

Study typeInterventional
Ages18 Years and up
SexMen only
Enrollment3591 (estimated)
SponsorUniversity of Stellenbosch
Academic / other
Locations1 site (Mutare, Manicaland Province)
StatusRecruiting
StartedOctober 21, 2024
Main results expectedMay 31, 2028
Study endsMay 31, 2028
Registry record updatedMay 4, 2025
Trial IDNCT06370923 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adult men residing in the Manicaland province of Zimbabwe.

Probably not a fit

Patients who are not residents of the study site or who do not engage with male peer networks may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to enhance engagement with HIV testing and prevention services among men in Sub Saharan Africa, particularly in Eastern Zimbabwe. It employs an implementation science approach to distribute HIV self-testing kits through male social networks, supported by phone-based assistance and improved risk perception. The study utilizes a cluster-randomized trial design, recruiting participants from existing village boundaries to assess the impact of peer distribution on the uptake of Pre-Exposure Prophylaxis (PrEP). The intervention is designed to address barriers to HIV prevention and testing in the target population.

Why it matters

Potential benefit: If successful, this approach could significantly increase HIV prevention and testing among men, ultimately reducing new infections.

How similar studies have gone: Previous studies have shown promise in using peer networks for health interventions, suggesting this approach could be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Resident in study site

Where it's running

  • BRTI - Manicaland Centre for Public Health Research
    Mutare, Manicaland Province, Zimbabwe
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.