Using male peer networks to improve HIV prevention engagement

Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention: A Large-scale Cluster Randomized Trial to Increase HIV Self-testing and PrEP Uptake Among Men in Eastern Zimbabwe

NA · University of Stellenbosch · NCT06370923

This study is testing whether using male friends to share HIV self-testing kits can help men in Eastern Zimbabwe get better access to HIV prevention services like PrEP.

Quick facts

PhaseNA
Study typeInterventional
Enrollment3591 (estimated)
Ages18 Years and up
SexMale
SponsorUniversity of Stellenbosch (other)
Locations1 site (Mutare, Manicaland Province)
Trial IDNCT06370923 on ClinicalTrials.gov

What this trial studies

This project aims to enhance engagement with HIV testing and prevention services among men in Sub Saharan Africa, particularly in Eastern Zimbabwe. It employs an implementation science approach to distribute HIV self-testing kits through male social networks, supported by phone-based assistance and improved risk perception. The study utilizes a cluster-randomized trial design, recruiting participants from existing village boundaries to assess the impact of peer distribution on the uptake of Pre-Exposure Prophylaxis (PrEP). The intervention is designed to address barriers to HIV prevention and testing in the target population.

Who should consider this trial

Good fit: Ideal candidates for this study are adult men residing in the Manicaland province of Zimbabwe.

Not a fit: Patients who are not residents of the study site or who do not engage with male peer networks may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly increase HIV prevention and testing among men, ultimately reducing new infections.

How similar studies have performed: Previous studies have shown promise in using peer networks for health interventions, suggesting this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Resident in study site

Where this trial is running

Mutare, Manicaland Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HIV Infections, HIV self test, HIV Pre Exposure Prophylaxis, Peer Networks

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.