SER Familia: A family program to reduce acculturative stress and build resilience in Latino immigrant families.
Official title: SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Families
Run by Duke University · NCT06627764 · Data updated 2026-11-12
This program tests whether a six-session, community health worker–delivered family intervention can lower acculturative stress and reduce risks for substance use, intimate partner violence, HIV, depression, and anxiety among first-generation Latino immigrant parents and their 12–17-year-old children.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 12 Years to 100 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Duke University Academic / other |
| Locations | 1 site (Durham, North Carolina) |
| Status | Recruiting |
| Started | June 30, 2025 |
| Main results expected | July 31, 2028 |
| Study ends | January 31, 2029 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT06627764 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are first-generation Hispanic/Latino parents or parental figures who speak English or Spanish, have a child aged 12–17, and can attend the six-session program locally in Durham, North Carolina.
✕Probably not a fit
Families planning to move within two years, non-Hispanic individuals, parents without a 12–17-year-old child, or those unable to attend local sessions are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
SER Familia is a six-session family-based intervention co-developed and delivered by community health workers to reduce acculturative stress, strengthen resilience, improve parent-child and family health, and connect families with community resources addressing social determinants of health. The intervention targets a syndemic cluster of substance abuse, intimate partner violence, HIV risk, depression, and anxiety among parents and youth. Investigators will measure changes in those outcomes and examine how individual, family, and community mechanisms related to acculturative stress and resilience mediate the program's effects. Participation is for Hispanic/Latino first-generation immigrant parents with a 12–17-year-old child who speak English and/or Spanish and are able to attend local sessions.
Why it matters
Potential benefit: If successful, SER Familia could reduce multiple related health risks by lowering acculturative stress, strengthening family relationships and resilience, and improving access to local supports.
How similar studies have gone: Community health worker–led and family-based interventions in Latino populations have shown promise for reducing acculturative stress and improving mental health or substance-use outcomes, but applying a single intervention to prevent a syndemic of substance abuse, IPV, HIV risk, and mental health is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Eligible participants must identify as Hispanic/Latino/a/x/e, * be a parent or parental figure with Latin descent * have a child (Youth) aged 12-17 * speak English and/or Spanish Exclusion Criteria: * Families planning to move within two years will be excluded
Where it's running
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Duke School of Nursing
Durham, North Carolina, United States Recruiting
Study contacts
- Study coordinator: Rosa Gonzalez-Guarda, PhD
- Email: rosa.gonzalez-guarda@duke.edu
- Phone: 9196132634
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.