Condition

Medication Adherence clinical trials and research

• 19Clinical trials
• 77NIH research projects
• 14Countries

Newest Medication Adherence clinical trials

All recruiting trials (19)

• Medication Collaboration for Dementia: A Feasibility Study

  This study tests a short, joint medication-management session for people 60+ with early dementia or mild cognitive impairment and their family caregivers to see if it’s workable and helps with taking medicines and beliefs about dementia and independence.

  Recruiting Northwestern University · Chicago, Illinois · NCT07742189

• Improving HIV treatment and well-being for young men who have sex with men in Ho Chi Minh City

  This project will follow 300 young men (ages 18–24) living with HIV in Ho Chi Minh City for one year to see which social, mental health, and care factors are linked to staying on ART and keeping the virus suppressed.

  Recruiting Center for Applied Research on Men and Community Health, Vietnam · Ho Chi Minh City · NCT07559266

• What personal, social, and access factors affect taking diabetes medicines

  This project will see if patients' knowledge, beliefs, family support, healthcare communication, and access problems influence how adults with diabetes take their medicines.

  Recruiting University of Malaya · Ambāla, Haryana · NCT07420634

• Fear of hypoglycemia in people with diabetes

  This study looks at how fear of low blood sugar affects how people with diabetes take their medications and manage their diet.

  Recruiting Bilecik Seyh Edebali Universitesi · Bilecik · NCT07329985

• AI-powered mobile app to support chemotherapy for breast cancer

  A mobile app in Arabic uses AI to help women undergoing chemotherapy see if it can improve symptom control and medication adherence compared with standard care.

  Recruiting University of Baghdad · Baghdad · NCT07273812

• Tailored program to help teens and young adults with cancer take their meds

  A tailored program is being tested to see if it helps adolescents and young adults with cancer take their oral medications more consistently than the standard approach.

  Recruiting at 2 sites Children's Hospital Medical Center, Cincinnati · Kansas City, Kansas and 3 other locations · NCT07223463

• Finalizing an adaptive phone-based support program to help teens take their medications

  This pilot will test an adaptive phone-based support program to help adolescents and young adults with chronic conditions take their daily oral medications.

  Recruiting Children's Hospital Los Angeles · Los Angeles, California · NCT07084155

• Improving long-term medication adherence for HIV treatment

  This study is testing whether daily text messages and rewards can help people starting HIV treatment stick to their medication plan over the long term.

  Recruiting Rand · Kampala · NCT06949774

• Mobile app using daily incentives and action plans to build blood-pressure medication habits

  This tests whether a smartphone app that gives daily incentives and/or action-planning prompts can help adults with hypertension who sometimes miss pills take their blood-pressure medication more regularly and control their blood pressure.

  Recruiting Arizona State University · Los Angeles, California · NCT06876233

• Using a pill sensor system to improve HIV treatment adherence

  This study is testing a new pill sensor system to see if it helps adults with HIV stick to their treatment better and improve their health.

  Recruiting Phase 2 University of California, Los Angeles · Los Angeles, California · NCT06480578

• Evaluation of a pharmacist-led medication management service

  This study is testing whether a pharmacist-led service can help people with Type 2 diabetes and high blood pressure use their medications better and improve their overall health.

  Recruiting at 8 sites The University of Hong Kong · Hong Kong and 7 other locations · NCT06273761

• Peer support program to improve health for women living with HIV

  This study tests a program that combines therapy, exercise, and support from peers to help women living with HIV stick to their medications and improve their overall health.

  Recruiting University of California, San Diego · San Diego, California · NCT06216600

• TelTex4BP: A mobile program to help adults with hypertension in Nepal

  A mobile text and phone-based program (TelTex4BP) helps adults with high blood pressure in Nepal take their medicines and adopt healthier habits to lower blood pressure.

  Recruiting at 2 sites Central Department of Public Health · Kathmandu, Bagmati and 1 other locations · NCT05979168

• Polypill approach to reduce vascular risk after stroke in Ghana

  This study tests whether taking a single daily Polycap polypill (blood-pressure meds, a statin, and aspirin) for two years helps stroke patients in Ghana reduce their risk of future vascular events compared with usual care.

  Recruiting at 2 sites Phase 3 Northern California Institute of Research and Education · Parakou and 3 other locations · NCT05963568

• A mobile game to help young people stick to their HIV prevention medication

  This study tests a mobile game called Viral Combat to see if it helps young people aged 15-34 stick to their HIV prevention medication better than a different game.

  Recruiting at 3 sites Rhode Island Hospital · Boston, Massachusetts and 2 other locations · NCT05762705

• Reducing psychological barriers to PrEP use during pregnancy and postpartum in Cape Town

  This project will test a brief cognitive-behavioral program to see if treating depression and posttraumatic stress helps pregnant and postpartum women in Cape Town stay on PrEP.

  Recruiting Boston University Charles River Campus · Boston, Massachusetts and 1 other locations · NCT05624931

• Improving medication adherence for heart failure patients with family support

  This study is testing whether getting family support can help heart failure patients take their medications as prescribed and improve their health.

  Recruiting The University of Tennessee, Knoxville · Lexington, Kentucky · NCT05548413

• Mobile app to improve medication adherence after hospital discharge

  This study is testing if a mobile app can help patients remember to take their medications correctly after leaving the hospital.

  Recruiting McGill University · Montreal, Quebec · NCT05371548

• Support program for young adults recovering from opioid use disorder

  This study is testing a new support program to help young adults aged 18-28 with opioid use disorder stick to their treatment and feel more engaged in their recovery.

  Recruiting Potomac Health Foundations · Baltimore, Maryland · NCT04173416

NIH-funded research (newest 40 of 77)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding why patients with blood cancers start and stick with oral cancer medicines

  A study to learn what helps or hinders Black patients with blood cancers in starting and continuing their prescribed oral cancer medicines.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11611692

• Incentives and Anchoring to Improve Long-term HIV Medication Adherence

  A study tests a simple, daily habit plan combined with friendly reminders and small rewards to help people living with HIV take their ART pills on time.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11590750

• WeCare: a combined mental health and HIV medication support program for high-risk men

  A patient-friendly program called WeCare aims to support mental health and improve adherence to HIV meds among high-risk men in settings with limited resources.

  NIH research Emory University · Atlanta, United States · NIH-11555368

• Medication adherence to epilepsy medicines during pregnancy and related birth outcomes

  This project looks at how well pregnant people with epilepsy take their anti-seizure medicines and what happens to their babies.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11454846

• Adaptive mHealth Support to Help Teens with Asthma Stick to Their Inhalers

  A multi-site study tests a flexible smartphone-based program to help adolescents with asthma take their inhaled meds more consistently.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11417160

• Reducing High Blood Pressure in Men in Manual Jobs with a Mobile Stress and Medication Adherence Program

  A mobile stress-management and medication adherence program aims to help men in manual and trade jobs lower their blood pressure and stay on their prescribed treatment.

  NIH research Isa Associates, INC. · Arlington, UNITED STATES · NIH-11408185

• Pharmacy-Integrated AI System to Help AD/ADRD Patients Take Meds and Stay Out of the Hospital

  A new AI-powered home medication system helps people with Alzheimer’s and related dementias take their medicines correctly to reduce hospital visits and ease caregiving.

  NIH research Hido Technologies, INC. · El Dorado Hills, United States · NIH-11406017

• Tailored adherence program to help adolescents and young adults with cancer take their medications

  A personalized program called SUMMIT helps teens and young adults with cancer take their prescribed medications more reliably to improve outcomes.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11401179

• WeCare: a mental health and HIV medication adherence program for high-risk men in resource-poor settings

  A patient-friendly approach called WeCare is being tested to help high-risk men manage stress and depression while sticking to HIV PrEP and ART in low-resource settings.

  NIH research Emory University · Atlanta, United States · NIH-11399084

• Medication adherence coaching for cancer patients guided by social cognitive theory

  A mentorship-based program in cancer care tests a coaching approach to help people take their cancer medications as prescribed.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11395579

• Mental health and HIV medication support for men in low-resource areas

  This project will try a combined mental-health and medication-support program to help high-risk men in resource-limited areas stay on HIV prevention and treatment.

  NIH research Emory University · Atlanta, United States · NIH-11383012

• Asthma and walking in older adults: brain signals, medicine use, and control

  This grant studies how asthma affects how older adults walk, looking at brain factors and how well they take their inhalers to understand mobility and health.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11382135

• Incentives and Anchoring to Improve Long-term HIV Medication Adherence

  A new approach uses habit-based anchoring with daily text reminders and small prizes to help people with HIV stick to their ART routines over time.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11381019

• Asthma Link: Partnering pediatric clinics, schools, and families to improve kids' asthma care

  A program that teams pediatric offices, schools, and families to help children with asthma take their daily controller medication at school and improve health outcomes.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11378966

• Incentives and reminders to help people take HIV medicines regularly

  This project uses daily reminders and small rewards to help people living with HIV keep a regular antiretroviral pill-taking routine.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11378660

• Improving how closely patients take their breast cancer medicines with a connected, personalized platform

  A randomized trial will test a text-message–based, personalized support system to help adult women with a certain kind of breast cancer take their prescribed CDK4/6 inhibitor medication more reliably.

  NIH research University of California-Irvine · Irvine, United States · NIH-11378178

• Pharmacist and community health worker team to help people with high blood pressure take their medicines

  A pharmacist paired with a community health worker will work with African-American, Latino, and Vietnamese patients who have high blood pressure and trouble taking multiple medicines to help them stick to their prescriptions.

  NIH research University of Arizona · Tucson, United States · NIH-11375260

• Medication support for children after a stem cell transplant

  This program gives caregivers short, tailored lessons and a Medication Management Kit to help families keep up with complex outpatient medicines after a child's allogeneic stem cell transplant.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11374322

• mCAT: a mobile habit-forming tool to help adults take blood pressure meds regularly

  A smartphone app-based program helps adults with hypertension, especially Medicaid enrollees, form lasting habits to take their blood pressure medications.

  NIH research Arizona State University-Tempe Campus · Scottsdale, United States · NIH-11348159

• PTSD, alcohol use, and HIV medication adherence in young adults

  A study following young adults with HIV or at risk for HIV to understand how PTSD and drinking affect taking HIV meds on time.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11324333

• Better communication and medication support for people with lupus

  This project trains clinicians and uses pharmacy refill records plus patient-reported barriers to help Black people with lupus take their medicines more reliably.

  NIH research Duke University · Durham, United States · NIH-11310777

• Pharmacy closures and how they affect older adults’ prescription use

  This project will look at how closing pharmacies affects whether older adults on Medicare Part D take their chronic medications.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11304512

• Pharmacy support to improve medicine use after hospital discharge for low-income adults

  This program offers pharmacy-led help—like free medications, bedside and home delivery, and coaching—to help low-income adults with chronic conditions take their medicines after leaving the hospital.

  NIH research University of Tennessee Health Sci Ctr · Memphis, United States · NIH-11290390

• Helping heart failure patients take their medications with family support and clear information

  This project helps patients with heart failure and their family members work together to make sure medications are taken correctly, aiming to improve health and prevent hospital stays.

  NIH research University of Tennessee Knoxville · Knoxville, United States · NIH-11269403

• Parenting skills to help young children take their medicines

  A parent-focused program designed to help families of children ages 3–9, including those with leukemia, improve how reliably kids take their medicines.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11251601

• Varenicline with nicotine lozenges and a phone support program to help adults quit smoking

  This project compares varenicline alone to varenicline plus nicotine lozenges and a smartphone medication-support program to help adults 21 and older stop smoking.

  NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11248834

• STEP-AD: empowerment and medication support for Black women living with HIV

  A 10-session program that combines trauma-informed therapy, adherence coaching, and empowerment skills to help Black women living with HIV take their medications and improve mental health.

  NIH research University of Miami Coral Gables · Coral Gables, United States · NIH-11245762

• Helping women with metastatic breast cancer take their medication as prescribed

  This project helps adult women with a specific type of metastatic breast cancer take their prescribed medication using a special mobile phone platform.

  NIH research University of California-Irvine · Irvine, United States · NIH-11190894

• AI-assisted video monitoring to help people with HIV take their medications

  This project uses an AI tool to check short smartphone videos so people with HIV can get support and reminders to take their daily medicines on time.

  NIH research University of Georgia · Athens, United States · NIH-11179364

• School-supported asthma medication program for children

  This program connects pediatric clinics, schools, and families so children with poorly controlled asthma can get their daily preventive medicine at school.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11177832

• Support for men's mental health and HIV medication use in low-resource settings

  This project pilots a program that combines mental health support with help taking HIV prevention and treatment medicines for high-risk men in low-resource settings.

  NIH research Emory University · Atlanta, United States · NIH-11172425

• Reminders and small rewards to help people with HIV take their HIV pills regularly

  This project uses daily reminders and small rewards to help people living with HIV take their antiretroviral pills regularly.

  NIH research Rand Corporation · Santa Monica, United States · NIH-11171473

• How asthma affects walking and the brain in older adults

  This project looks at whether asthma, asthma control, and how well people take their inhaled medicines relate to brain changes and walking ability in older adults.

  NIH research Albert Einstein College of Medicine · Bronx, United States · NIH-11167773

• Using a smartphone app to help people remember to take their blood pressure medication

  This study is looking at how a smartphone app can help people on Medicaid remember to take their blood pressure medicine by letting them earn rewards for showing they took their pills each day, making it easier to stick to their treatment plan.

  NIH research Arizona State University-Tempe Campus · Tempe, United States · NIH-11142518

• Pharmacist and Community Health Worker support to help people stick to blood pressure medicines

  This project aims to help African-American, Latino, and Vietnamese adults with high blood pressure take their medications more regularly by pairing pharmacists with community health workers.

  NIH research University of Arizona · Tucson, United States · NIH-11141694

• Improving medication adherence and reducing hypertension disparities through a pharmacist and community health worker team

  This study is testing a special program to help people with high blood pressure, especially in minority communities, stick to their medication by offering personalized support from a pharmacist and a community health worker who understand their unique needs.

  NIH research University of Arizona · Tucson, United States · NIH-11136613

• What helps people with blood cancers start and keep taking oral cancer medicines

  This project looks at why people with blood cancers (like CLL, CML, and multiple myeloma) do or don't start and stick with prescribed oral cancer medicines.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11136393

• Using technology to help young transplant recipients take their medications regularly

  This study is all about helping young people who have had kidney or liver transplants remember to take their medications by using smart pillboxes that track when they take their meds, so they can get support right when they need it to stay healthy.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11103311

• A mobile wallet intervention to improve tuberculosis care in rural Uganda

  This study is testing a new mobile wallet program to help people in rural Uganda get better access to tuberculosis care and stick to their medication by using text reminders and money for transport, making it easier for them to stay healthy.

  NIH research Mbarara University/science/ Technology · Mbarara, Uganda · NIH-11094062

• Improving Blood Pressure Control with Technology

  This project is exploring how mobile technology can help African American adults better manage their high blood pressure by taking their medications regularly.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11091590

Related topics

Quick answers

How many Medication Adherence clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (10 trials), South Africa (1 trial), Turkey (Türkiye) (1 trial), Nepal (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →