Improving HIV Screening and Prevention for Adolescents in Emergency Departments
Official title: Screen Smart: Using Digital Health to Improve HIV Screening and Prevention for Adolescents in the Emergency Department
Run by Children's Hospital Medical Center, Cincinnati · NCT06003192 · Data updated 2026-11-12
This study is trying out a new way to offer HIV testing and prevention services to teens aged 15-21 in emergency rooms to help keep them safe from HIV.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 21 Years |
| Sex | All |
| Enrollment | 63000 (estimated) |
| Sponsor | Children's Hospital Medical Center, Cincinnati Academic / other |
| Locations | 4 sites (Columbus, Ohio and 3 other locations) |
| Status | Recruiting |
| Started | December 16, 2024 |
| Main results expected | December 15, 2027 |
| Study ends | March 15, 2028 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT06003192 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adolescents aged 15-21 who are visiting a pediatric emergency department.
✕Probably not a fit
Patients who are critically ill, cognitively impaired, or unable to understand English may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to implement universal opt-out HIV testing and linkage to preventive care for adolescents aged 15-21 visiting pediatric emergency departments. It utilizes a tablet-based screening process to assess sexual health and identify candidates for HIV pre-exposure prophylaxis (PrEP). Participants will have the option to opt-out of testing and, if eligible, will be linked to PrEP services through a digital health platform. The research seeks to enhance the effectiveness of HIV screening and improve access to preventive care for at-risk youth.
Why it matters
Potential benefit: If successful, this approach could significantly increase HIV screening rates and access to preventive care for adolescents, ultimately reducing HIV infections in this population.
How similar studies have gone: Other studies have shown success with similar digital health approaches for screening and linking patients to care, indicating a promising avenue for improving HIV prevention efforts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients 15-21 years of age visiting a pediatric emergency department. Exclusion Criteria: * Unable to understand English * Critically ill * Cognitively impaired * Altered mental status
Where it's running
-
Nationwide Children's Hospital
Columbus, Ohio, United States Recruiting -
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States Not yet recruiting -
University of Utah
Salt Lake City, Utah, United States Not yet recruiting -
Children's Wisconsin
Milwaukee, Wisconsin, United States Not yet recruiting
Study contacts
- Principal investigator: Jennifer L Reed, MD, MS — Children's Hospital Medical Center, Cincinnati
- Study coordinator: Tricia Cobb, MS
- Email: patricia.cobb@cchmc.org
- Phone: 513-636-7966
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Screen2Prevent: HIV screening for teens and young adults in emergency departments
The study tests three ways of offering HIV screening to people aged 14–24 in emergency departments to see if it helps link them to PrEP or HIV treatment using digital health tools.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.