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Clinical trial Recruiting at 1 site Observational Ages 13 to 34

Exploring HIV risk in vulnerable youth with digital health intervention

Official title: Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention

Run by Hektoen Institute for Medical Research · NCT05848570 · Data updated 2026-11-12

This study is trying to see how a digital health program can help young sexual and gender minorities reduce their risk of HIV and understand the factors that affect their prevention choices.

More HIV Infections trials

Quick facts

Study typeObservational
Ages13 Years to 34 Years
SexAll
Enrollment6000 (estimated)
SponsorHektoen Institute for Medical Research
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedMarch 23, 2023
Main results expectedJanuary 2027
Study endsMay 2027
Registry record updatedMay 8, 2023
Trial IDNCT05848570 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include self-identified SGM adolescents aged 13-17 and young adults aged 18-34 who have engaged in sexual activity and are at risk for HIV.

Probably not a fit

Patients under age 13 or over age 34 will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the epidemiology and trajectories of HIV acquisition among adolescent and young adult sexual and gender minorities (SGM) in the United States. It will engage a diverse cohort of 6,000 sexually active SGM individuals aged 13-34 through a digital health platform, monitoring their HIV risk and prevention behaviors. The study will also explore socioecological factors influencing the use of new HIV prevention technologies and test novel digital health interventions. The approach combines longitudinal data collection with innovative digital health strategies to address rising HIV infection rates in this vulnerable population.

Why it matters

Potential benefit: If successful, this study could provide scalable and culturally appropriate HIV prevention interventions for at-risk youth.

How similar studies have gone: Other studies have shown success with similar digital health interventions targeting HIV prevention in at-risk populations.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* For young adults ages 18-34: self-identified SGM young adults ages 18-34 who meet at least one of the following criteria:

  * 1\) condomless anal or vaginal intercourse (CAI) with a cisgender man in the last 6 months OR
  * 2\) sex with cisgender men and bacterial STI in the last 6 months OR
  * 3\) anal or vaginal sex with a known HIV-infected partner in the last 6 months.
* For adolescents 13-17: self-identified SGM adolescents ages 13-17 who have engaged in any sexual activity (e.g., oral, anal or vaginal sex)

Exclusion Criteria:

* under age 13
* over age 34

Where it's running

  • John H. Stroger, Jr. Hospital of Cook County
    Chicago, Illinois, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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HIV Infections 98Sexual Behavior 14Hektoen Institute for Medical Research 3
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.