Motivational interviewing for male couples to reduce drug use and HIV risk

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

Not applicable Interventional Hunter College of City University of New York · NCT06307977

This study is testing whether a special conversation technique for male couples can help reduce drug use and lower the risk of HIV.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment360 (estimated)
Ages18 Years to 55 Years
SexMale
SponsorHunter College of City University of New York Academic / other
Locations3 sites (Detroit, Michigan and 2 other locations)
Trial IDNCT06307977 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of couples motivational interviewing (MI) in reducing illicit drug use and HIV transmission risk behaviors among male couples. Participants are randomly assigned to either receive couples MI or standard couples HIV testing and counseling. The study aims to assess changes in drug use frequency and HIV risk behaviors over time. By focusing on couples, the intervention seeks to leverage relationship dynamics to promote healthier behaviors.

Who should consider this trial

Good fit: Ideal candidates are male couples where one partner is HIV negative and both have a history of drug use and HIV risk behaviors.

Not a fit: Patients who are not in a male couple relationship or those without recent drug use or HIV risk behaviors may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly lower drug use and HIV transmission rates among vulnerable male couples.

How similar studies have performed: Other studies have shown promise in using motivational interviewing for substance use and HIV risk reduction, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have a main partner who is another cisgender male and have been in a relationship for 3 month or longer
* Index participant must be between 18 and 55; Main partner can be any age 18 and older
* One participant must be HIV negative (as confirmed by rapid test)
* One participant must have used at least 1 drug in the past 30 days (cocaine/crack, opiates, misuse of prescription medication, stimulants, psychedelics, ecstasy, ketamine, GHB, amyl nitrite)
* Index participant must have engaged in TRB in the past 30 days- Defined as CAS with a casual partner, or a serodiscordant or non-monogamous main partner
* Live in the United States
* Speak and read English

Exclusion Criteria

* Any signs of serious mental illness or cognitive deficit
* Current suicidal/homicidal ideations
* History of IPV with their main partner and safety concerns in the current relationship.

Where this trial is running

Detroit, Michigan and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Substance UseHIV Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.