Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Peer-driven intervention to prevent HIV, HCV, and drug overdoses among people who inject drugs

Official title: A Geospatial Analysis of Hotspots and Targeted Injection Settings Pilot Intervention for HIV Prevention Among People Who Inject Drugs in Baltimore, Maryland

Run by Johns Hopkins Bloomberg School of Public Health · NCT05320835 · Data updated 2026-11-12

This study is testing whether getting support and education from peers can help people who inject drugs reduce their risk of HIV, hepatitis C, and overdoses.

More HIV Infections trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment285 (estimated)
SponsorJohns Hopkins Bloomberg School of Public Health
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedApril 30, 2022
Main results expectedDecember 1, 2026
Study endsMay 30, 2027
Registry record updatedMay 22, 2026
Trial IDNCT05320835 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are current drug users, specifically those who have used opioids in the past two weeks.

Probably not a fit

Patients with any mental or physical health impairments that hinder their ability to participate may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot intervention focuses on reducing the transmission of HIV and hepatitis C virus, as well as overdose risk behaviors among people who inject drugs (PWID). Participants will be randomized into groups receiving peer education and access to risk reduction materials in semi-public injection settings, alongside standard care. The intervention is grounded in social influence and cognitive theories, aiming to enhance communication about risk behaviors and improve social norms. By increasing the availability of risk reduction materials and promoting peer outreach, the study seeks to reduce the sharing of injection equipment and improve naloxone access.

Why it matters

Potential benefit: If successful, this intervention could significantly lower the rates of HIV and HCV transmission and reduce overdose incidents among PWID.

How similar studies have gone: Previous studies have shown promise in using peer-driven interventions to address similar issues, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Current drug user (opioid use in the prior two weeks)

Exclusion Criteria:

* Any mental or physical health impairment that impedes ability to participate

Where it's running

  • Lighthouse Studies at Peer Point
    Baltimore, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Carl Latkin, PhD — Johns Hopkins Bloomberg School of Public Health
  • Study coordinator: Carl Latkin, PhD
  • Email: carl.latkin@jhu.edu
  • Phone: 410-955-3972

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.