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Clinical trials and research at The University of Texas Health Science Center, Houston

• 145Clinical trials
• 15Countries

Newest trials

All recruiting trials (145)

• Circadian Variation of Anti-Factor Xa in Trauma Patients on LMWH

  This study tests whether anti-Factor Xa levels show a daily rhythm in hospitalized trauma patients receiving LMWH for VTE prevention.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07856641

• PrioritiesAI: A chat tool to help older adults with hernia decide what matters most for surgery

  This study tests an AI-powered chat assistant to help people with hernia clearly express and communicate their health goals for elective surgery.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07848386

• Family-based program to reduce risk factors for schizophrenia spectrum disorders in youth with family history

  This study tests a brief family-based psychosocial program to see if it lowers persistent psychotic-like experiences in kids and young adults with a family history of SSD and different brain risk patterns.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07743645

• EUS-Guided RFA for Pancreatic Lesions: Safety and Outcomes

  This study tests whether using endoscopic ultrasound-guided radiofrequency ablation is safe and helps patients with pancreatic lesions.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07737171

• Skin-to-skin care with the Skincubator for preterm infants

  This study tests whether using the Skincubator during skin-to-skin care is safe and feasible for preterm babies and their parents in the NICU.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07721662

• See if iCHAMPSS 2.0 helps schools spread effective sexual health programs

  This study tests whether iCHAMPSS 2.0 helps Texas schools implement an evidence-based sexual health program more effectively for teachers, administrators, and health staff.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07679620

• Virtual reality-based cognitive and physical rehab for people with mild cognitive impairment or subjective cognitive decline

  This study tests whether VR-based cognitive and physical rehabilitation is feasible, usable, and acceptable for people with mild cognitive impairment or subjective cognitive decline.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07638748

• Culturally Tailored Exercise Program for Hispanics with Multiple Sclerosis

  A 16-week exercise program is being tested to see if it improves walking and quality of life for Hispanic adults with multiple sclerosis compared to a waitlist control.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07606742

• Improving School-Based Physical Activity for Cardiovascular Health in Kids

  A school-based program using MAGIC aims to see if enhanced active breaks, lessons, and motor activities can boost physical activity and cut cardiovascular risk factors among elementary students.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07541118

• Contingency Management with Deep TMS for Cocaine Use Disorder

  This study tests whether a combination of contingency management and deep TMS helps people with cocaine use disorder who haven’t responded to initial treatments.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07490600

• Multiple Sclerosis Implementation Network Registry

  This registry collects electronic health records and patient information to see if sharing data across clinics improves care and quality of life for people with multiple sclerosis.

  Recruiting at 3 sites The University of Texas Health Science Center, Houston · Cherry Hill, New Jersey and 2 other locations · NCT07415824

• vNOTE Hysterectomy with Uterosacral Suspension to Support Pelvic Organs

  This study tests a vaginal natural orifice surgery technique for hysterectomy that includes upfront uterosacral suspension to help prevent pelvic organ prolapse.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07413861

• Feasibility of paired non-invasive blood flow and tissue oxygen monitoring to detect limb ischemia during lithotomy-position surgeries

  This study tests whether using combined non-invasive blood flow monitoring and tissue oxygen sensors during long lithotomy surgeries can help detect early limb ischemia in adults.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT07387653

• Semaglutide microdosing for weight control in people living with HIV

  Small weekly doses of semaglutide will be tried to see if they prevent weight regain in adults living with HIV after an initial weight-loss induction.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT07325500

• Non-Invasive Brain Stimulation to Help Quit Smoking

  A new low intensity focused ultrasound treatment is being tested to help adults who smoke see if they can quit.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07298902

• Transcranial magnetic stimulation to reduce negative symptoms in schizophrenia-spectrum disorders

  This trial will test whether repetitive transcranial magnetic stimulation (rTMS) to the angular gyrus can reduce negative and other psychosis symptoms in adults with schizophrenia-spectrum disorders compared with prefrontal stimulation or sham.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07290738

• Home neuromodulation for bladder control after spinal cord injury

  This study tests home-delivered Injectrode tibial nerve stimulation to improve bladder function in people with chronic spinal cord injury.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07264868

• Culinary skills program for people in medication-assisted recovery living in recovery houses

  This project tests whether a cooking curriculum can improve nutrition knowledge and cooking confidence for people with substance use disorder receiving medication-assisted therapy who live in recovery residences in Texas.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07251205

• Semaglutide plus cognitive behavioral therapy for cocaine use disorder

  This trial will test whether adding semaglutide (a GLP-1 medication) to cognitive behavioral therapy helps adults with cocaine use disorder reduce craving and use.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT07227948

• Bispectral monitoring to guide sedation in mechanically ventilated ICU patients

  This study tests whether using BIS monitoring while patients are sedated on ventilators changes how long they stay on ventilation, ICU stay, and the total amount of sedation given.

  Recruiting The University of Texas Health Science Center, Houston · Cypress, Texas · NCT07219069

• Vibrant capsule treatment for neurogenic bowel in spinal cord injury

  This trial will test whether taking the Vibrant capsule is safe and helps bowel control in people with chronic spinal cord injury who have upper motor neuron neurogenic bowel.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07213986

• Temporary Clamping of Uterine and Ovarian Vessels During Minimally Invasive Myomectomy

  This study tests whether temporarily blocking blood flow from the uterine and ovarian arteries during minimally invasive myomectomy reduces blood loss for patients with large or multiple fibroids.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07182045

• Auricular point acupressure self-management for chronic musculoskeletal pain in rural communities

  This program will test whether a 4-week auricular point acupressure self-management approach (delivered via a smartphone app with remote training or with in-person training) helps adults in rural areas reduce chronic musculoskeletal pain and improve activity.

  Recruiting The University of Texas Health Science Center, Houston · Columbia, South Carolina and 2 other locations · NCT07179016

• Measuring phosphorylated tau‑217 (pTau217) in donated blood plasma

  This project will test donated blood plasma to see if some units contain high levels of phosphorylated tau‑217, a marker linked to Alzheimer's disease.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07157839

• At-home tibial nerve stimulation for children with spina bifida and neurogenic bladder

  This trial will try daily home transcutaneous tibial nerve stimulation for children with spina bifida and neurogenic bladder to see if it's safe, practical, and helps bladder control.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07136688

• Home-based brain stimulation plus intensive prolonged exposure for chronic pain and PTSD

  This trial will see if adding home-based transcranial direct current stimulation (tDCS) to an intensive, telemedicine-delivered prolonged exposure program helps people with chronic musculoskeletal pain and PTSD reduce symptoms and improve satisfaction compared with sham stimulation.

  Recruiting The University of Texas Health Science Center, Houston · Charleston, South Carolina and 1 other locations · NCT07116109

• Fintepla for Dravet Syndrome: testing brain blood flow and connections

  This study tests how Fintepla affects brain blood flow and network connections in Dravet syndrome patients who have convulsive seizures.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT07112365

• Vadadustat for nonintubated ARDS caused by infection

  This study tests if vadadustat can help hospitalized patients with nonintubated ARDS from infection breathe better and avoid needing a ventilator.

  Recruiting Phase 2/3 The University of Texas Health Science Center, Houston · Houston, Texas · NCT07086755

• Comparing quantitative and qualitative muscle-relaxant monitoring during non-cardiothoracic surgery

  This study will test whether using quantitative monitors instead of cheaper qualitative checks lowers oxygenation problems after non-cardiothoracic surgery in adults given rocuronium.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07084363

• Neurosensory account of anxiety and stress — experiment 2

  This trial tests whether a mild, noninvasive brain stimulation (tACS) tuned to each person's alpha rhythm can change brain activity and reduce anxious arousal and hypervigilance in adults with PTSD compared with sham and random-noise stimulation.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07079839

• Bilateral prefrontal and insular TMS to treat depression in schizophrenia.

  This trial will try repetitive transcranial magnetic stimulation (rTMS) with an H4 coil over both prefrontal and insular brain areas to see if it reduces depressive symptoms in adults with schizophrenia.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT07060066

• Evaluating CSF Flow in Premature Infants with Hydrocephalus

  This study is trying to see if a special dye can help doctors understand how cerebrospinal fluid flows in premature infants with hydrocephalus and if inflammation affects this flow.

  Recruiting Phase 1 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06994949

• Co-creating active middle school communities to boost student physical activity

  This project will try community-designed strategies to increase active transport and leisure physical activity for 6th-grade students and their families.

  Recruiting The University of Texas Health Science Center, Houston · Austin, Texas · NCT06970067

• Thalamocortical brain activity and noninvasive stimulation in chronic and pressure pain

  This research tests whether noninvasive brain stimulation (tACS or tRNS), measured with EEG and fMRI during tonic pressure pain, can change thalamocortical activity and alter pressure pain ratings in people with pain.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06968689

• Improving brain connectivity in schizophrenia using neuromodulation

  This study is testing whether a combination of brain stimulation and cognitive training can improve brain function and help people with schizophrenia feel better.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06961916

• Autologous umbilical cord patch for closing open spinal defects after birth

  This trial tests whether using a newborn's own umbilical cord tissue to close the dura can improve repair in babies born with open neural tube defects.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06929572

• Comparing two IV lipid infusions for very preterm or very low birth weight infants

  This study will try two types of intravenous lipid emulsions (mixed-oil vs soybean-oil) in extremely preterm or very low birth weight infants to see which better prevents bronchopulmonary dysplasia and supports growth and brain development.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06915441

• Depression treatment delivered through devices for adults with elder or self neglect

  This study tests whether a tablet/smartphone-based behavioral activation treatment helps adults with depression who have APS involvement and may reduce neglect or self-neglect behaviors.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06910267

• Launching! to Adulthood program for young adults with autism

  This program tests whether the Launching intervention helps young adults with autism improve daily living skills, readiness for adult roles, and social thinking compared with a delayed-treatment group.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06868537

• Telephone/video behavioral activation to prevent depression after a first stroke in low-income older adults

  This project will test whether coaching-style behavioral activation delivered by trained lay counselors over phone or video can prevent depression in low-income older adults who recently had a first stroke and currently have mild or no depressive symptoms.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06864715

• Virtual reality–enhanced CBT for social anxiety in autistic adults

  This program will see if adding virtual reality exposure and VR social-skills practice to CBT reduces social anxiety in adults with autism.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06845488

• Combining endoscopic ultrasound radiofrequency ablation with immunotherapy for advanced pancreatic cancer

  This study is testing a new treatment that combines a special type of ultrasound therapy with chemotherapy and immunotherapy to see if it helps people with advanced pancreatic cancer live better and longer.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06831136

• Microbiome transplant to treat constipation and bloating in systemic sclerosis

  This Phase 2 trial tests whether a frozen or lyophilized microbiome transplant (PRIM‑DJ2727) can help people with systemic sclerosis who have constipation and/or significant bloating.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06827977

• Vale+Tú Salud corner program to help Latino day laborers prevent COVID-19

  This program will test whether Vale+Tú Salud helps Latino day laborers increase social distancing, hand-washing, and PPE use.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06821113

• Comparing laser treatment and magic mouthwash for pain relief in kids with mouth ulcers

  This study is testing whether laser treatment works better than Magic Mouthwash to help kids with painful mouth ulcers feel better.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06819033

• Using a video tool to improve end-of-life care discussions for older trauma patients

  This study tests whether a video tool can help older trauma patients and their families have better conversations about end-of-life care preferences.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06804226

• Autologous fat-derived stem cell treatment for early Alzheimer's disease.

  This trial will test whether infusions of a person's own fat-derived stem cells can reduce brain inflammation and improve thinking in adults with early Alzheimer's disease or mild cognitive impairment.

  Recruiting Phase 1/2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06775964

• Fetoscopic balloon (FETO) for severe left and right congenital diaphragmatic hernia — long-term outcomes

  This trial will try placing and later removing a tiny balloon in the fetal windpipe around 27–29 weeks to help babies with severe congenital diaphragmatic hernia and liver herniation survive the newborn period.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06739356

• ViTrack continuous non-invasive wrist blood pressure monitoring for surgical patients

  This test sees if the ViTrack wrist device can continuously track blood pressure in adults having noncardiac surgery who need an arterial line.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06719518

• Preventing kidney injury after heart surgery with a proton pump inhibitor

  This study is testing if giving the heart surgery patients a medication called pantoprazole can help prevent kidney injuries after their surgery.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06706258

• Assessing the safety and acceptability of psilocybin for Bipolar II depression

  This study is testing if giving two doses of psilocybin along with therapy can be a safe and helpful treatment for people with Bipolar II Disorder who are feeling depressed and suicidal.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06706232

• Assessing the effectiveness of povidone-iodine irrigation for perforated appendicitis

  This study tests if using povidone-iodine irrigation during surgery can help people with perforated appendicitis recover better and save on treatment costs compared to standard care.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06705842

• Diphenhydramine for cervical edema during active labor

  This will test whether a single IV dose of diphenhydramine given during active labor can prevent labor arrest and lower cesarean delivery rates in first-time (primiparous) women.

  Recruiting Phase 2/3 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06702670

• Online Neurobehavioral Therapy for Veterans with Epilepsy and Depression

  This study is testing an online therapy program with text messaging support to see if it helps veterans with epilepsy and depression feel better.

  Recruiting at 2 sites The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT06695767

• Registry for pediatric bipolar disorder in the Greater Houston Area

  This study is looking at children and teens with bipolar disorder, their siblings, and healthy kids to see how their genes and brain structures relate to mood changes.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06665984

• 24-hour clear liquid diet before anesthesia for people taking GLP-1 receptor agonists

  This trial will test whether switching to a clear liquid diet for 24 hours before upper endoscopy reduces leftover stomach contents in people taking GLP-1 receptor agonist medications.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06654219

• Routine and rapid point-of-care syphilis testing for pregnant people in the ER and OB triage

  This project will offer quick point-of-care and standard lab syphilis tests in the emergency department and obstetric triage to see if that helps pregnant people without prenatal care get diagnosed and start treatment sooner.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06645106

• Improving HPV vaccination rates among Latino adolescents in health centers

  This study is testing new ways to help healthcare providers encourage Latino teens to get the HPV vaccine in health centers that serve their communities.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06598475

• Using light therapy to reduce pain and improve healing after dental surgery

  This study is testing whether light therapy can help reduce pain and speed up healing for people who have just had dental surgery.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06574152

• Impact of a school-based fruit and vegetable program on child and parent health in low-income areas

  This study is testing whether a program that gives fresh fruits and vegetables to kids and their families can improve their health and eating habits in low-income areas.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06570707

• Intervention to help women with trauma-related conditions use HIV prevention medication

  This study is testing a new program to help women dealing with trauma feel more comfortable using HIV prevention medication called PrEP while they receive mental health treatment.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06558825

• Comparing two irrigation systems for cleaning infected root canals in teeth with pulp necrosis

  This study is testing which of two cleaning methods, GentleWave or EdgePro, works better to disinfect infected root canals in teeth with dead pulp.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06554366

• Ear-based vagus nerve stimulation paired with arm rehabilitation for cervical spinal cord injury

  This project tests whether ear-based vagus nerve stimulation combined with upper-limb rehabilitation is safe and helps improve hand and arm function in adults with chronic incomplete cervical spinal cord injury.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT06543277

• Comparing early proton pump inhibitor use to standard care for kidney injury in trauma patients

  This study is testing if giving the heartburn medication pantoprazole early can help prevent kidney injury in trauma patients who are in shock.

  Recruiting Phase 2/3 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06531642

• Setting care priorities for older women after breast cancer treatment

  This project will test a patient‑priorities approach to see if it helps older women who finished breast cancer treatment get survivorship care that matches their goals.

  Recruiting at 3 sites Phase 2 The University of Texas Health Science Center, Houston · Bellaire, Texas and 2 other locations · NCT06478589

• Managing blood flow after spinal cord injuries

  This study is testing different ways to manage blood flow in people with recent spinal cord injuries to see which method helps them recover better and avoid other health problems.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06451133

• Effects of a sleep medication on cravings and stress in stimulant use disorder

  This study is testing whether a sleep medication can help people in early recovery from stimulant use feel less stressed and have fewer cravings while they are in a treatment program.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06444256

• Comparing Transdiagnostic Behavior Therapy to Standard Treatment for Adjustment Disorder in Veterans

  This study is testing whether a new type of therapy called Transdiagnostic Behavior Therapy can help veterans with Adjustment Disorder feel better compared to standard problem-solving therapy.

  Recruiting The University of Texas Health Science Center, Houston · Charleston, South Carolina · NCT06433271

• Using curved and straight fetoscopes for in-utero surgery

  This study is testing whether using a curved fetoscope for in-utero surgeries can lead to better outcomes for fetuses and newborns compared to using a straight fetoscope or no fetoscope at all.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06425471

• Comparing humidity levels in incubators for extremely premature infants

  This study tests whether keeping extremely premature infants in incubators with higher humidity levels can help prevent dehydration and improve their health without harming their chances of survival.

  Recruiting at 9 sites The University of Texas Health Science Center, Houston · Birmingham, Alabama and 8 other locations · NCT06399861

• Improving brain connectivity in schizophrenia using neuromodulation

  This study is testing whether a special type of brain stimulation can help improve thinking and emotional responses in people with schizophrenia by enhancing the brain's white matter.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06345963

• Using Nicotinamide Riboside to Treat Smooth Muscle Dysfunction Syndrome

  This study is testing if Nicotinamide Riboside can help people with Smooth Muscle Dysfunction Syndrome and a specific genetic mutation by looking at its effects on glucose levels and safety.

  Recruiting Phase 1 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06280482

• Fresh Connect Food Rx to improve nutrition for high‑risk pregnant mothers

  This project will test whether giving low-income, high-risk pregnant women in Houston a Fresh Connect Food Rx card to buy fresh produce plus nutrition education helps limit gestational weight gain and improve pregnancy, birth, and food security outcomes.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06275568

• Houston Hospital-Based Violence Intervention Program to prevent repeat firearm injuries

  This project will test whether a hospital-based violence intervention (Houston-HVIP) can reduce repeat firearm injuries and improve mental, behavioral, and physical health over 12 months in people ages 16–35 treated for gunshot wounds.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06263647

• A program to help seniors reduce depression and improve social engagement after leaving protective services

  This study tests an 8-week program to help older adults who have experienced abuse or neglect feel less depressed and connect more with others after leaving protective services.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06257095

• Effects of light therapy on recovery from concussion in teens

  This study is testing if light therapy can help teenage athletes recover better from sports-related concussions compared to regular treatment.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06239818

• Continuous postoperative vital sign monitoring: blinded vs unblinded wearable sensor

  This study tests whether keeping clinicians blinded to continuous heart rate, oxygen saturation, and breathing data vs making data visible affects patient safety after major non-cardiac surgery.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT06232876

• Personalized audio imagery with compact EEG to improve sleep for inpatients with psychosis

  This project tests whether individualized audio imagery delivered with compact EEG can improve sleep, psychosis symptoms, and suicidal thoughts in hospitalized patients with psychosis.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06194344

• Using semaglutide to help manage weight after quitting smoking

  This study is testing if a weight loss medication called semaglutide can help people who have recently quit smoking manage their weight better.

  Recruiting at 2 sites Phase 2 The University of Texas Health Science Center, Houston · Austin, Texas and 1 other locations · NCT06173778

• Behavioral intervention to improve PrEP adherence for women with substance use disorders

  This study is testing a new support program to help Black and Hispanic women with substance use issues take their PrEP medication more regularly and effectively.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06158607

• Home-delivered produce with optional AI meal helper for high-risk pregnant women

  This program tests whether giving Medicaid-eligible, high-risk pregnant women in Harris County home-delivered produce plus an AI chat helper helps them use the food and eat healthier.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06114199

• Multi-level prevention program for sexual assault and harassment in active duty airmen

  This study is testing a new program to see if it can help active duty airmen prevent sexual assault and harassment by promoting respectful relationships and positive bystander behavior.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06101056

• Improving syphilis testing for pregnant women and newborns

  This study is testing two new ways to improve syphilis testing for pregnant women and their newborns to make sure they get the right care.

  Recruiting at 9 sites The University of Texas Health Science Center, Houston · Los Angeles, California and 8 other locations · NCT06082453

• Improving HIV prevention and substance use in homeless youth

  This study is testing a new program called MY-RIDE to see if it can help homeless youth reduce substance use and improve their HIV prevention efforts.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06074354

• A test to differentiate between bacterial and viral infections in emergency patients

  This study is testing a new blood test to see if it can help doctors tell the difference between bacterial and viral infections in adults with respiratory illnesses in the emergency room.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06070688

• Modified lumbar puncture procedure to reduce headaches

  This study is testing a new way to do lumbar punctures to see if it can lower the chances of headaches afterwards for people who need this procedure.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06062446

• Using cryopreserved human umbilical cord to repair spina bifida in fetuses

  This study is testing whether using preserved human umbilical cords can help repair spinal cord defects in fetuses with spina bifida to improve their health and development.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06042140

• Using a digital tool to monitor symptoms in head and neck cancer patients

  This study tests if a new digital tool that helps head and neck cancer patients report their symptoms during radiation therapy can improve their swallowing, taste, smell, and social life compared to standard care.

  Recruiting at 2 sites The University of Texas Health Science Center, Houston · Kansas City, Kansas and 4 other locations · NCT06030011

• tACS for neuropathic pain after spinal cord injury

  Researchers are testing whether transcranial alternating current stimulation (tACS) can help manage neuropathic pain in people who have had a spinal cord injury.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06029075

• tACS for motor recovery after stroke

  This study tests whether transcranial alternating current stimulation (tACS) can help adults who are at least 6 months post-stroke regain finger movement.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06029062

• Comparing intubation conditions using rocuronium and succinylcholine

  This study tests whether using rocuronium or succinylcholine makes it easier and safer to put a breathing tube in patients during surgery.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT06029049

• Understanding brain function in epilepsy and brain tumor patients

  This study is trying to see how brain function differs between healthy people and those with epilepsy or brain tumors by using special imaging and brain mapping techniques.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05989893

• Assessing the SafeLM Supraglottic Airway for Anesthesia

  This study tests if the SafeLM supraglottic airway device can safely help manage breathing during elective surgeries with general anesthesia.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05989880

• Exploring how electrical stimulation affects constipation in systemic sclerosis patients

  This study is testing whether a new electrical stimulation treatment can help people with systemic sclerosis who have constipation feel better by improving how their digestive system works.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05989763

• Using brain stimulation to improve outcomes in cocaine use disorder

  This study is testing if a type of brain stimulation can help adults with cocaine addiction feel more motivated and improve their treatment outcomes.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05986578

• Breathing techniques to prevent seizure-related breathing failure

  This study is testing breathing techniques to see if they can help people with hard-to-treat epilepsy breathe better during seizures.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05981755

• Screening for elder mistreatment in home-based primary care

  This study is testing a new tool to help doctors who visit older patients at home spot and report cases of elder mistreatment more effectively.

  Recruiting at 7 sites The University of Texas Health Science Center, Houston · Birmingham, Alabama and 6 other locations · NCT05958654

• Investigating the brain mechanisms of PTSD

  This study is testing a new way to understand PTSD by looking at brain activity in people with PTSD and healthy volunteers while using a special type of brain stimulation.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05895006

• Comparing a new graft to standard care for rotator cuff repair

  This study tests if a new graft can help people heal better and regain shoulder function after rotator cuff repair surgery compared to standard treatment.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05894265

• Comparing warm humidified CO2 and dry CO2 for pain management in bariatric surgery

  This study is testing if using warm, humidified carbon dioxide during bariatric surgery can help reduce pain and the need for pain medication afterward.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05838300

• Registry and biorepository for patients with suspected Amniotic Fluid Embolism

  This study is setting up a registry to collect information from patients suspected of having Amniotic Fluid Embolism to better understand the condition.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05791786

• Evaluating fecal microbiota transplantation for ulcerative colitis treatment

  This study is testing if a new treatment using fecal microbiota transplantation can help people with active ulcerative colitis feel better.

  Recruiting Phase 1 The University of Texas Health Science Center, Houston · Houston, Texas · NCT05786404

• Combined evidence-based steps to make primary care diagnosis safer and faster

  This project will test whether combining three evidence-based steps for primary care teams makes diagnosing anemia and reduced kidney function safer and faster for patients at participating clinics.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05735314

• Registry of outcomes and practices for extremely premature infants

  This study is trying to gather information about the health and care of extremely premature infants born at 22-23 weeks to help improve their treatment and outcomes.

  Recruiting at 59 sites The University of Texas Health Science Center, Houston · Birmingham, Alabama and 58 other locations · NCT05685745

• Using ultrasound to improve patient selection for vaginal surgery

  This study is testing if using trans-vaginal ultrasound can help doctors choose the right women for a specific type of minimally invasive vaginal surgery.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05623514

• Using Deep Brain Stimulation to Preserve Memory in Epilepsy

  This study is testing whether a new brain stimulation technique can help people with Mesial Temporal Lobe Epilepsy have fewer seizures and better memory.

  Recruiting at 2 sites The University of Texas Health Science Center, Houston · Rochester, Minnesota and 1 other locations · NCT05608408

• Mapping brain responses to deep brain stimulation in epilepsy patients

  This study is testing how electrical stimulation in the brain affects people with severe epilepsy who already have devices implanted to see if it can lead to better treatments.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05600738

• Using targeted TMS to improve fear extinction in PTSD patients

  This study is testing how different ways of using a brain stimulation technique called TMS can help people with PTSD manage their fear better.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05368987

• Home-based brain stimulation for symptoms in Huntington's Disease

  This study is testing if a type of brain stimulation can help people with Huntington's Disease feel better by reducing symptoms like apathy, irritability, and depression.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05326451

• Virtual reality therapy for college students with anxiety

  This study tests whether virtual reality therapy can help college students feel less anxious and improve their confidence in school.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05319509

• Using brain stimulation to help people with schizophrenia quit smoking

  This study tests whether a type of brain stimulation can help people with schizophrenia quit smoking by comparing two different methods.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05276050

• Using brain imaging to personalize electric stimulation for treating anhedonia in bipolar depression

  This study is testing if a type of brain stimulation can help people with bipolar depression who struggle to feel pleasure and see if it makes a difference in their symptoms.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05240352

• Platelet-rich plasma to prevent uterine scar problems after cesarean

  This test will see if applying your own platelet-rich plasma to the uterine incision at an elective term cesarean can reduce scar-related bleeding, pain, and menstrual problems.

  Recruiting The University of Texas Health Science Center, Houston · Ramat Gan, Center · NCT05224726

• Stopping routine inhaled nitric oxide during newborn stabilization for congenital diaphragmatic hernia

  This study will test whether stopping inhaled nitric oxide during initial resuscitation helps newborns with CDH avoid extracorporeal life support (ECLS) or death.

  Recruiting at 19 sites Phase 4 The University of Texas Health Science Center, Houston · Birmingham, Alabama and 18 other locations · NCT05213676

• Understanding how genetics affect GLP-1 response in Mexican-Americans with prediabetes

  This study is trying to see how genetics affect how well GLP-1 therapy works for Mexican-Americans with prediabetes, to help create better, personalized treatments.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Brownsville, Texas · NCT05119179

• Comparing AI and traditional methods for analyzing pancreatic lesions

  This study is testing if using artificial intelligence to analyze pancreatic tissue samples can give accurate results compared to having a doctor look at them right away.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05018663

• Using ultrasound-guided radiofrequency ablation with chemotherapy for pancreatic cancer treatment

  This study is testing if combining a special ultrasound treatment with chemotherapy can help shrink pancreatic cancer tumors before surgery to make the surgery easier and more successful for patients.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT04990609

• Home-based exercise and meal delivery for frail older adults

  This study tests if a combination of home exercise and meal delivery can help frail older adults move better and improve their overall health.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04906759

• Managing blood pressure during major surgery

  This study tests whether a tighter blood pressure management method during major surgery can help patients keep their blood pressure stable compared to regular management.

  Recruiting at 15 sites The University of Texas Health Science Center, Houston · Omaha, Nebraska and 19 other locations · NCT04884802

• Responsive parenting intervention for toddlers born preterm

  This study is testing if a special program can help parents be more responsive to their toddlers who were born early, to see if it improves the children's development and brain growth.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04856501

• Community-based program for youth with opioid use disorder

  This study is testing a community program that helps young people with opioid use disorder get better treatment and support to see if it keeps them engaged in recovery and reduces overdoses.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT04811014

• Using Ketorolac to improve recovery after palatoplasty for cleft lip and palate

  This study tests if giving Ketorolac along with regular pain relief can help patients recover better and eat more easily after surgery for cleft lip and palate.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT04771156

• Understanding how PTSD patients learn to avoid fear triggers

  This study is testing how people with PTSD learn to avoid things that trigger their fear and how their brain reacts to this learning.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04770584

• BreEStim for motor recovery after chronic stroke with moderate impairment

  A small pilot test will try Breathing-controlled electrical stimulation to see if it reduces finger muscle tightness and improves hand function in people who had a stroke more than 6 months ago.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04752319

• BreEStim for motor recovery after chronic stroke with severe finger spasticity

  This pilot test checks whether Breathing-controlled electrical stimulation (BreEStim) can reduce finger flexor spasticity and improve hand function in people who have had a stroke at least 6 months ago with serious impairment.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04750564

• Breathing-controlled electrical stimulation to help hand function after stroke

  A new treatment using BreEStim tests whether combining breathing control with electrical stimulation can reduce finger flexor tightness and improve hand movement in people who are several months post-stroke.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04750551

• Effects of Acupuncture on Patients with Epilepsy Using RNS

  This study is testing whether acupuncture can help improve mood, thinking, and reduce seizures in people with epilepsy who have a Responsive Neurostimulation system.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04677751

• Oral fecal microbiota transplant for preventing ulcerative colitis relapse

  This study is testing whether taking special capsules made from gut bacteria can help adults with ulcerative colitis stay in remission and avoid flare-ups.

  Recruiting Phase 2 The University of Texas Health Science Center, Houston · Houston, Texas · NCT04373473

• Evaluating cost effectiveness of bone grafting methods for cleft lip and palate patients

  This study is testing whether new bone grafting methods using BMP and DBM can be more effective and less painful than traditional bone grafts for patients with cleft lip and palate.

  Recruiting Phase 4 The University of Texas Health Science Center, Houston · Houston, Texas · NCT04234971

• Using iGlucose Device to Improve Blood Sugar Management in Pregnant Women with Diabetes

  This study is testing if using the iGlucose device can help pregnant women with diabetes better manage their blood sugar levels compared to regular care.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04206748

• Comparing magnetic seizure therapy and electroconvulsive therapy for bipolar depression and treatment-resistant depression

  This study is testing whether magnetic seizure therapy works better than electroconvulsive therapy for people with bipolar depression who haven't found relief from other treatments.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT04080778

• Precision medicine for heritable thoracic aortic disease

  This study is trying to learn more about genetic factors in people with heritable thoracic aortic disease to help doctors better predict risks and manage their care.

  Recruiting at 20 sites The University of Texas Health Science Center, Houston · Newport Beach, California and 19 other locations · NCT04005976

• Exploring brain inflammation in neuropsychiatric conditions

  This study is testing if brain inflammation is linked to the severity of symptoms in people with mood disorders, chronic pain, dementia, and substance abuse.

  Recruiting Phase 1 The University of Texas Health Science Center, Houston · Houston, Texas · NCT03705715

• Using stem cells to treat bipolar depression that doesn't respond to other treatments

  This study is testing whether stem cells can help people with bipolar depression who haven't found relief from other treatments feel better.

  Recruiting Phase 1 The University of Texas Health Science Center, Houston · Houston, Texas · NCT03522545

• Research on genetic factors in Turner Syndrome and heart defects

  This study is testing the genetic differences between women with Turner Syndrome who have a specific heart defect and those who don’t, to better understand heart risks for these patients.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT03185702

• Database for patients with Leigh syndrome

  This study is creating a database to gather information from people with Leigh syndrome to better understand the condition and improve treatment options.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT03137355

• Improving quadriceps function after knee surgery with blood flow restriction training

  This study is testing if adding blood flow restriction training to physical therapy can help people recovering from knee surgery feel stronger and recover better.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT03096366

• Using targeted brain stimulation to treat auditory hallucinations in schizophrenia

  This study is testing a new brain stimulation treatment to see if it can help people with schizophrenia who hear voices feel better and improve their memory and attention.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT02916810

• Observational study on cluster headaches and trigeminal neuralgia

  This study is trying to learn more about cluster headaches and trigeminal neuralgia by gathering information from patients to help match them for future treatments.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT02910323

• Imaging techniques to improve diagnosis of epilepsy in children

  This study is testing new MRI techniques to see if they can help doctors better diagnose epilepsy in children who have severe, hard-to-treat cases.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT02846272

• Identifying biomarkers in blood and cyst fluid from patients with pancreatic cysts

  This study is trying to find helpful markers in blood and fluid from pancreatic cysts to improve how doctors diagnose and manage pancreatic conditions for patients with these cysts.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT02647177

• Comparing endovascular repair to best medical therapy for acute type B aortic dissection

  This study is testing whether adding a specific type of surgery to standard medical treatment can help people with a certain type of aortic dissection live longer and have a better quality of life.

  Recruiting at 2 sites The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT02622542

• Understanding brain changes in children with spastic diplegia after surgery

  This study is trying to see how surgery affects brain connections in children with spastic diplegia.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT02535936

• A repository for neuroscience research data and tissue samples

  This study is collecting health information and tissue samples from neurosurgery patients and their families to create a helpful database for future research on brain-related conditions.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT00857922

• Assessing blood coagulation in bleeding and clotting disorders

  This study is testing how well different blood tests can help understand blood clotting issues in people with bleeding or clotting disorders being treated at UTHealth Houston.

  Recruiting at 2 sites The University of Texas Health Science Center, Houston · Houston, Texas and 1 other locations · NCT00178594

Quick answers

How many clinical trials run by The University of Texas Health Science Center, Houston are recruiting right now?

145, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (144 trials), Australia (2 trials), Canada (2 trials), Japan (2 trials), Spain (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 12, Phase 4: 9, Phase 1: 5, Phase 2/3: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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