Evaluating cost effectiveness of bone grafting methods for cleft lip and palate patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial aims to compare the cost effectiveness of using Bone Morphogenic Protein (BMP) and Demineralized Bone Matrix (DBM) against traditional autologous Iliac Crest Bone Graft (ICBG) in patients undergoing alveolar bone grafting for cleft lip and palate. The study will assess whether the BMP/DBM approach leads to lower post-operative pain, shorter surgery times, and comparable bone healing rates. By analyzing these factors, the trial seeks to determine the most efficient and effective treatment option for this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with CLP(unilateral or bilateral)
* Radiographically evident open bone defect of the alveolus
* Dentition evaluated by orthodontist and cleared for ABG surgery

Exclusion Criteria:

* Patients without CLP
* Previous failed repair of alveolar cleft
* Patients who have previously undergone successful ABG
* Patients without an alveolar defect
* Patients whose parents refuse to consent to randomization
* Patients who have a syndromic CLP

Where it's running

• The University of Texas Health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Matthew Greives, MD — The University of Texas Health Science Center, Houston
• Study coordinator: Matthew Greives, MD
• Email: Matthew.R.Greives@uth.tmc.edu
• Phone: (713) 500-7275

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.