Personalized audio imagery with compact EEG to improve sleep for inpatients with psychosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Hospitalized patients with schizophrenia-spectrum disorders or mood disorders with psychotic features who report sleep problems receive either individualized imagery audio interventions paired with compact EEG monitoring or a control condition. The team uses brief EEG recordings and tailored audio scripts aimed at improving sleep continuity and reducing nightmares, delivered during the inpatient stay. Outcomes include changes in sleep quality, psychotic symptom measures, and suicidality, along with feasibility metrics for delivering the intervention on an inpatient unit. The protocol excludes patients with substance- or medically induced psychosis, major cognitive disorders, implanted devices, or high-frequency safety checks that would interfere with sleep monitoring.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* primary diagnoses of schizophrenia spectrum disorder or mood disorder with psychotic features, as determined by the treatment team or record review
* capacity to consent to the study as determined by licensed psychologists ( or the primary attending psychiatrist
* reported sleep dysfunction which will be determined by a subthreshold or more severe score ≥ 8 on the Insomnia Severity Index (ISI), and/or report experiencing nightmares at least once a week.

Exclusion Criteria:

* primary substance- or medical-induced psychosis
* intellectual and developmental disabilities
* neurodegenerative cognitive disorders
* implanted devices (e.g., Pacemakers)
* on one-to-one supervision or 15-minute safety checks for suicidality or aggression
* patients with roommates that are on 15-minute checks to minimize impact on study participants' awakenings

Where it's running

• The University of Texas Health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Alia Warner, Ph.D. — The University of Texas Health Science Center, Houston
• Study coordinator: Alia Warner, Ph.D., ABPP
• Email: Alia.R.Warner@uth.tmc.edu
• Phone: 713-486-2700

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.