Community-based program for youth with opioid use disorder

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Young Houston Emergency Opioid Engagement System (Young HEROES) is a community-based initiative aimed at improving treatment engagement for youths and adolescents with opioid use disorder. This non-randomized cohort study recruits participants through assertive outreach, community referrals, and emergency department referrals, providing immediate access to medication for opioid use disorder, behavioral counseling, and peer recovery support. The study evaluates the effectiveness of these combined interventions on patient outcomes, focusing on engagement and retention in treatment, as well as the prevalence of opioid overdoses among youth in Houston.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* In otherwise good health based on physician assessment and medical history
* Drug screen positive for opioids
* Patients express a willingness to stop opioid use
* Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence
* Patients must be able to speak English
* Be agreeable to and capable of signing the informed consent and assent (parent or guardian must consent, minor must assent)

Exclusion Criteria:

* Non-English-speaking patients
* Have a known sensitivity to buprenorphine or naloxone
* Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.
* Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)
* Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk
* Be a nursing or pregnant female

Where it's running

• The University of Texas Health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: James R Langabeer, PhD — The University of Texas Health Science Center, Houston
• Study coordinator: James R Langabeer, PhD
• Email: james.r.langabeer@uth.tmc.edu
• Phone: 713-500-3925

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.