vNOTE Hysterectomy with Uterosacral Suspension to Support Pelvic Organs

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates performing hysterectomy through a vaginal natural orifice (vNOTES) and adding a uterosacral suspension to preserve apical vaginal support. The approach aims to reduce abdominal incisions, potentially lowering pain and recovery time while maintaining or improving long-term pelvic health. Eligible participants are adult women undergoing vNOTES hysterectomy for benign gynecologic indications. The trial is conducted at a single site with UTHealth as the lead sponsor and does not list collaborating sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age\>18
* All women undergoing vNOTES hysterectomy ± Bilateral salpingectomy/salpingo-oopherectomy for benign gynecological indication

Exclusion Criteria:

* Exclusion for vNOTES surgery: pelvic inflammatory disease, previous rectal surgery, suspected malignancy, radiation
* Indication for surgery: elvic prolapse
* Other surgical interventions planned for the procedure

Where it's running

• University of Texas
  Houston, Texas, United States Recruiting

Study contacts

• Study coordinator: Aya Mohr Sasson, MD
• Email: aya.mohrsasson@uth.tmc.edu
• Phone: 346-270-4682

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predictors of Success and Failure of v-NOTES Hysterectomy for Large Uteri

  This study looks at which factors predict whether a v-NOTES hysterectomy for large uteri will be completed without needing to switch to another surgical approach.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07895953

• Hybrid robotic surgery for gynecologic procedures using ROB platform

  This study tests whether the ROB robotic platform and its endoscopic instruments can be safely used to perform laparoscopic hysterectomy with or without removal of tubes and/or ovaries in adult women.

  Recruiting Rob Surgical Systems S.L. · Inca, Balearic Islands and 1 other locations · NCT07832539

• Biofeedback-Assisted Pelvic Floor Training After Hysterectomy

  This study tests whether biofeedback-guided pelvic floor exercises after hysterectomy can improve pelvic floor strength, reduce urinary leakage, lessen genital prolapse, and boost quality of life.

  Recruiting Kafrelsheikh University · Kafr ash Shaykh, Kafrelsheikh · NCT07784465

• Effectiveness of M-TAPA nerve block for pain relief after laparoscopic hysterectomy

  This study tests whether the M-TAPA nerve block before surgery can reduce opioid use and pain after laparoscopic hysterectomy compared with standard pain care.

  Recruiting Istinye University · Istanbul · NCT07483190

• Reading a personal narrative book to help emotional regulation before hysterectomy in young women

  This trial tests whether reading a personal narrative book in addition to usual care can help young women preparing for hysterectomy feel calmer and less anxious or depressed.

  Recruiting at 4 sites Groupe SantéCité SantéCité Enseignement-Recherche-Innovation (GCS SCERI) · Bordeaux and 3 other locations · NCT07430488

• Preoperative counseling on keeping or removing ovaries for transmasculine people having hysterectomy

  This tests whether a short educational handout given before the first surgical visit helps transmasculine and non-binary people decide about keeping or removing their ovaries when having a hysterectomy.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07324967

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.