Assessing blood coagulation in bleeding and clotting disorders
Evaluation of Hemostasis in Bleeding and Thrombotic Disorders Using the Roteg Analyzer and the Thrombin Generation Assay
This study is testing how well different blood tests can help understand blood clotting issues in people with bleeding or clotting disorders being treated at UTHealth Houston.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 1 Day to 98 Years |
| Sex | All |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 2 sites (Houston, Texas and 1 other locations) |
| Trial ID | NCT00178594 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the coagulation system in individuals with bleeding and thrombotic disorders using advanced blood coagulation assays. Participants will undergo testing with the ROTEG analyzer and thrombin generation assay to assess their coagulation profiles. The study focuses on patients receiving treatment for congenital or acquired bleeding or clotting disorders at UTHealth Houston. The ROTEG analyzer provides continuous monitoring of blood coagulation from initial fibrin formation to clot dissolution, although it will not be used for diagnostic purposes.
Who should consider this trial
Good fit: Ideal candidates include individuals with congenital or acquired bleeding or clotting disorders who can provide informed consent.
Not a fit: Patients with poor venous access may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of coagulation disorders and inform future treatment strategies.
How similar studies have performed: Other studies using similar coagulation assessment techniques have shown promise, indicating potential for valuable insights in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: patients with congenital or acquired bleeding or clotting disorders who have provided informed consent and/or assent Exclusion Criteria: poor venous access
Where this trial is running
Houston, Texas and 1 other locations
- The Univerisity of Texas Health Science Center at Houston — Houston, Texas, United States (Recruiting)
- UT Physicians Women's Center-Texas Medical Center — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Miguel Escobar, M.D. — The University of Texas Health Science Center, Houston
- Study coordinator: Katherine Addy, RN, BSN, MPH
- Email: Katherine.E.Addy@uth.tmc.edu
- Phone: 713-500-8352
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.