Assessing blood coagulation in bleeding and clotting disorders
Official title: Evaluation of Hemostasis in Bleeding and Thrombotic Disorders Using the Roteg Analyzer and the Thrombin Generation Assay
Run by The University of Texas Health Science Center, Houston · NCT00178594 · Data updated 2026-11-12
This study is testing how well different blood tests can help understand blood clotting issues in people with bleeding or clotting disorders being treated at UTHealth Houston.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Day to 98 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 2 sites (Houston, Texas and 1 other locations) |
| Status | Recruiting |
| Started | October 2002 |
| Main results expected | January 2028 |
| Study ends | January 2028 |
| Registry record updated | January 9, 2025 |
| Trial ID | NCT00178594 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with congenital or acquired bleeding or clotting disorders who can provide informed consent.
✕Probably not a fit
Patients with poor venous access may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the coagulation system in individuals with bleeding and thrombotic disorders using advanced blood coagulation assays. Participants will undergo testing with the ROTEG analyzer and thrombin generation assay to assess their coagulation profiles. The study focuses on patients receiving treatment for congenital or acquired bleeding or clotting disorders at UTHealth Houston. The ROTEG analyzer provides continuous monitoring of blood coagulation from initial fibrin formation to clot dissolution, although it will not be used for diagnostic purposes.
Why it matters
Potential benefit: If successful, this study could enhance understanding of coagulation disorders and inform future treatment strategies.
How similar studies have gone: Other studies using similar coagulation assessment techniques have shown promise, indicating potential for valuable insights in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: patients with congenital or acquired bleeding or clotting disorders who have provided informed consent and/or assent Exclusion Criteria: poor venous access
Where it's running
-
The Univerisity of Texas Health Science Center at Houston
Houston, Texas, United States Recruiting -
UT Physicians Women's Center-Texas Medical Center
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Miguel Escobar, M.D. — The University of Texas Health Science Center, Houston
- Study coordinator: Katherine Addy, RN, BSN, MPH
- Email: Katherine.E.Addy@uth.tmc.edu
- Phone: 713-500-8352
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.