Temporary Clamping of Uterine and Ovarian Vessels During Minimally Invasive Myomectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates whether placing temporary clamps on the uterine and utero-ovarian arteries during minimally invasive myomectomy can lower intraoperative blood loss in patients with a high fibroid burden. The approach builds on existing evidence supporting reduced blood loss with vessel occlusion techniques and aims to specifically evaluate outcomes in high-burden cases. Eligible participants include adults undergoing MIS myomectomy for large intramural or submucosal fibroids or multiple fibroids, excluding those with pregnancy, under 18, concurrent gynecologic procedures, or suspected malignancy. The study will compare outcomes with and without the temporary vascular occlusion during the procedure. The lead sponsor is The University of Texas Health Science Center, Houston, at Memorial Hermann Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient undergoing minimally invasive myomectomy with either a single intramural or Submucosal fibroid =/\>5cm or
* Patients undergoing minimally invasive Myomectomy with =/\> 5 fibroids

Exclusion Criteria:

* Pregnancy,
* Age \<18yo,
* Patients undergoing concomitant surgery such as endometriosis surgery,
* Suspected malignancy

Where it's running

• Memorial Hermann Hospital
  Houston, Texas, United States Recruiting

Study contacts

• Study coordinator: Randa Jalloul, MD
• Email: randa.j.jalloul@uth.tmc.edu
• Phone: 3137128603

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Uterine artery ligation versus pericervical tourniquet to reduce bleeding during open myomectomy

  This trial will test whether tying the uterine arteries or using a pericervical tourniquet better reduces blood loss during open myomectomy for women with symptomatic uterine fibroids.

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• Ergometrine versus carbetocin to reduce bleeding during abdominal myomectomy

  This study will see if injecting ergometrine or carbetocin into the uterus during abdominal myomectomy reduces blood loss in women having surgery for symptomatic fibroids.

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• Preventing bleeding during myomectomy with misoprostol

  This will test whether giving misoprostol before myomectomy reduces surgical bleeding in women aged 18–43 having surgery for symptomatic uterine fibroids.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand, Clermont-Ferrand · NCT06882824

• Preventing adhesions after myomectomy surgery

  This study is testing whether a special gel used during myomectomy surgery can help prevent scar tissue from forming in women aged 18 to 45, which could improve their chances of getting pregnant later.

  Recruiting University Hospital, Ghent · Ghent · NCT05683041

• Comparing Terlipressin and Carbetocin for reducing blood loss during myomectomy

  This study is testing whether injections of Terlipressin or Carbetocin can help reduce blood loss during surgery to remove fibroids in women.

  Recruiting Wael Elbanna Clinic · Maadi · NCT05266534

• 15-year outcomes after sleeve gastrectomy in France

  This study looks at how people who had sleeve gastrectomy have fared over 15 years to see long-term weight changes and health effects.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07883018

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.