Measuring phosphorylated tau‑217 (pTau217) in donated blood plasma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, laboratory-based study will measure pTau217 concentrations in about 250 donated plasma samples collected through a blood bank, including purchased samples from clinically diagnosed Alzheimer's patients and healthy controls. Measurements will use a nanoneedle biosensor or equivalent immunoassays and will compare pTau217 concentrations to total tau. The design is cross-sectional and prospective, with aliquots retained for potential further analysis. The main goals are to determine how often donated plasma shows elevated pTau217 and to generate preliminary data relevant to transfusion safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The plasma sample from donators.

Exclusion Criteria:

* None.

Where it's running

• University of Texas Health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Zhongcong Xie, M.D., Ph.D. — The University of Texas Health Science Center, Houston
• Study coordinator: Zhongcong Xie, M.D., Ph.D.
• Email: Zhongcong.Xie@uth.tmc.edu
• Phone: 17135006207

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.