Online Neurobehavioral Therapy for Veterans with Epilepsy and Depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the feasibility and acceptability of an online group Neurobehavioral Therapy (NBT) combined with a text messaging intervention specifically designed for veterans suffering from epilepsy and major depressive disorder (MDD). Participants will engage in therapy sessions conducted over the internet, utilizing their home internet access and mobile devices for communication. The study focuses on veterans who are asymptomatic but have chronic conditions, ensuring they have the necessary technology and support to participate effectively.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* English speaking veterans
* has home internet access
* has access to and familiarity in using a computer or tablet at least weekly
* Asymptomatic patients with chronic conditions
* has access to a mobile device with Short Message Service (SMS) text and picture capability
* has an active clinical diagnosis of major depressive disorder based on the International Classification of Diseases, 10th version (ICD-10)
* has an ICD-10 diagnosis of epilepsy with at least one seizure documented within the last five years

Exclusion Criteria:

* pregnancy
* Veterans that have current suicidal ideation
* have active psychosis; and have an ICD-10 diagnosis of psychogenic non-epileptic seizures or conversion disorder.

Where it's running

• Michael E. DeBakey VA Medical Center
  Houston, Texas, United States Recruiting
• The University of Texas health Science Center at Houston
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Melissa Fadipe, MSN, APRN, FNP-C — The University of Texas Health Science Center, Houston
• Study coordinator: Melissa Fadipe, MSN, APRN, FNP-C
• Email: Melissa.F.Fadipe@uth.tmc.edu
• Phone: (713) 825-7237

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Mapping how repeated brain stimulation changes neural activity using implanted and scalp recordings

  This project will test whether repeated transcranial magnetic stimulation (TMS) changes brain activity in people with major depressive disorder or epilepsy by comparing direct recordings from implanted electrodes to noninvasive recordings.

  Recruiting Stanford University · Stanford, California · NCT05996900

• RAP-219 long-acting injectable safety and PK study in healthy adults

  This early study tests RAP-219-LAI in healthy adults to see how it behaves in the body and whether it is safe and tolerable.

  Recruiting Phase 1 Rapport Therapeutics Inc. · Adelaide · NCT07923097

• Dupilumab for Major Depressive Disorder

  This study tests whether dupilumab can engage immune targets in adults with major depressive disorder to see if it can help with depressive symptoms.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07908563

• Why People with Epilepsy Get More Infections

  This study tests whether anti-seizure medicines affect immune function and infection risk in people with epilepsy.

  Recruiting University of Aberdeen · Aberdeen · NCT07903168

• Long-Term Epilepsy Outcomes in Children After Perinatal Stroke

  This study looks at how epilepsy progresses in kids who had a stroke before 28 days old to see how their seizures and syndromes evolve over time.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07898397

• Hypothalamus structure and heart autonomic changes in drug-resistant epilepsy

  This study tests whether structural changes in the hypothalamus relate to cardiac autonomic dysfunction in adults with drug-resistant epilepsy.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT07888543

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.