Online Neurobehavioral Therapy for Veterans with Epilepsy and Depression

Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder

NA · The University of Texas Health Science Center, Houston · NCT06695767

This study is testing an online therapy program with text messaging support to see if it helps veterans with epilepsy and depression feel better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment16 (estimated)
Ages18 Years and up
SexAll
SponsorThe University of Texas Health Science Center, Houston (other)
Locations2 sites (Houston, Texas and 1 other locations)
Trial IDNCT06695767 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility and acceptability of an online group Neurobehavioral Therapy (NBT) combined with a text messaging intervention specifically designed for veterans suffering from epilepsy and major depressive disorder (MDD). Participants will engage in therapy sessions conducted over the internet, utilizing their home internet access and mobile devices for communication. The study focuses on veterans who are asymptomatic but have chronic conditions, ensuring they have the necessary technology and support to participate effectively.

Who should consider this trial

Good fit: Ideal candidates for this study are English-speaking veterans with internet access who have a clinical diagnosis of major depressive disorder and epilepsy.

Not a fit: Patients who are currently pregnant, experiencing suicidal ideation, or have active psychosis will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide veterans with a novel and accessible treatment option for managing both epilepsy and major depressive disorder.

How similar studies have performed: While this approach is innovative, similar studies exploring online therapies for mental health conditions have shown promising results, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English speaking veterans
* has home internet access
* has access to and familiarity in using a computer or tablet at least weekly
* Asymptomatic patients with chronic conditions
* has access to a mobile device with Short Message Service (SMS) text and picture capability
* has an active clinical diagnosis of major depressive disorder based on the International Classification of Diseases, 10th version (ICD-10)
* has an ICD-10 diagnosis of epilepsy with at least one seizure documented within the last five years

Exclusion Criteria:

* pregnancy
* Veterans that have current suicidal ideation
* have active psychosis; and have an ICD-10 diagnosis of psychogenic non-epileptic seizures or conversion disorder.

Where this trial is running

Houston, Texas and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Major Depressive Disorder, Epilepsy, veterans

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.