Comparing Transdiagnostic Behavior Therapy to Standard Treatment for Adjustment Disorder in Veterans
Comparative Effectiveness of Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure
NA · The University of Texas Health Science Center, Houston · NCT06433271
This study is testing whether a new type of therapy called Transdiagnostic Behavior Therapy can help veterans with Adjustment Disorder feel better compared to standard problem-solving therapy.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The University of Texas Health Science Center, Houston (other) |
| Locations | 1 site (Charleston, South Carolina) |
| Trial ID | NCT06433271 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of Transdiagnostic Behavior Therapy (TBT) compared to Treatment as Usual-Problem Solving Therapy (TAU-PST) for individuals diagnosed with Adjustment Disorder (AjD) following traumatic events. The research focuses on military personnel and veterans, who are particularly affected by AjD due to their experiences. Participants will be randomly assigned to receive either TBT or TAU-PST, and their symptom outcomes will be measured to determine which treatment is more effective. The study builds on preliminary findings that suggest TBT may offer significant benefits for managing AjD symptoms.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 who have served or are currently serving in the military and have a current DSM-5 diagnosis of Adjustment Disorder.
Not a fit: Patients with active psychosis, severe substance use, or suicidal ideation with clear intent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for veterans and military personnel suffering from Adjustment Disorder.
How similar studies have performed: While this approach is based on preliminary efficacy testing, it represents a novel application for treating Adjustment Disorder specifically in military populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult male or female over the age of 18 that has served, or is currently serving, in the military. * Stable psychotropic medication for at least 4 weeks if applicable * Current DSM-5 diagnosis of Adjustment Disorder Exclusion Criteria: * Active psychosis * Suicidal ideation with clear intent * Severe substance use
Where this trial is running
Charleston, South Carolina
- Ralph H. Johnson VA Health Care System — Charleston, South Carolina, United States (RECRUITING)
Study contacts
- Principal investigator: Ron Acierno, PhD — McGovern Medical School at UTHealth Houston
- Study coordinator: Stephanie M Hart, MPH
- Email: stephanie.hart4@va.gov
- Phone: 8435775011
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Adjustment Disorders, Mental Disorder, Veterans, Military Personnel