Comparing Transdiagnostic Behavior Therapy to Standard Treatment for Adjustment Disorder in Veterans
Official title: Comparative Effectiveness of Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure
Run by The University of Texas Health Science Center, Houston · NCT06433271 · Data updated 2026-11-12
This study is testing whether a new type of therapy called Transdiagnostic Behavior Therapy can help veterans with Adjustment Disorder feel better compared to standard problem-solving therapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 1 site (Charleston, South Carolina) |
| Status | Recruiting |
| Started | October 8, 2024 |
| Main results expected | July 2028 |
| Study ends | January 2029 |
| Registry record updated | December 6, 2024 |
| Trial ID | NCT06433271 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 who have served or are currently serving in the military and have a current DSM-5 diagnosis of Adjustment Disorder.
✕Probably not a fit
Patients with active psychosis, severe substance use, or suicidal ideation with clear intent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of Transdiagnostic Behavior Therapy (TBT) compared to Treatment as Usual-Problem Solving Therapy (TAU-PST) for individuals diagnosed with Adjustment Disorder (AjD) following traumatic events. The research focuses on military personnel and veterans, who are particularly affected by AjD due to their experiences. Participants will be randomly assigned to receive either TBT or TAU-PST, and their symptom outcomes will be measured to determine which treatment is more effective. The study builds on preliminary findings that suggest TBT may offer significant benefits for managing AjD symptoms.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for veterans and military personnel suffering from Adjustment Disorder.
How similar studies have gone: While this approach is based on preliminary efficacy testing, it represents a novel application for treating Adjustment Disorder specifically in military populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult male or female over the age of 18 that has served, or is currently serving, in the military. * Stable psychotropic medication for at least 4 weeks if applicable * Current DSM-5 diagnosis of Adjustment Disorder Exclusion Criteria: * Active psychosis * Suicidal ideation with clear intent * Severe substance use
Where it's running
-
Ralph H. Johnson VA Health Care System
Charleston, South Carolina, United States Recruiting
Study contacts
- Principal investigator: Ron Acierno, PhD — McGovern Medical School at UTHealth Houston
- Study coordinator: Stephanie M Hart, MPH
- Email: stephanie.hart4@va.gov
- Phone: 8435775011
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.