Comparing laser treatment and magic mouthwash for pain relief in kids with mouth ulcers

Effects of Photobiomodulation on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients

Phase 4 Interventional The University of Texas Health Science Center, Houston · NCT06819033

This study is testing whether laser treatment works better than Magic Mouthwash to help kids with painful mouth ulcers feel better.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment30 (estimated)
Ages5 Years to 17 Years
SexAll
SponsorThe University of Texas Health Science Center, Houston Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06819033 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of laser photobiomodulation (PBM) compared to 'Magic Mouthwash' in alleviating pain associated with aphthous ulcers in pediatric dental patients. It will assess how PBM influences the healing rate of these ulcers and measure changes in pain levels reported by the children undergoing treatment. The study will involve pediatric patients presenting with one or more aphthous ulcers during their dental appointments, with follow-up assessments conducted to monitor outcomes.

Who should consider this trial

Good fit: Ideal candidates are pediatric patients who present with one or more aphthous ulcers and have not previously received PBM treatment for these ulcers.

Not a fit: Patients with herpes labialis or systemic diseases affecting soft tissue healing may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective pain management option for children suffering from aphthous ulcers.

How similar studies have performed: While there is ongoing research in the field of photobiomodulation, this specific comparison of PBM and Magic Mouthwash in pediatric patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient/guardian speaks either English or Spanish
* Patient presenting with one or more aphthous ulcers in their mouth, identified during a scheduled dental appointment
* No previous PBM treatment to the presenting aphthous ulcer(s)
* Guardian able to partake in a follow-up phone call in either the English or Spanish language

Exclusion Criteria:

* Patient presents with aphthous ulcers recently treated with PBM
* Patient presents with herpes labialis (cold sores)
* Patients presents with systemic disease that affects soft tissue/mucous healing

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aphthous Ulcermagic mouthwashlaser treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.