Culturally Tailored Exercise Program for Hispanics with Multiple Sclerosis
Official title: Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis
Run by The University of Texas Health Science Center, Houston · NCT07606742 · Data updated 2026-11-12
A 16-week exercise program is being tested to see if it improves walking and quality of life for Hispanic adults with multiple sclerosis compared to a waitlist control.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 1 site (Houston, Texas) |
| Status | Recruiting |
| Started | August 24, 2026 |
| Main results expected | June 30, 2028 |
| Study ends | October 31, 2028 |
| Registry record updated | September 17, 2026 |
| Trial ID | NCT07606742 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with multiple sclerosis who self-identify as Hispanic/Latino, have walking disability, are relapse-free in the past 30 days, and can complete English or Spanish questionnaires.
✕Probably not a fit
Individuals with MS outside the targeted Hispanic/Latino population or with contraindications to exercise may not experience benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study enrolls adults with multiple sclerosis who identify as Hispanic/Latino and have walking disability. Participants are randomized to receive a 16-week culturally tailored exercise training program or a waitlist control. The primary outcome is change in walking dysfunction measured by MSWS-12, and secondary outcomes include health-related quality of life measured by MSWS-29. Eligibility requires confirmed MS, relapse-free status in the last 30 days, PDDS between 3.0 and 6.0, MSWS-12 between 25 and 75, and proficiency in English or Spanish. Exclusion criteria include significant exercise risks as determined by PAR-Q. The study is led by UT Health Houston with NIH collaboration, and is conducted at UT Health Houston in Houston, TX.
Why it matters
Potential benefit: If successful, participants may experience improved walking ability and quality of life through a culturally tailored exercise program.
How similar studies have gone: Prior research supports exercise to improve mobility in MS, but this specific culturally tailored approach in Hispanic populations is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * diagnosis of MS * relapse-free in the past 30 days * self-identify as Hispanic/Latino * Patient Determined Disease Steps Scale (PDDS) score between 3.0 (gait disability) and 6.0 (bilateral support) indicates walking disability. * MSWS-12 score between 25 and 75, indicating walking disability * Willingness to complete the questionnaires and undergo randomization * English or Spanish as a primary language Exclusion Criteria: * significant exercise-related risk factors or contraindications, assessed individually using the Physical Activity Readiness Questionnaire (PAR-Q; requires clearance from physician).
Where it's running
-
The University of Texas Health Science Center at Houston
Houston, Texas, United States Recruiting
Study contacts
- Principal investigator: Stephanie L Silveira, PhD — The University of Texas Health Science Center, Houston
- Study coordinator: Stephanie L Silveira, PhD
- Email: Stephanie.L.Silveira@uth.tmc.edu
- Phone: (713) 500-9490
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.