Comparing two irrigation systems for cleaning infected root canals in teeth with pulp necrosis
Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars: An In-vivo Study
This study is testing which of two cleaning methods, GentleWave or EdgePro, works better to disinfect infected root canals in teeth with dead pulp.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The University of Texas Health Science Center, Houston Academic / other |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT06554366 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of two irrigation systems, GentleWave and EdgePro, in disinfecting root canals of permanent teeth diagnosed with pulp necrosis. Participants will undergo nonsurgical root canal treatment, where the efficacy of these irrigation methods will be compared. The study will include patients who provide informed consent and meet specific inclusion criteria, while excluding those with certain dental conditions. The goal is to determine which irrigation system better reduces bacterial load in infected root canals.
Who should consider this trial
Good fit: Ideal candidates are individuals with permanent teeth diagnosed with pulp necrosis who are opting for nonsurgical root canal treatment.
Not a fit: Patients with root fractures, previously treated root canals, or vital pulps are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved outcomes in root canal treatments for patients with necrotic pulp.
How similar studies have performed: Other studies have shown promising results with similar irrigation techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Permanent teeth that are diagnosed with pulp necrosis. * elected to have a permanent tooth nonsurgical root canal treatment * Signed informed consent. Exclusion Criteria: * Teeth with root fractures or previously root canal treated teeth. * Teeth with severe loss of structure * Teeth with vital pulps.
Where this trial is running
Houston, Texas
- The University of Texas Health Science Center at Houston — Houston, Texas, United States (Recruiting)
Study contacts
- Principal investigator: David Jaramillo, DDS — The University of Texas Health Science Center, Houston
- Study coordinator: David Jaramillo, DDS
- Email: David.E.Jaramillo@uth.tmc.edu
- Phone: (713) 486-4224
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.