Fresh Connect Food Rx to improve nutrition for high‑risk pregnant mothers

Accelerating Healthcare Engagement in Healthy Food Interventions - Food Rx in High Risk Pregnant Mothers With About Fresh and Community Health Choice

Not applicable Interventional The University of Texas Health Science Center, Houston · NCT06275568

This project will test whether giving low-income, high-risk pregnant women in Houston a Fresh Connect Food Rx card to buy fresh produce plus nutrition education helps limit gestational weight gain and improve pregnancy, birth, and food security outcomes.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment620 (estimated)
Ages18 Years to 44 Years
SexFemale
SponsorThe University of Texas Health Science Center, Houston Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06275568 on ClinicalTrials.gov

What this trial studies

This interventional program provides consistent access to fresh produce through a Fresh Connect Food Rx card used at grocery stores combined with nutrition education and varying levels of engagement communication. Participants are enrolled at their first prenatal visit before 20 weeks' gestation and will be followed through 60 days postpartum (up to about 11 months). Comparison groups include usual care, Fresh Connect cardholder engagement, and enhanced engagement communication. Primary outcomes include gestational weight gain, other pregnancy and birth outcomes, and measures of food and nutrition security.

Who should consider this trial

Good fit: Ideal candidates are high-risk pregnant women receiving care through Texas Children's Health Plan in Houston who are under 20 weeks gestation and have overweight/obesity or a history of diabetes or hypertension.

Not a fit: Women who are not enrolled in Texas Children's Health Plan, present after 20 weeks gestation, or do not meet the listed high-risk criteria are unlikely to qualify or receive benefit from this program.

Why it matters

Potential benefit: If successful, this approach could reduce excessive gestational weight gain, improve some pregnancy and birth outcomes, and increase household food security for at-risk mothers.

How similar studies have performed: Previous produce-prescription and food‑is-medicine programs have improved fruit and vegetable intake and food security in other populations, but evidence specifically showing benefits for gestational weight gain and birth outcomes is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* high-risk pregnant mothers receiving care at Texas Children's Health Plan (TCHP) managed care organizations in Houston, Texas
* \<20 weeks medically confirmed viable pregnancy
* overweight/obese pre-pregnancy or at first trimester (self-report or measured BMI\>30.0), and/or prior history of diabetes or gestational diabetes, and/or prior history of hypertension or pregnancy-induced hypertension

Exclusion Criteria:

* not a high-risk pregnant mother receiving care at Texas Children's Health Plan (TCHP) managed care organizations in Houston, Texas

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nutrition in High-Risk Pregnancy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.