Sponsor or institution
Clinical trials and research at Fondazione Policlinico Universitario Agostino Gemelli IRCCS
As of November 12, 2026, Find a Trial lists 209 clinical trials run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS that are recruiting, at sites in 2 countries (most in Italy (209), Spain (1)). 1 was first registered in the last 30 days. By phase: Phase 1/2 (5), Phase 4 (2), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 209Clinical trials
- 1New in 30 days
- 2Countries
Newest trials
All recruiting trials (newest 150 of 209)
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How cinema sessions during chemotherapy might help cervical cancer patients
We’re testing if watching films during chemotherapy helps cervical cancer patients feel less anxious and improve quality of life.
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Ophthalmic Artery Doppler to predict labor problems before induction
This study tests whether measuring the ophthalmic artery Doppler in pregnant people at term who are being induced can help predict intrapartum fetal distress.
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GCP-R3 Practice Survey for Italian Clinical Researchers
Researchers in Italy are taking a web survey to see how well they understand and apply GCP E6(R3) and to identify barriers and training needs.
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Longitudinal profiling of plasma-derived glial extracellular vesicles in Alzheimer's disease
This study tests whether plasma glial extracellular vesicles and neuroinflammation biomarkers change over time across the Alzheimer’s disease spectrum and whether these signals relate to amyloid, tau, and neurodegeneration, with an additional step of exposing healthy iPSC-derived neurons to vesicles to see potential ne
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Amniotic Fluid DNA sequencing to detect infection in women with short cervix or PROM
This study tests a nanopore DNA sequencing method on amniotic fluid to see if it more reliably detects infection and inflammation than standard bacterial cultures in pregnant women with short cervix or premature rupture of membranes.
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Insomnia and Post-Dental Surgery Pain: A Look at Sleep Quality and Pain After Tooth Extractions
This study tests whether preoperative sleep problems influence how much pain people feel after routine tooth extractions.
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Evolution of Chronic Inflammatory Skin Diseases in Everyday Practice
This study follows people aged 12 and older with common inflammatory skin conditions to see how their disease changes over time using routinely collected clinical data.
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Impact of Weight on Work in Medical Residents
This study tests whether being overweight or obese affects how medical residents perform at work and feel about their quality of life over a year.
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Impact of TAVR on kidney function in people with aortic valve disease
This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.
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Bruxism Therapy with a Splint for Facial Pain
This study tests whether wearing a night-time occlusal splint changes jaw muscle activity in adults with temporomandibular disorders and chronic jaw pain, using a portable EMG device to track activity over 24 hours.
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Pancreatic Surgery and New Diabetes Risk in Adults without Diabetes
This study tests whether removing part or all of the pancreas during surgery affects blood sugar control and metabolism in adults who did not have diabetes before the operation.
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Interoception and Illness Perception Before and After Bariatric Surgery: See if interoceptive awareness changes with bariatric surgery
This study tests how awareness of internal bodily signals and beliefs about illness change from before to after bariatric surgery in adults with severe obesity.
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Understanding the tumor’s immune environment in pituitary tumors
This study tests how the tumor’s immune surroundings relate to pituitary tumors to help guide future treatments.
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Transitioning from pediatric to adult epilepsy care
This study looks at how moving from pediatric to adult epilepsy care works for young people aged 15 and up who have epilepsy, to see if a structured transition approach helps them navigate adult care better.
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Pediatric Epilepsies: How the illness progresses and affects thinking over time
This study will watch children and teens with epilepsy to see how cognitive function changes and what factors predict those changes.
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Vortioxetine for adults with depression who also have migraine
This project will try to see if taking vortioxetine helps adults with major depression who also have episodic migraine.
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National registry of endometrial cancer cases in Italy
This project will collect clinical and molecular information from adults treated for endometrial cancer at participating Italian oncology centers to see if a national database can improve understanding of outcomes and care.
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Early detection of high-grade serous ovarian cancer using DNA from Pap smear samples
This project will test whether DNA from Pap smears can detect early signs of high-grade serous ovarian cancer in women with inherited (germline) mutations who are having risk-reducing fallopian tube or ovary surgery.
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Real-world use of molecular classification for endometrial cancer
This project will try using molecular tests (POLE, p53, and mismatch-repair markers) in Italian hospitals to classify early-stage endometrial cancer and help guide adjuvant treatment decisions.
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ctDNA analysis on archived plasma to gauge minimal residual disease in epithelial ovarian cancer
A single-center study will test whether ctDNA from archived and current blood samples can help identify minimal residual disease in epithelial ovarian cancer patients after surgery.
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How drugs that affect the endocannabinoid system change bladder muscle contractions.
This work will test whether drugs that alter the endocannabinoid system change spontaneous and nerve‑driven contractions of bladder muscle using tissue from adults having radical cystectomy for bladder cancer.
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Early detection of progressive lung fibrosis in connective tissue diseases
This project will test whether blood extracellular vesicle biomarkers combined with AI-analyzed HRCT scans can detect and predict progressive interstitial lung disease in adults with connective tissue diseases.
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Survival in people with poor-prognosis epithelial ovarian cancer
We will collect clinical and tumor information to see if people with recurrent epithelial ovarian cancer who have a progression-free survival of 6 months or less have different survival outcomes.
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Preoperative Geriatric Assessment to Guide Hepatectomy in Older Adults
Aging patients planning liver surgery will be tested to see if a comprehensive geriatric assessment helps tailor perioperative care.
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ASO Therapy for Syndromic Craniosynostosis
This project tests patient-specific antisense oligonucleotides to see if they can address the molecular drivers of syndromic craniosynostosis in young children who are undergoing surgical skull remodelling.
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Gut microbiome in post-infectious irritable bowel syndrome
This project will test whether adults with post‑infectious IBS have different gut microbiome patterns compared with people who recovered from an infection and healthy adults.
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Predicting diabetes outcomes after a kidney transplant
This project will try to see if whole genome sequencing can help predict outcomes for adults who develop new diabetes after a kidney transplant.
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Bone mineral density in late pregnancy: singleton versus twin gestations
This project tests whether women with twin pregnancies have different bone mineral density in the third trimester than women carrying one baby, using two questionnaires and REMS ultrasound densitometry.
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Subclinical depression in people after a first heart attack (SUBDIMA25)
This project will test how common mild depressive symptoms are in adults hospitalized for a first heart attack and whether those symptoms relate to biomarkers, heart function, and recovery over the next year.
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RHYthm and Myocardial Function Relationship in Heart Disease
This study tests how heart rhythm patterns relate to heart muscle function in adults with arrhythmias or cardiomyopathy.
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Aortic Diseases and Quality of Life: How Work Ability is Affected
This observational study tests how living with aortic diseases affects quality of life, fatigue, mental well-being, and the ability to work in adults aged 18 to 70.
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Identifying new autoantibodies and causes of autoimmune encephalitis
This project looks for new autoantibodies and other disease features in adults with autoimmune encephalitis to help improve diagnosis and care.
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Spleen stiffness measurement to detect advanced liver fibrosis
This study will test whether measuring spleen stiffness with a 100‑Hz probe can help detect advanced fibrosis and portal hypertension in adults with MASLD and compensated advanced chronic liver disease.
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Bile acid and gut microbiota changes in people with hepatitis D starting bulevirtide
This project will see if starting bulevirtide changes bile acids and gut bacteria in adults with chronic hepatitis D who are already on hepatitis B therapy.
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Italian questionnaire to measure knowledge and vaccination attitudes in people without a spleen
This project will test a new Italian questionnaire to measure how much people without a spleen know about infection prevention and vaccination.
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Structured training for radiologic technologists to place peripheral venous access for contrast imaging
A structured training program is tested to see if radiologic technologists can safely and effectively place peripheral venous access for contrast imaging in adults.
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AI-guided automated fluid management for blood pressure control during laparoscopic colorectal surgery
This project will test whether an AI-guided automated fluid management system can help adults with ASA 3 undergoing laparoscopic colorectal surgery keep their blood pressure more stable and reduce episodes of low blood pressure during the operation.
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Education to prevent infections after spleen removal
See if a targeted educational program for adults who had their spleen removed improves vaccination uptake, awareness of infection risk, and continuity of care.
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Contrast-enhanced ultrasound to track how PRRT works in gastroenteropancreatic neuroendocrine tumors
This tests whether contrast-enhanced ultrasound can show treatment response to peptide receptor radionuclide therapy (PRRT) in adults with unresectable somatostatin-receptor–positive gastroenteropancreatic neuroendocrine tumors (GEP‑NETs).
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Aerobic exercise to improve thinking and brain health in Parkinson's disease
This project will try whether a year of regular aerobic exercise can help thinking and brain health in people with Parkinson's disease who have mild cognitive impairment.
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Technology-based cognitive-motor rehabilitation for frail older adults
This trial tests whether a combination of outpatient robotic therapy and asynchronous home telerehabilitation can help frail older adults with sensorimotor or cognitive problems do motor-and-thinking tasks better and reduce related risks.
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New Diagnostic Criteria to See How HCC Nodules Respond After Ablation
This study checks a new CEUS-based diagnostic approach to see if nodules after ablation respond as expected in people with hepatocellular carcinoma.
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Platform for women with BRCA1 or BRCA2 mutations in Italy
This project will try to collect clinical and follow-up data from women in Italy who carry pathogenic BRCA1 or BRCA2 mutations to build a national registry that can guide prevention and care.
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Avoiding a stoma after rectosigmoid surgery for advanced ovarian cancer
This trial tests whether avoiding a protective stoma after rectosigmoid resection is safe for people undergoing cytoreductive surgery for advanced ovarian cancer.
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Gingival Phenotype and Dental Crowding in Children
This study looks at how the thickness and other features of gums in kids relate to how their teeth crowd and how the gums might react to moving teeth with braces.
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Youth suicide risk factors and personalized reduction strategies in young adults
This study tests whether combining clinical data, genetic information, neuroimaging, and microbiome data can help identify risk factors and see if a dTMS-based intervention reduces suicide risk in young adults with mood disorders.
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Pasireotide LAR and bone health in adults with acromegaly
This study will test whether switching adults with uncontrolled acromegaly to pasireotide LAR changes bone turnover and the risk of vertebral fractures.
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Ultrasound elastography score to measure pancreatic fat
We will test an ultrasound-based score that measures pancreatic fat to see if it links to insulin-producing cell function and diabetes risk in adults with or at risk for metabolic syndrome.
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Health-Oriented Protocol for Epidermal Radiodermatitis
This study looks at how skin reactions from radiation therapy affect adults with head/neck or pelvic cancers and whether certain factors influence RID outcomes.
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2D-shear wave spleen elastography to detect clinically significant portal hypertension and high-risk esophageal varices
This study tests whether a 2D-shear wave spleen ultrasound can rule in or rule out clinically significant portal hypertension and high‑risk esophageal varices in adults with advanced chronic liver disease.
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Oxygen use and carbon dioxide production after stabilizing blood flow in shock
This project will see if giving fluids or norepinephrine to adults in the ICU with shock changes how much oxygen their bodies use and how much carbon dioxide they make, measured from the ventilator and compared with blood gas calculations.
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Maternal heart monitoring in pregnancies with fetal heart defects.
This project uses a noninvasive heart monitor on pregnant women carrying a fetus with a congenital heart defect to see if the mother's blood flow and heart measurements are linked to the baby's heart problem and pregnancy outcomes.
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Fertility-preserving hysteroscopic treatment outcomes for endometrial cancer and atypical hyperplasia
This project tests whether removing lesions by hysteroscopy combined with hormonal therapy helps women with endometrial cancer or atypical hyperplasia preserve fertility and achieve good pregnancy and cancer-control outcomes.
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AI-guided blood-pressure and fluid management during cytoreductive surgery with HIPEC
This trial will test whether an AI-based hemodynamic monitoring protocol during cytoreductive surgery with HIPEC helps adults with ovarian cancer avoid low blood pressure and fluid overload.
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Short-term fasting versus usual diet during chemotherapy for advanced ovarian cancer
This study will test whether short-term fasting around neoadjuvant chemotherapy lowers insulin and influences treatment response in women with advanced ovarian cancer.
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Gynecological Ultrasound Image Bank for Diagnostics and AI
This project will collect gynecological ultrasound images from adult patients at a Rome hospital to build a large database for clinician training, research, and AI diagnostic tools.
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Protein and tissue changes in the ligamentum flavum in lumbar spinal stenosis
This project will test whether specific protein and tissue changes in the thickened ligament behind the lower spine can be identified in people aged 50–85 having surgery for lumbar spinal stenosis.
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Real-time transperineal ultrasound-guided pushing training during pregnancy
This project will test whether adding a brief real-time ultrasound session to midwife-led pushing lessons helps pregnant, first-time mothers prepare for an easier and safer delivery.
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Job Rotation to Build Nursing Competencies and Improve Organizational Health
This study tests whether rotating nurses through different units improves their professional and clinical skills, reduces burnout, and enhances how the department functions.
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Using a prediction algorithm to prevent low blood pressure during abdominal aortic aneurysm repair
This trial will try whether using the Hemosphere platform's hypotension prediction index to guide hemodynamic therapy can reduce low blood pressure during abdominal aortic aneurysm repair.
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Long-term experience with pituitary tumors
This study looks at the experiences of over 1600 patients who had surgery for pituitary tumors to see what factors might affect their recovery and overall health.
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Jejunal pouch reconstruction after total gastrectomy
This study tests whether using a jejunal pouch during total gastrectomy helps reduce dumping syndrome and improve nutrition and quality of life in adults with gastric cancer or CDH1 hereditary risk.
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Identifying new treatment targets for childhood brain tumors
This study is trying to find new ways to treat a rare brain tumor in kids by looking at genetic markers that could make them respond better to a type of cancer drug used for breast cancer.
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Ultrasound changes in fibroids during relugolix‑estradiol‑norethisterone treatment.
This project will see if relugolix‑estradiol‑norethisterone changes the ultrasound appearance of fibroids in premenopausal women with heavy menstrual bleeding.
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OHANA — Optimizing cross-cultural care in hospitals
This project will see how matching patients and caregivers by cultural or language background affects the experiences of foreign patients and the nurses who care for them.
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Exploring the Role of AIRE in Autoimmune Neurological Diseases
This study is trying to see how the AIRE gene affects people with autoimmune neurological diseases like NMOSD, myasthenia gravis, and autoimmune encephalitis to improve diagnosis and treatment options.
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Comparing OSNA and ultrastaging to find sentinel lymph node metastases in endometrial cancer
This study tests whether the OSNA molecular test finds sentinel lymph node metastases as well as standard ultrastaging in people having surgery for early-stage endometrial cancer.
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Using parameter variation to guide blood pressure and circulation during major abdominal surgery
This study will test whether using percentage changes in monitoring parameters during major abdominal surgery can help keep blood pressure and circulation stable in adults.
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Injecting activated fat to treat chronic gastrointestinal and pelvic fistulas
This study is testing whether injecting activated fat can help people with long-lasting gastrointestinal and pelvic fistulas heal better and improve their quality of life.
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Using organoid models to study liver cancer
This study is trying to create mini-livers from patients' liver tissue to see how liver cancer behaves and how well different treatments work for people with the disease.
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Genomic profiling for patients with rare and genetic diseases
This study is trying to see if using advanced genetic testing can help doctors better understand and treat rare diseases for over 2 million patients in Italy.
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Monitoring blood flow during carotid surgery
This study is testing a new way to manage blood flow during carotid surgery to see if it helps patients have better outcomes compared to standard treatment.
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Evaluating outcomes in gastric cancer patients before and after a Tumor Board implementation
This study is trying to see if having a team of experts work together improves the surgery and treatment results for people with gastric cancer.
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Early lung development in preterm babies with and without fetal growth restriction
This study will test whether ultrasound measurements of fetal lung volume, diaphragm thickness and heart function before 32 weeks can help predict breathing problems and later lung function in preterm babies with or without fetal growth restriction.
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High-frequency ultrasound during gynecologic cancer surgery to check lymph nodes and build radiomics data
We will test whether using high-frequency ultrasound during surgery can help doctors check lymph nodes in women having operations for ovarian, endometrial, cervical, or vulvar cancer.
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Treating the main kidney tumor in metastatic kidney cancer during immunotherapy
This trial will see if adding surgery or radiotherapy to the main kidney tumor helps people with metastatic clear‑cell kidney cancer who are already benefiting from anti‑PD1–based therapy live longer.
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Link between muscle loss and nerve damage in adults with type 1 diabetes
This study is testing how muscle loss and nerve damage are related in adults aged 50-80 with type 1 diabetes.
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Understanding neoadjuvant treatment in early-stage breast cancer
This study looks at how many patients with early-stage HER2-positive and Triple Negative breast cancer received treatment before surgery over the last five years, and what types of treatments and surgeries they had.
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Registry and biobank for lymphatic malformations in Italy
This study is creating a registry and biobank to collect information and samples from people with lymphatic malformations in Italy to improve understanding and treatment of these rare conditions.
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Investigating biomarkers in unstable carotid plaque
This study is trying to see if certain markers in the blood can help understand the risks of heart problems in people with narrowed carotid arteries and different types of plaque.
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Exploring the immune profile of chronic hand eczema
This study is trying to understand the immune system's response in adults with chronic hand eczema to help create better, personalized treatments.
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Evaluating outcomes of thoracic aortic repair in patients with compromised landing zones
This study is testing different stent-graft options for patients with aortic aneurysms who have tricky anatomy to see if they can prevent complications after surgery.
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Managing asymptomatic carotid stenosis to prevent strokes
This study looks at whether surgery to clear blocked neck arteries can help older patients with no symptoms avoid strokes.
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Evaluating the effectiveness of target therapies for atopic dermatitis
This study is testing how well certain new treatments for moderate-to-severe atopic dermatitis work over a year for adults who are starting or already using them.
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Analyzing miRNAs in COVID-19 patients
This study is trying to see if certain tiny molecules in the blood can help predict how severe COVID-19 will be and if it might lead to death in adults who have tested positive for the virus.
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Digital prevention for liver disease management
This study is testing a new way to help people with liver disease by using a mobile app for patients and a dashboard for doctors to see if it improves their care and health outcomes.
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Using MRI to assess fertility-sparing treatment for cervical cancer
This study is testing how MRI can help women with early-stage cervical cancer who want to keep their ability to have children, by checking how well their fertility-sparing treatments are working.
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Evaluation of patients with traumatic and hypoxic-ischemic brain injuries
This study is trying to understand how brain injuries from trauma or lack of oxygen affect kids and young adults under 20, to find better ways to help them.
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Minimally invasive surgery for recurrent cervical or vaginal cancer
This study is testing a less invasive surgery for patients with recurring cervical or vaginal cancer to see if it can safely remove the cancer and improve their chances of staying cancer-free for three years.
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Assessing genetic variations in patients with neuromyelitis optica and multiple sclerosis
This study is trying to see if certain genetic differences in the FCGR3A gene are more common in Italian adults with neuromyelitis optica, MOGAD, or multiple sclerosis.
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Genetic analysis of patients with cervical artery dissections
This study is testing if certain genetic factors are linked to cervical artery dissections in adults and how these factors might affect their risk of having another dissection.
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Understanding patient outcomes in a Gut Microbiota Clinic
This study looks at how personalized gut treatments can help people with intestinal diseases by testing their gut microbiome and seeing how well these treatments work.
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Perceived quality of life after endoscopic vertical gastroplasty
This project tries to learn how adults in Italy feel about their quality of life at least six months after having endoscopic vertical gastroplasty.
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Examining gene alterations and chemotherapy response in advanced bladder cancer
This study is testing if certain gene changes can help predict how well advanced bladder cancer patients will respond to platinum-based chemotherapy treatments.
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Adjuvant Treatment in Premenopausal Breast Cancer (Oncotype DX-Based)
This study looks at how premenopausal women with early breast cancer who had the Oncotype DX test were treated after surgery and what their outcomes were.
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Public reactions to facial psoriasis, atopic dermatitis, vitiligo, and alopecia areata
This project tests how adults in the general population emotionally and socially respond to faces showing psoriasis, atopic dermatitis, vitiligo, or alopecia areata.
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Mitral valve annulus sizing with cardiac CT and 3D transesophageal echocardiography
This project will test whether preoperative cardiac CT and intraoperative 3D transesophageal echocardiography can provide mitral annulus measurements that match the surgeon's ring sizing for adults with severe mitral regurgitation undergoing repair.
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Analyzing immune cells in psoriasis skin during IL-23 therapy
This study is looking at skin samples from psoriasis patients who are not responding well to IL-23 therapy to see what immune cells might be causing their symptoms to come back.
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Using Zamidine eye drops to prevent infections during eye surgery
This study is testing if Zamidine eye drops can help prevent infections in patients having eye surgery by reducing harmful bacteria on the eye's surface.
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Identifying biomarkers in cervical mucus
This project will test whether infrared spectroscopy of cervical mucus can find biomarkers that distinguish women with unexplained infertility from healthy, fertile women.
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Exploring genetic and immune factors in heart failure
This study looks at how inflammation and genetic factors affect heart failure in older adults, especially focusing on differences between men and women.
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Evaluating balance in patients with strabismus undergoing surgery
This study is testing how surgery for strabismus affects balance and the risk of falling in patients with this eye condition.
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Evaluation of perioral tissue using advanced videodermoscopy
This study is testing the skin around the mouth in young adults to see what healthy tissue looks like, which could help with understanding mouth-related skin issues in the future.
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Evaluating long-term outcomes in adults with congenital heart disease
This study looks at adults with congenital heart disease to see what factors might lead to serious health issues over time, while they continue their regular check-ups.
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Impact of Childhood Trauma on Quality of Life in Multiple Sclerosis Patients
This study looks at how childhood trauma affects the quality of life and coping strategies of people with Multiple Sclerosis to see if those early experiences impact their health and treatment.
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Using CAR T-cell therapy to treat severe autoimmune diseases
This study is testing if a new CAR T-cell therapy can help people with severe autoimmune diseases like lupus and scleroderma feel better.
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Using AI to detect fetal brain anomalies during second trimester ultrasounds
This study is testing a new AI software to see if it can help doctors find brain problems in babies during second trimester ultrasounds.
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Evaluating heart health in adult cancer patients treated with cardiotoxic therapies
This study is trying to see how heart health is affected in adult cancer patients who have received treatments that might harm their hearts.
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Evaluating PSA response in metastatic prostate cancer
This study is testing how changes in PSA levels can help doctors understand how well treatments are working for men with advanced prostate cancer.
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Improving blood management for patients undergoing heart surgery
This study is testing if giving patients iron before heart surgery can help them recover better and need fewer blood transfusions.
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Evaluating MRI for ovarian masses in pregnant women
This study is testing whether MRI can help doctors better understand ovarian masses in pregnant women to improve their care.
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Using robotic ultrasound to evaluate lymph nodes in gynecological cancers
This study is testing a new robotic ultrasound method to see if it can help women with gynecological cancers check their lymph nodes during surgery, aiming to reduce the need for more invasive procedures.
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Using AI to improve safety in minimally invasive surgery for uterine cancers
This study is testing if using AI to analyze surgical videos can make minimally invasive surgeries for uterine cancers safer and help doctors spot problems during the operation.
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Endoscopic sleeve gastroplasty for obesity in patients with inflammatory bowel disease
This study is testing if a procedure called endoscopic sleeve gastroplasty can help people with obesity and inflammatory bowel disease improve their health and quality of life.
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Observational study on therapies for Inflammatory Bowel Disease
This study is testing new treatments for people with Inflammatory Bowel Disease who haven't had success with previous therapies to see how well they work.
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New procedure to keep mothers and newborns together
This study is testing a new way to care for newborns with breathing issues right after birth to see if it helps keep mothers and babies together and supports breastfeeding.
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Evaluating psychological well-being in breast cancer patients
This study looks at the mental health of women with early-stage breast cancer to see how they cope and feel before, during, and after surgery.
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Testing gut microbiome for colorectal cancer screening
This study is trying to see if testing the gut bacteria of people aged 50-74 who have a positive stool test can help find colorectal cancer earlier and reduce the need for unnecessary colonoscopies.
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New biomarkers to predict which pancreatic IPMNs will progress
This project will test whether tissue and blood biomarkers can help predict which adults with IPMN will progress to invasive pancreatic cancer.
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Pain management technique for robotic thymectomy
This study is testing a new pain management technique to see if it can help people having robotic thymectomy surgery feel less pain and recover better.
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Patient experience with early versus delayed attachment placement during clear aligner treatment
This trial tests whether delaying attachment placement until the third aligner reduces pain and improves quality of life for adults (18–40) receiving Biomax Nuvola clear aligners for malocclusion.
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Treatment for dry age-related macular degeneration using umbilical cord blood plasma
This study is testing if injections of umbilical cord blood plasma can help older adults with dry age-related macular degeneration slow down or improve their vision.
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Assessing lung health using ultrasound in emphysema patients
This study is testing if lung ultrasound can help doctors better understand lung health in people with emphysema compared to healthy individuals and those with lung cancer.
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How exposure to heavy metals, nanoparticles, and emerging contaminants relates to allergic skin and systemic metal reactions
This project will test whether adults with allergic contact dermatitis or systemic metal allergies have different levels of heavy metals, nanoparticles, and related blood and urine markers compared with healthy adults.
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3D analysis of palatal shape changes in children treated with a rapid palatal expander
This study looks at how a rapid palatal expander changes the shape of the mouth in children with different facial growth patterns to see how effective the treatment is.
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Testing different facemasks for noninvasive ventilation in respiratory failure
This study tests which of three different facemasks works best for helping people with severe breathing problems get rid of carbon dioxide.
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Measuring tissue oxygen levels during surgery for ovarian cancer
This study is testing if low oxygen levels in muscle during surgery for ovarian cancer can lead to kidney problems afterward in women undergoing treatment.
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Identifying markers for effective treatment of Myasthenia Gravis with complement inhibitors
This study is trying to find out which markers can help doctors know if complement inhibitor therapy will work well for people with generalized Myasthenia Gravis who have anti-AChR antibodies.
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Minimally invasive simple hysterectomy for low-risk cervical cancer
This study is testing if a less invasive surgery called a simple hysterectomy is safe for women with low-risk early-stage cervical cancer.
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Ultraaccelerated high-dose-rate intrauterine brachytherapy for locally advanced cervical cancer
This project tests a faster, higher-dose internal radiation (brachytherapy) after chemoradiation to see if bowel, bladder, vaginal, and sexual side effects are acceptable for people with locally advanced cervical cancer.
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Mental health and resilience in people with glioblastoma or head and neck cancer
We will see how common different psychological and psychiatric problems are, and whether resilience helps protect against them, in adults with glioblastoma or head-and-neck cancer who are receiving curative long-course radiotherapy.
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Next-generation treatments for Alzheimer's disease
This study is testing new treatments for Alzheimer's disease that aim to improve memory and learning by enhancing brain connections at a cellular level.
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Exploring stigma and psychological profiles in rectal and anal cancer patients
This study looks at the feelings and challenges faced by patients with rectal and anal cancer during long-term treatment to see how these issues affect their mental health and well-being.
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Assessing quality of life in anal cancer patients treated with radiotherapy
This study is trying to see how treatment affects the quality of life for anal cancer patients by having them fill out questionnaires about their symptoms and daily life over five years.
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Evaluating Micropulse Laser Treatment for Central Serous Chorioretinopathy
This study is testing if a special laser treatment can help people with central serous chorioretinopathy who haven't improved with other medications.
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Evaluating CT features in ovarian cancer for AI model development
This study is testing if certain CT scan features in women with advanced ovarian cancer can help create an AI model to predict surgery success and chemotherapy response.
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Understanding the spatial characteristics of ovarian cancer
This study is trying to see how different patterns in ovarian cancer tissue can help doctors create more personalized treatments for patients with High Grade Serous Ovarian Carcinoma.
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Characterizing breast cancer subtypes using patient-derived organoids
This study is testing if lab-grown mini-tumors from breast cancer patients can help doctors figure out which chemotherapy works best for people with triple-negative breast cancer or those whose cancer has come back.
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Evaluating radiochemotherapy and interventional radiotherapy for vaginal cancer
This study is testing a new treatment plan that combines radiation and chemotherapy for people with vaginal cancer to see if it helps them live longer and control the disease better.
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Comparing autonomic function in patients with cognitive decline
This study is testing how well a device can measure the automatic functions of the body in people aged 50 to 85 who have mild cognitive decline, like mild dementia or Alzheimer's, to better understand their condition.
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Measuring portal pressure in patients with advanced liver disease using endoscopic ultrasound
This study is testing if a new way of measuring pressure in the liver using endoscopic ultrasound is better than the traditional method for people with advanced liver disease and high blood pressure in the portal vein.
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Assessing a structured report for cervical cancer staging
This study is testing a new way to organize information about cervical cancer staging to see if it helps doctors be more consistent and improve care for patients.
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Investigating gut microbiota in patients with limb lymphedema and recurrent infections
This study looks at how the bacteria in the gut might be linked to limb lymphedema and repeated infections in patients to see if there are any important differences between those who have infections and those who don’t.
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Using blood tests to manage gastrointestinal tumors
This study is testing if blood tests that look for tumor DNA can help doctors better manage patients with gastrointestinal tumors like pancreatic, colon, and biliary tract cancers.
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Vaccinations to protect frail patients from pneumococcus, shingles, flu, hepatitis B, and COVID-19
This project uses hospital records to find frail adults who may be missing recommended vaccines and contacts them to offer pneumococcal, zoster, influenza, hepatitis B, and COVID-19 vaccination.
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Comparing surgery and medical treatment for breast cancer that has spread to the liver
This study is testing whether surgery or just medical treatment works better for people with breast cancer that has spread to the liver.
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Using patient-derived organoids to predict treatment response in ovarian cancer
This study is testing whether lab-grown mini-tumors from ovarian cancer patients can help predict how well they will respond to different cancer treatments.
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Assessing respiratory function in FSHD patients using diaphragmatic ultrasound
This study is testing how well diaphragmatic ultrasound can track changes in breathing function over a year in people with Facioscapulohumeral Muscular Dystrophy (FSHD).
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Study of characteristics in advanced lung cancer patients in Italy
This study looks at the different traits and features of patients with advanced lung cancer in Italy to better understand their condition at the time of diagnosis.
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Fecal microbiota transplantation for recurrent C. difficile infection in ulcerative colitis patients
This study is testing whether a single infusion of fecal microbiota transplantation can help people with ulcerative colitis who keep getting C. difficile infections feel better compared to a step-by-step approach.
Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.
Quick answers
How many clinical trials run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS are recruiting right now?
209, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in Italy (209 trials), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 5, Phase 4: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.