Identifying new treatment targets for childhood brain tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on medulloblastoma, a rare pediatric brain tumor, and aims to identify genetic markers that influence sensitivity to CDK4/6 inhibitors, which are currently used in breast cancer treatment. By utilizing high-throughput molecular biology techniques, the study will analyze the genetic and transcriptomic profiles of medulloblastoma to understand how these factors contribute to treatment resistance. The goal is to improve therapeutic strategies for children with this aggressive cancer by overcoming the limitations of existing treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients affected by Medulloblastoma operated on at the Pediatric Neurosurgery Unit during their pediatric age will be elected to take part to the study

Where it's running

• Fondazione Policlinico Gemelli Irccs
  Roma, Roma, Italy Recruiting

Study contacts

• Study coordinator: Gianpiero Tamburrini, Md
• Email: gianpiero.tamburrini@unicatt.it
• Phone: 3349468776

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.