Avoiding a stoma after rectosigmoid surgery for advanced ovarian cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Rectosigmoid resection with colorectal anastomosis is often required during cytoreductive surgery for advanced ovarian cancer and carries a reported anastomotic leakage risk of 1.7% to 17%. This interventional, single-center protocol at Fondazione Policlinico Universitario Agostino Gemelli IRCCS enrolls adults undergoing elective primary or secondary cytoreduction who require rectosigmoid resection and colorectal anastomosis and implements a no-stoma (no diverting ostomy) surgical policy. Participants provide informed consent and are followed for postoperative outcomes including anastomotic leakage, need for reoperation, and other surgical morbidity. Patients with non-ovarian histology, planned palliative surgery, or those who intraoperatively require an end ostomy are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with suspected or anatomopathological diagnosis of malignant ovarian tumor undergoing elective primary or secondary cytoreduction and needing rectosigmoid resection and anastomosis
* Informed consent signed prior to performing any procedure related to the clinical trial
* Age 18 years old.

Exclusion Criteria:

* Patients with histologies other than ovarian tumor.
* Only palliative surgery planned
* Patients who do not require sigmoid-rectum resection after intraoperative evaluation
* Patients who do not receive colorectal anastomosis and undergo end ostomy

Where it's running

• Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Ginecologia Oncologica
  Roma, Italy Recruiting

Study contacts

• Principal investigator: Virginia Vargiu — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
• Study coordinator: Virginia Vargiu
• Email: virginia.vargiu@policlinicogemelli.it
• Phone: +393387106039

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.