Investigating biomarkers in unstable carotid plaque

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationships between circulating microRNAs and both symptomatic and asymptomatic internal carotid artery stenosis (ICAS), as well as the morphology of carotid plaques and the occurrence of future cardiovascular events. Participants will undergo carotid endarterectomy, allowing researchers to collect data on their plaque characteristics and associated biomarkers. The study focuses on understanding how these biomarkers may correlate with the severity of carotid artery diseases and potential cardiovascular risks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy.
* Age\>18 years

Exclusion Criteria:

* Presence of significant internal carotid artery stenosis referred to carotid artery stenting

Where it's running

• Fondazione Policlinico Universitario A. Gemelli IRCCS
  Roma, Rm, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.