Evaluation of perioral tissue using advanced videodermoscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to systematically document the characteristics of healthy perioral tissue in young adults aged 20 to 35. Utilizing advanced videodermoscopy, the study focuses on identifying various dermato-mucosal structures, including pores, fine lines, and texture patterns in the perioral region. A total of 40 participants will be assessed to ensure a reliable evaluation of skin characteristics, while controlling for confounding factors such as age, gender, and environmental exposure. The findings are intended to inform future larger-scale studies on oral mucosal disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: Participants must be between 20 and 35 years old
* Health Status: Participants must be in good general health with no known systemic diseases (ASA I)
* Skin Condition: Participants must have clinically healthy skin in the target area, with no history of dermatological conditions such as eczema, psoriasis, or dermatitis
* Consent: Participants must provide written informed consent to participate in the study
* Non-Smoking: Participants should be non-smokers or have quit smoking for at least 12 months
* Exposure: Must not have been recently exposed to treatments affecting the skin in the area of interest (e.g., laser treatments, chemical peels, or topical medications) within the last 3 months

Exclusion Criteria:

* Dermatological Disorders: History of skin diseases (e.g., acne, psoriasis, eczema) or other skin conditions that could interfere with the assessment
* Chronic Illnesses: Presence of chronic systemic conditions (e.g., diabetes, autoimmune diseases) that may affect skin health
* Medications: Current use of medications or treatments that could alter skin characteristics (e.g., corticosteroids, retinoids, immunosuppressants)
* Allergies: Known allergies to topical products used during the examination
* Pregnancy or Lactation: Pregnant or breastfeeding individuals are excluded due to potential skin changes during these periods
* Recent Skin Procedures: Any recent dermatological procedures (e.g., laser therapy, chemical peels) performed within the last 3 months in the area of evaluation
* Excessive Sun Exposure: Individuals with recent excessive sun exposure or sunburns in the target area within the last 2 months
* Non-Compliance: Individuals unwilling or unable to comply with the study procedures

Where it's running

• UOC Clinica Odontoiatrica, Fondazione Policlinico Agostino Gemelli IRCCS
  Roma, Italy Recruiting

Study contacts

• Principal investigator: Massimo Cordaro, MD — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
• Study coordinator: Andrea Camodeca, DMD, MSc
• Email: andrea.camodeca@unicatt.it
• Phone: +39 340 4226798

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.