Comparing surgery and medical treatment for breast cancer that has spread to the liver

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational study aims to compare the effectiveness of liver resection versus medical therapy alone in patients with breast cancer liver metastasis (BCLM). It consists of two phases: a retrospective analysis of patients treated from 1994 to 2018 and an ambispective phase including patients treated from 2018 to 2023. The primary endpoint is to evaluate the 5-year overall survival rates between the two treatment approaches, while secondary endpoints include recurrence rates and post-operative complications. Data will be collected from multiple international centers, focusing on a comprehensive analysis of treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \> 18 years old
* BCLM
* BCLM and extra-hepatic disease
* Any treatment
* Ability to understand and sign the informed consent

Exclusion Criteria:

* Inability to provide the informed consent
* Patient who underwent Best Supportive Care or Palliation

Where it's running

• Fondazione Policlinico Universitario Agostino Gemelli IRCCS
  Rome, Lazio, Italy Recruiting

Study contacts

• Study coordinator: Amelia Mattia, MD
• Email: amelia.mattia01@icatt.it
• Phone: +390453015

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.