Using a prediction algorithm to prevent low blood pressure during abdominal aortic aneurysm repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial will enroll patients scheduled for elective abdominal aortic aneurysm repair and randomize them to two groups. The control arm will receive hemodynamic optimization based on standard cardiovascular parameters displayed on the Hemosphere platform. The interventional arm will use the Hypotension Prediction Index to prompt proactive therapy aimed at preventing hypotension. The study is conducted at a single center and will compare intraoperative hemodynamic stability and related outcomes between the two approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* planned aortic surgery acceptance of written informed consent

Exclusion Criteria:

* body mass index \> 35 kg/m2
* atrial fibrillation
* urgent surgery
* end-stage renal disease
* pregnancy
* refusal of the consent

Where it's running

• Fondazione Policlinico Universitario Agostino Gemelli
  Rome, Rm, Italy Recruiting

Study contacts

• Study coordinator: Andrea Russo, medical doctor
• Email: andrea.russo@policlinicogemelli.it
• Phone: +39-0630153160

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery

  This study tests how blood pressure, heart rate, and oxygen levels change during bimaxillary orthognathic surgery and whether the trigeminocardiac reflex occurs.

  Recruiting Kırıkkale University · Kirikkale, Kırıkkale · NCT07726251

• Sedation with dexmedetomidine, propofol, or both during cataract surgery

  This project will test whether dexmedetomidine, propofol, or their combination (each given with fentanyl) provides the best sedation, safety, and surgeon satisfaction for adults having cataract surgery.

  Recruiting Saint-Joseph University · Beirut · NCT07556133

• MRI-derived Pressure Ratio (MPR) to predict stroke risk in intracranial atherosclerosis (ICAS)

  This study will test whether a new MRI-derived pressure ratio (MPR) can help predict 1-year stroke risk in adults (18–80) with 50–99% intracranial atherosclerotic stenosis in the anterior circulation.

  Recruiting Xuanwu Hospital, Beijing · Beijing, Xicheng District · NCT07309718

• Using a suprasternal ultrasound to see if heart filling changes help guide fluids in kids undergoing surgery

  This observational study tests whether measuring aortic flow with a suprasternal Doppler can predict which pediatric patients will benefit from fluid adjustments during surgery.

  Recruiting University Hospital, Lille · Lille · NCT07099664

• Three goal-directed hemodynamic strategies for fluid management during major abdominal cancer surgery

  This trial tests whether three goal-directed fluid-management approaches (FLOTRAC, the Hypotension Prediction Index, and HPI combined with Assisted Fluid Management) help people aged 65 and older having major abdominal cancer surgery keep blood pressure stable and reduce complications.

  Recruiting at 3 sites ASST Sette Laghi · Bergamo, Italy and 2 other locations · NCT06871150

• Investigating fluid responsiveness and venous congestion in critically ill patients during volume expansion

  This study is testing how well critically ill patients respond to extra fluids and if they have too much fluid in their veins during treatment in the ICU.

  Recruiting at 3 sites Bicetre Hospital · Guangzhou, Guangdong and 2 other locations · NCT06772038

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.