Managing asymptomatic carotid stenosis to prevent strokes
The Management of Asymptomatic Carotid Stenosis: Monocentric Experience
This study looks at whether surgery to clear blocked neck arteries can help older patients with no symptoms avoid strokes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma, RM) |
| Trial ID | NCT06882954 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with asymptomatic carotid stenosis, which is defined as having no hemispheric or retinal symptoms in the six months prior to diagnosis. The study aims to evaluate the outcomes of carotid endarterectomy (CEA) and stenting procedures in patients with significant stenosis, specifically those over 80% blockage. By analyzing retrospective data from a single medical center, the study seeks to clarify the benefits and risks associated with surgical interventions in this patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with asymptomatic carotid stenosis greater than 80% and specific ultrasound characteristics indicating potentially unstable plaque.
Not a fit: Patients with symptomatic carotid artery stenosis will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the most effective management strategies for preventing strokes in patients with asymptomatic carotid stenosis.
How similar studies have performed: While there have been studies on carotid stenosis management, this specific focus on asymptomatic cases and the evaluation of surgical interventions remains a debated and less explored area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Asymptomatic carotid stenosis * Patient with degree of carotid stenosis greater than 80% measured by the maximum systolic velocity at the site of the stenosis which must have been greater than 250 cm/s * Ultrasound characteristics of a possibly unstable plaque Exclusion Criteria: * Symptomatic carotid artery stenosis
Where this trial is running
Roma, RM
- Fondazione Policlinico Universitario A. Gemelli IRCCS — Roma, Rm, Italy (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.