Education to prevent infections after spleen removal
Official title: Evaluation of an Educational Intervention on Knowledge and Awareness of Infectious Risk in Splenectomized Patients and on Their Satisfaction With Vaccination Management in an Intra-hospital Outpatient Setting.
Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07354893 · Data updated 2026-11-12
See if a targeted educational program for adults who had their spleen removed improves vaccination uptake, awareness of infection risk, and continuity of care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 2 sites (Rome, Lazio and 1 other locations) |
| Status | Recruiting |
| Started | January 13, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | January 13, 2028 |
| Registry record updated | February 2, 2026 |
| Trial ID | NCT07354893 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) who undergo splenectomy at the Gemelli hospital and request or receive an in-hospital vaccination consultation and provide informed consent are ideal candidates.
✕Probably not a fit
Patients splenectomized at other hospitals, minors, those who decline consent, or individuals already fully vaccinated and adherent to prevention measures are unlikely to gain additional benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, observational registry enrolling adults who undergo splenectomy at Fondazione Policlinico Universitario A. Gemelli IRCCS and who consent to an in-hospital vaccination consultation. Clinical, sociodemographic, and vaccination-related data are recorded in a dedicated database, and patient-reported outcomes are collected with structured questionnaires administered before and after a standardized educational intervention. Patients who complete the vaccination pathway are followed longitudinally by outpatient visits or structured telephone interviews to monitor vaccine uptake and schedule completion. Data are pseudonymized and managed according to Good Clinical Practice and applicable data protection regulations.
Why it matters
Potential benefit: If successful, the program could increase timely vaccination and preventive behaviors and thereby reduce the risk of overwhelming post-splenectomy infection.
How similar studies have gone: Post-splenectomy vaccination is proven to reduce OPSI risk and prior interventions in other settings have improved vaccine uptake, but single-center educational registries of this exact design are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (≥18 years old) * Patients splenectomized at FPG for whom a vaccination consultation is requested during hospitalization * Patients who provide signed informed consent to participate in the study and for the processing of personal data for research purposes Exclusion Criteria: * Minor patients * Lack of signed informed consent for participation in the study and for the processing of personal data for research purposes * Patients splenectomized at other healthcare facilities
Where it's running
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Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, Lazio, Italy Recruiting -
Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, Italy Recruiting
Study contacts
- Principal investigator: Laurenti Patrizia, Professor — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Laurenti Patrizia, Professor
- Email: patrizia.laurenti@policlinicogemelli.it
- Phone: 063015.9333
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Laparoscopic splenectomy's effect on liver function in cirrhosis patients
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.