Using AI to improve safety in minimally invasive surgery for uterine cancers

Implementation of Surgical Safety and Intraoperative Metastasis Identification Through Deep Learning: Multicentric Video Collection for Minimally Invasive Sentinel Lymph Node Dissection in Uterine Malignancies

Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06619002

This study is testing if using AI to analyze surgical videos can make minimally invasive surgeries for uterine cancers safer and help doctors spot problems during the operation.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years to 99 Years
SexFemale
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS (other)
Drugs / interventionsradiation
Locations2 sites (Roma and 1 other locations)
Trial IDNCT06619002 on ClinicalTrials.gov

What this trial studies

This study focuses on enhancing surgical safety and identifying intraoperative metastasis in patients undergoing minimally invasive sentinel lymph node dissection for endometrial and cervical cancers. By utilizing deep learning algorithms to analyze surgical videos, the research aims to document and quantify intraoperative events, thereby identifying potential complications and improving surgical outcomes. The study will collect multicentric video data to develop AI tools that can provide real-time decision support during surgeries. This innovative approach seeks to address the limitations of current sentinel lymph node procedures and improve patient management.

Who should consider this trial

Good fit: Ideal candidates for this study are women over 18 years old who are undergoing minimally invasive sentinel lymph node dissection for endometrial or cervical cancers.

Not a fit: Patients with previous pelvic radiotherapy treatments or severe endometriosis may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce surgical complications and improve outcomes for patients with uterine malignancies.

How similar studies have performed: Other studies have shown promise in using AI for surgical video analysis, indicating potential success for this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women undergoing MIS sentinel lymph node dissection for endometrial or cervical cancers
* Availability of video
* Age \>18 years
* Willingness to participate in the study and to provide informed consent

Exclusion Criteria:

* Previous pelvic radiotherapy treatments
* Severe endometriosis or other conditions able to alter the pelvic anatomy

Where this trial is running

Roma and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Endometrial Cancer, Cervical Cancer, Deep Learning, Artificial Intelligence, endometrial cancer, cervical cancer, deep learning, computer vision

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.