Evaluating long-term outcomes in adults with congenital heart disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on adult patients with congenital heart disease who are evaluated at a specialized outpatient clinic. It aims to identify clinical and echocardiographic predictors of adverse events such as death, arrhythmias, and hospitalizations during follow-up. The study will also assess the incidence of specific adverse events and the impact of acquired heart conditions that develop over time. Participants will be monitored during their routine follow-up visits without any additional interventions beyond standard clinical care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients evaluated in our ACHD Outpatient Clinic between January 2014 and December 2026
* Age ≥ 18 years

Exclusion Criteria:

* Patients without congenital heart disease confirmed during the first evaluation
* Impossibility to retrieve information about the first clinical evaluation in our clinic from our electonic datasets
* Follow up shorter than one-year
* Refused consent to participate to the study.

Where it's running

• Fondazione Policlinico Universitario Agostino Gemelli
  Rome, Rm, Italy Recruiting

Study contacts

• Study coordinator: Francesca Graziani, MD, PhD
• Email: francesca.graziani@policlinicogemelli.it
• Phone: 00390630154432

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Heart Institute Biobank and Registry for Adults with Congenital Heart Disease and Related Conditions

  This project will collect blood, tissue samples, and detailed health information from adults (≥16) with congenital heart disease and related heart or vascular conditions to create a resource researchers can use.

  Recruiting Children's Hospital Medical Center, Cincinnati · Cincinnati, Ohio · NCT07477197

• Evaluating cardiac resynchronization therapy effects in adults with congenital heart disease

  This study is trying to see if cardiac resynchronization therapy can help adults with congenital heart disease feel better and improve their heart function.

  Recruiting Leiden University Medical Center · Leiden, South Holland · NCT06969924

• Trauma, PTSD, and resilience in adults living with congenital heart disease

  This project will test whether lifetime experiences related to congenital heart disease are linked to PTSD and whether resilience helps protect adults with CHD.

  Recruiting Dartmouth-Hitchcock Medical Center · Washington D.C., District of Columbia and 2 other locations · NCT06952933

• Evaluating the effectiveness of SGLT2 inhibitors in adults with congenital heart disease

  This study is trying to see if a new type of diabetes medication can help adults with congenital heart disease feel better and manage their heart failure symptoms.

  Recruiting at 11 sites Leiden University Medical Center · Baltimore, Maryland and 10 other locations · NCT06932081

• Identifying noninvasive markers of heart transplant rejection in patients with congenital heart disease

  This study is testing a new blood test to see if it can help detect heart transplant rejection in patients with congenital heart disease without needing a more invasive procedure.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06784440

• Observational study of adults with congenital heart disease

  This study looks at how adults with congenital heart disease are managed at a specialized center to see how their health is doing and what kind of care they need.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06769529

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.