Aortic Diseases and Quality of Life: How Work Ability is Affected
Official title: Impact of Aortic Disease on Patients' Quality of Life and Working Capacity
Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07479186 · Data updated 2026-11-12
This observational study tests how living with aortic diseases affects quality of life, fatigue, mental well-being, and the ability to work in adults aged 18 to 70.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma, RM) |
| Status | Recruiting |
| Started | March 31, 2026 |
| Main results expected | March 31, 2028 |
| Study ends | June 30, 2028 |
| Registry record updated | June 9, 2026 |
| Trial ID | NCT07479186 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–70 with a confirmed aortic disease who are under the care of the Vascular Surgery unit at Gemelli IRCCS.
✕Probably not a fit
Individuals outside the 18–70 age range or without a confirmed aortic disease, or those with recent unrelated acute events that confound return-to-work assessment, may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This longitudinal observational study examines health-related quality of life, fatigue, psychological well-being, and work ability in adults with aortic diseases. Participants are adults aged 18–70 receiving care at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS. The study aims to provide objective data to support occupational risk evaluation and promote interdisciplinary management that combines medical care with psychological and social support. Data collection will focus on patient-reported outcomes and functional status to understand how aortic diseases impact daily living and work. Interventions are not part of this study; it observes current care and its effects over time.
Why it matters
Potential benefit: If successful, findings could inform strategies to improve quality of life and preserve work ability for people living with aortic diseases.
How similar studies have gone: While similar work-ability and quality-of-life research exists in related vascular conditions, this study addresses aortic diseases specifically and is building on established patient-reported outcome methodologies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female patients with a confirmed diagnosis of aortic disease under the care of the Complex Operative Unit of Vascular Surgery of the Fondazione Policlinico Universitario Agostino Gemelli IRCCS. * Patients aged between 18 and 70 years. Exclusion Criteria: * Patients younger than 18 years or older than 70 years. * Incomplete diagnostic workup. * Patients who have undergone surgical procedures or experienced concomitant acute events unrelated to the aorta, with a predominant and recent functional impact, that make it impossible to isolate the effect of aortic disease on return to work.
Where it's running
-
Fondazione Policlinico Gemelli IRCCS
Roma, Rm, Italy Recruiting
Study contacts
- Principal investigator: Ivo Iavicoli, Prof — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Ivo Iavicoli, Prof
- Email: ivo.iavicoli@unicatt.it
- Phone: + 39 0630155145
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.