Analyzing miRNAs in COVID-19 patients
Circulating Mi-RNA Associated With Disease Severity and Outcome in COVID-19 Patients
This study is trying to see if certain tiny molecules in the blood can help predict how severe COVID-19 will be and if it might lead to death in adults who have tested positive for the virus.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 49 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma, RM) |
| Trial ID | NCT06881160 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the role of microRNAs (miRNAs) in patients diagnosed with COVID-19, focusing on their association with disease severity and mortality. By analyzing miRNA profiles in individuals confirmed to have SARS-CoV-2 infection, the study seeks to identify potential biomarkers that could help predict clinical outcomes. Participants will be adults aged 18 and older who have tested positive for the virus, while pregnant women will be excluded from the study. The research will be conducted at Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a confirmed diagnosis of SARS-CoV-2 infection.
Not a fit: Patients who are pregnant will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could lead to the identification of biomarkers that help predict the severity of COVID-19, potentially guiding treatment decisions.
How similar studies have performed: While the analysis of miRNAs in relation to COVID-19 is a relatively novel approach, similar studies have shown promise in identifying biomarkers for other diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years * diagnosis of SARS-CoV-2 infection confirmed by molecular testing on nasopharyngeal swabs Exclusion Criteria: * pregnant women
Where this trial is running
Roma, RM
- Fondazione Policlinico Universitario A. Gemelli IRCCS — Roma, Rm, Italy (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.