Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing miRNAs in COVID-19 patients

Official title: Circulating Mi-RNA Associated With Disease Severity and Outcome in COVID-19 Patients

Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06881160 · Data updated 2026-11-12

This study is trying to see if certain tiny molecules in the blood can help predict how severe COVID-19 will be and if it might lead to death in adults who have tested positive for the virus.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment49 (estimated)
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
Academic / other
Locations1 site (Roma, RM)
StatusRecruiting
StartedMarch 1, 2020
Main results expectedDecember 31, 2025
Study endsDecember 1, 2027
Registry record updatedMarch 18, 2025
Trial IDNCT06881160 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with a confirmed diagnosis of SARS-CoV-2 infection.

Probably not a fit

Patients who are pregnant will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the role of microRNAs (miRNAs) in patients diagnosed with COVID-19, focusing on their association with disease severity and mortality. By analyzing miRNA profiles in individuals confirmed to have SARS-CoV-2 infection, the study seeks to identify potential biomarkers that could help predict clinical outcomes. Participants will be adults aged 18 and older who have tested positive for the virus, while pregnant women will be excluded from the study. The research will be conducted at Fondazione Policlinico Universitario A. Gemelli IRCCS in Rome.

Why it matters

Potential benefit: If successful, this study could lead to the identification of biomarkers that help predict the severity of COVID-19, potentially guiding treatment decisions.

How similar studies have gone: While the analysis of miRNAs in relation to COVID-19 is a relatively novel approach, similar studies have shown promise in identifying biomarkers for other diseases.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years
* diagnosis of SARS-CoV-2 infection confirmed by molecular testing on nasopharyngeal swabs

Exclusion Criteria:

* pregnant women

Where it's running

  • Fondazione Policlinico Universitario A. Gemelli IRCCS
    Roma, Rm, Italy
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.