Evaluating outcomes in gastric cancer patients before and after a Tumor Board implementation
Gastric Cancer' Textbook Oncological Outcome and Tumor Board Performance - The Experience of a High-volume Italian University Hospital
This study is trying to see if having a team of experts work together improves the surgery and treatment results for people with gastric cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Rome, IT) |
| Trial ID | NCT06923449 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare surgical and oncologic outcomes in gastric cancer patients before and after the establishment of a Multidisciplinary Tumor Board at Fondazione Policlinico Gemelli. It will assess the Textbook Outcome (TO) and Textbook Oncological Outcome (TOO) of patients undergoing surgical treatment with curative intent. The study will analyze data from 2018 to the present to evaluate the impact of the Tumor Board on patient outcomes, including treatment allocation and adherence to guidelines. The hypothesis is that the implementation of the Tumor Board will lead to improved outcomes for gastric cancer patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with a confirmed diagnosis of gastric adenocarcinoma who are surgical candidates.
Not a fit: Patients with non-adenocarcinoma histologies, those requiring emergency treatment, or those under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of care and outcomes for patients with gastric cancer.
How similar studies have performed: Previous studies have shown that structured multidisciplinary approaches can improve surgical outcomes in cancer care, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * pathology-confirmed diagnosis of gastric adenocarcinoma * age 18 years or older * surgical candidates with curative intent Exclusion Criteria: * Endoscopic Mucosal Resection (EMR) or Endoscopic Submucosal Dissection (ESD) * previous EMR or ESD (salvage surgery) * histologies other than adenocarcinoma (no squamous cell carcinomas, GISTs, sarcomas, lymphomas, etc) * unsufficient staging (unclear clinical stage at diagnosis) * emergency presentation (obstrucetd, significantly bleeding, perforated gastric cancer) * synchronous tumors affecting survival * pregnant patients * age \<18years
Where this trial is running
Rome, IT
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Rome, It, Italy (Recruiting)
Study contacts
- Principal investigator: Alberto Biondi, Prof. — Fondazione Policlinico Agostino Gemelli IRCCS
- Study coordinator: Laura Antolino, MD, PhD
- Email: laura.antolino@gmail.com
- Phone: +393470409876
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.