Clinical trial Recruiting at 1 site Interventional Ages 70 and up

Preoperative Geriatric Assessment to Guide Hepatectomy in Older Adults

Official title: Impact of Preoperative Oncogeriatric Assessment in Elderly Patients Undergoing Surgery for Hepatectomy

Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07537569 · Data updated 2026-11-12

Aging patients planning liver surgery will be tested to see if a comprehensive geriatric assessment helps tailor perioperative care.

More Hepatectomy trials

Quick facts

Study typeInterventional
Ages70 Years and up
SexAll
Enrollment242 (estimated)
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
Academic / other
Locations1 site (Roma, RM)
StatusRecruiting
StartedApril 9, 2026
Main results expectedApril 2029
Study endsSeptember 2029
Registry record updatedSeptember 10, 2026
Trial IDNCT07537569 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 70 years or older with hepatic malignancies requiring hepatectomy and deemed eligible for curative surgery by a multidisciplinary team.

Probably not a fit

Patients with advanced disease, severe comorbidity limiting surgery, or significant cognitive impairment may not benefit from the CGA-guided approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses a comprehensive geriatric assessment before liver resection to identify frailty, comorbidity, and functional status in patients aged 70 and older with hepatic malignancies. The goal is to inform perioperative planning and optimize safety and recovery. Participants must be candidates for curative hepatectomy and able to consent, with the CGA guiding multidisciplinary care decisions. The study is conducted at a single Italian center and aims to bridge geriatric medicine and surgical oncology.

Why it matters

Potential benefit: If successful, CGA-guided perioperative planning could improve safety and recovery for older patients undergoing hepatectomy.

How similar studies have gone: Prior research in related surgical settings suggests CGA can inform perioperative care, but application specifically to hepatectomy in the elderly is evolving.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged ≥ 70 years
* Diagnosed hepatic malignancies requiring hepatectomy
* Eligible for curative surgery as determined by multidisciplinary team
* Ability to provide informed consent.

Exclusion Criteria:

* Ineligibility for surgery due to advanced disease or severe comorbidities
* Severe cognitive impairment (MMSE score \< 18)
* Refusal to participate

Where it's running

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS
    Roma, Rm, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Pain management plan implementation for major open abdominal surgeries

    This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.

    Recruiting National and Kapodistrian University of Athens · Athens, Athens · NCT07901582

  • Remimazolam vs. Propofol for Maintaining Anesthesia During Major Liver Resection

    This study tests whether remimazolam keeps blood pressure steadier than propofol during major liver surgery in adults.

    Recruiting Phase 4 Beijing Tsinghua Chang Gung Hospital · Beijing, Beijing Municipality · NCT07789275

  • Methylprednisolone Before Major Liver Surgery

    This trial tests whether giving methylprednisolone before major liver surgery helps reduce postoperative complications like infections and long hospital stays for adults having hepatectomy.

    Recruiting at 3 sites Phase 3 Memorial Sloan Kettering Cancer Center · Chicago, Illinois and 18 other locations · NCT07507643

  • AI prediction of liver cancer returning after surgery

    This study will test whether an AI program can identify people with early-stage liver cancer who are likely to have the cancer come back within two years after surgery.

    Recruiting Tongji Hospital · Wuhan, Hubei · NCT07062380

  • Evaluating laparoscopic right hemihepatectomy for liver cancer

    This study is testing if a less invasive liver surgery for cancer can be safer and lead to better recovery than traditional surgery for people with liver cancer.

    Recruiting West China Hospital · Chengdu, Sichuan · NCT06950827

  • A program to assess and promote health in older adults

    This study is testing a new program where university students work with older adults to check their health and promote better living, helping both groups learn from each other.

    Recruiting University of Vic - Central University of Catalonia · Vic, Barcelona · NCT06890325

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.