Preoperative Geriatric Assessment to Guide Hepatectomy in Older Adults
Official title: Impact of Preoperative Oncogeriatric Assessment in Elderly Patients Undergoing Surgery for Hepatectomy
Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT07537569 · Data updated 2026-11-12
Aging patients planning liver surgery will be tested to see if a comprehensive geriatric assessment helps tailor perioperative care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 70 Years and up |
| Sex | All |
| Enrollment | 242 (estimated) |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma, RM) |
| Status | Recruiting |
| Started | April 9, 2026 |
| Main results expected | April 2029 |
| Study ends | September 2029 |
| Registry record updated | September 10, 2026 |
| Trial ID | NCT07537569 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 70 years or older with hepatic malignancies requiring hepatectomy and deemed eligible for curative surgery by a multidisciplinary team.
✕Probably not a fit
Patients with advanced disease, severe comorbidity limiting surgery, or significant cognitive impairment may not benefit from the CGA-guided approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study uses a comprehensive geriatric assessment before liver resection to identify frailty, comorbidity, and functional status in patients aged 70 and older with hepatic malignancies. The goal is to inform perioperative planning and optimize safety and recovery. Participants must be candidates for curative hepatectomy and able to consent, with the CGA guiding multidisciplinary care decisions. The study is conducted at a single Italian center and aims to bridge geriatric medicine and surgical oncology.
Why it matters
Potential benefit: If successful, CGA-guided perioperative planning could improve safety and recovery for older patients undergoing hepatectomy.
How similar studies have gone: Prior research in related surgical settings suggests CGA can inform perioperative care, but application specifically to hepatectomy in the elderly is evolving.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥ 70 years * Diagnosed hepatic malignancies requiring hepatectomy * Eligible for curative surgery as determined by multidisciplinary team * Ability to provide informed consent. Exclusion Criteria: * Ineligibility for surgery due to advanced disease or severe comorbidities * Severe cognitive impairment (MMSE score \< 18) * Refusal to participate
Where it's running
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, Rm, Italy Recruiting
Study contacts
- Principal investigator: Felice Giuliante, MD — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Chiara Schipa, MD
- Email: chiara.schipa@policlinicogemelli.it
- Phone: +39 0630154386
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.