Condition

Childhood Cancer clinical trials and research

• 28Clinical trials
• 64NIH research projects
• 11Countries

Newest Childhood Cancer clinical trials

All recruiting trials (28)

• Community-led, family-centered communication for Hispanic childhood cancer survivors

  This study tests a family-focused communication approach to help young Hispanic adult survivors, their families, and clinicians talk more effectively about survivorship care.

  Recruiting Stanford University · Palo Alto, California · NCT07606443

• Blood biomarkers for treatment-related brain injury in children with brain tumors

  This project will test whether blood plasma biomarkers can show treatment-related brain injury in children with primary brain tumors by comparing those who receive radiotherapy, those who do not, and healthy children of the same age and sex.

  Recruiting Uppsala University · Uppsala · NCT07381959

• At-home light therapy for chemo-related nerve pain in childhood cancer survivors

  This study tests whether a six-week at-home light therapy program can help childhood cancer survivors who have chemotherapy-induced peripheral neuropathy.

  Recruiting at 2 sites Yale University · New Haven, Connecticut and 1 other locations · NCT07019259

• Understanding the needs of siblings of children with cancer

  This study looks at the emotional struggles of siblings of kids with cancer to see how they feel and what support they need during this tough time.

  Recruiting Ersta Sköndal University College · Stockholm · NCT06854822

• Cognitively engaging exercise to boost thinking skills in children and teens with cancer

  This trial tests whether mentally challenging physical activity can improve thinking skills and self-control (executive functions) in children and adolescents undergoing cancer treatment.

  Recruiting University of Bern · Bern · NCT06839794

• Examining muscle function in survivors of childhood leukemia

  This study is trying to see how cancer treatment affects muscle strength and function in survivors of childhood leukemia compared to healthy kids.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT06819475

• Online program to support caregivers of young childhood cancer survivors

  This study is testing an online program to see if it can help caregivers of young childhood cancer survivors feel less stressed and better prepare their kids for school.

  Recruiting Nationwide Children's Hospital · Columbus, Ohio · NCT06769334

• Remote diagnosis of heart issues in childhood cancer survivors

  This study is testing if a new wrist biosensor can help find heart problems in childhood cancer survivors more easily than regular check-ups.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT06747910

• Improving heart health through nutrition for childhood cancer survivors

  This study is testing a nutrition program to see if it can help childhood cancer survivors improve their heart health.

  Recruiting at 2 sites Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06609473

• Assessing long-term dental effects of chemotherapy in childhood cancer survivors

  This study looks at the long-term dental health of childhood cancer survivors who had chemotherapy to see if they have more dental problems compared to kids who didn’t have cancer.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Brussels · NCT06517927

• Targeted therapies for childhood and adolescent cancer

  This study is testing if new targeted treatments based on the genetic makeup of tumors can help kids and teens with cancer feel better and improve their chances of recovery.

  Recruiting at 12 sites Phase 1/2 Australian & New Zealand Children's Haematology/Oncology Group · Newcastle, New South Wales and 13 other locations · NCT06208657

• Evaluating kidney and blood pressure outcomes in childhood cancer survivors

  This study is trying to see how common kidney problems and high blood pressure are in childhood cancer survivors a few years after their treatment.

  Recruiting The Hospital for Sick Children · Toronto, Ontario · NCT06153147

• Freezing testicular tissue to help preserve fertility in young boys with cancer

  This study tests if freezing testicular tissue from young boys with cancer can help them preserve their ability to have children later on.

  Recruiting University of Edinburgh · Edinburgh, Lothian · NCT06063551

• A tool to help young cancer patients manage their symptoms

  This study is testing a new computer tool to help young cancer patients better manage their symptoms during treatment.

  Recruiting at 4 sites Virginia Commonwealth University · Kansas City, Missouri and 4 other locations · NCT05958316

• Investigating cognitive impairment in young cancer patients during and after chemotherapy

  This study is testing how chemotherapy affects memory and attention in children and young adults with cancer to better understand their cognitive challenges during and after treatment.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT05840575

• Cannabinoids in Pediatric Cancer: Tolerability in Children

  This trial tests whether cannabis-based extracts with different THC:CBD ratios are tolerable for children with cancer across three Canadian hospitals.

  Recruiting at 3 sites Phase 1/2 University of Manitoba · Vancouver, British Columbia and 2 other locations · NCT05754840

• Screening for sensory deficits in childhood cancer survivors

  This study is trying to find a better way to check for sensory problems in childhood cancer survivors by using their treatment history to identify who needs testing.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT05582551

• Precision medicine for children with cancer

  This study is testing if personalized medicine can improve treatment and outcomes for children with different types of cancer in Australia and New Zealand.

  Recruiting at 10 sites Australian & New Zealand Children's Haematology/Oncology Group · Adelaide and 10 other locations · NCT05504772

• Assessing late effects in childhood cancer survivors in Aarau, Switzerland

  This study looks at the long-term health effects that childhood cancer survivors experience after their treatment to help improve their follow-up care.

  Recruiting Kantonsspital Aarau · Aarau · NCT04811794

• Long-term health effects in childhood cancer survivors

  This study looks at the long-term health effects that childhood cancer survivors in Switzerland may face as they grow up to help improve their care and quality of life.

  Recruiting at 3 sites University of Bern · Basel and 2 other locations · NCT04732273

• Identifying genetic risks for complications in childhood cancer patients in Switzerland

  This study is trying to find out if certain genetic differences can help explain the complications that childhood cancer patients in Switzerland might face after their treatment.

  Recruiting University Hospital, Geneva · Geneva · NCT04702321

• Aftercare for childhood cancer survivors in Switzerland

  This study is trying to find out how childhood cancer survivors in Switzerland feel about their follow-up care as they transition from pediatric to adult healthcare, so they can improve support for them.

  Recruiting at 3 sites Kantonsspital Aarau · Aarau and 2 other locations · NCT04284189

• Evaluating heart health in adult survivors of childhood cancer

  This study is testing if a new heart imaging technique can find heart problems earlier in adult survivors of childhood cancer who had treatments that might have harmed their hearts.

  Recruiting at 5 sites University of Bern · Basel, Canton of Basel-City and 5 other locations · NCT03790943

• Measuring heart calcium levels in adults treated for childhood cancer

  This study is testing if adults who had radiation therapy for childhood cancer have higher heart calcium levels compared to others, to see if the treatment affects their heart health.

  Recruiting at 3 sites Gustave Roussy, Cancer Campus, Grand Paris · Villejuif, Val De Marne and 2 other locations · NCT03604627

• Investigating long-term effects of childhood cancer on survivors

  This study is trying to learn about the long-term health and quality of life of people who survived childhood cancer to help improve their care as they grow older.

  Recruiting University of Bern · Bern, Canton of Bern · NCT03297034

• Preserving fertility in boys undergoing cancer treatment

  This study is testing a way to help young boys with cancer keep their ability to have children in the future by freezing their testicular tissue before treatment.

  Recruiting at 3 sites University Hospital, Geneva · Basel and 2 other locations · NCT03180918

• Epidemiological study of childhood cancer in Shanghai

  This study is looking at the rates of childhood cancer in Shanghai to see how many kids are getting sick, how they are doing, and what types of cancer they have.

  Recruiting Children's Cancer Group, China · Shanghai, Shanghai Municipality and 1 other locations · NCT02959086

• Collecting data on childhood cancer patients

  This study is trying to gather important long-term health information from children who have been treated for cancer to help improve their care and monitor any lasting effects.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT00684580

NIH-funded research (newest 40 of 64)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Genomics of childhood ALL across global populations

  A wide-ranging study looks at how inherited genetics influence the risk of childhood acute lymphoblastic leukemia around the world.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11608541

• Genomics of childhood ALL across diverse populations

  A large international study will look at why children everywhere get acute lymphoblastic leukemia and how genetics may influence risk.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11608540

• Sustainability of pediatric early warning systems to protect children with cancer in low-resource hospitals

  Aimed at keeping children with cancer safer in low-resource hospitals by studying how a simple warning and action system (PEWS) is being adopted and kept going across multiple hospitals.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11540216

• Targeting retrotransposons to help kids with hard-to-treat cancers like neuroblastoma

  Aims to repurpose safe antiviral drugs to block retrotransposons in children with relapsed or refractory neuroblastoma to improve outcomes.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11535292

• Better identifying late health problems in adult survivors of childhood cancer

  This project uses computer learning with clinic exams, medical records, genetics, and survey answers to more accurately find conditions like diabetes, high blood pressure, and heart problems in adults who survived childhood cancer.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11471611

• Community-led program to improve quality of life for Spanish-speaking families caring for a child with cancer

  A family-centered, culturally responsive program aims to support Spanish-speaking caregivers of children with cancer and improve their quality of life.

  NIH research University of California-Irvine · Irvine, United States · NIH-11450084

• Strategies to Find and Reconnect Adolescent and Young Adult Cancer Survivors to Adult Follow-Up Care

  A nationwide effort to locate and re-engage young people who survived childhood cancer so they can keep receiving important follow-up care.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11442992

• New and better ways to measure kids' exposure to air pollution and traffic

  This project looks at how traffic-related air pollution and green space around homes may affect cancer risk in children and uses advanced exposure measurements to better understand these links.

  NIH research University of North Texas · Denton, United States · NIH-11422688

• Using ECG and AI to find childhood cancer survivors at risk for late cardiomyopathy

  This project uses routine ECG tracings plus artificial intelligence to spot childhood cancer survivors who may develop heart muscle disease years later.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11417087

• Strategies to improve how teams communicate in low-resource kids’ cancer hospitals

  A multi-hospital effort will test ways to strengthen teamwork and communication to protect children with cancer in settings with limited resources.

  NIH research Washington University · Saint Louis, United States · NIH-11415632

• Targeting retrotransposons to help kids with hard-to-treat cancer

  A pediatric cancer research grant explores using existing antiviral drugs to help children with relapsed neuroblastoma by turning off retrotransposons that drive cancer growth.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11415610

• Genomics of childhood acute lymphoblastic leukemia across global populations

  This grant studies how inherited genes influence the risk of childhood ALL around the world to understand why some groups are more affected.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11413497

• STRENGTH: Time-restricted eating to reduce cardiometabolic risk in childhood cancer survivors

  A program tests whether time-restricted eating can lower heart and diabetes risks for adults who survived childhood cancer.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11412636

• Childhood acute lymphoblastic leukemia genetics around the world

  This project compares inherited genetic differences in children with and without acute lymphoblastic leukemia across many countries to learn who is at higher risk.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11407900

• Genetics of childhood acute lymphoblastic leukemia

  This project looks at how inherited genes affect the risk of acute lymphoblastic leukemia in children from many countries and ancestry groups.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11407899

• Using antiviral drugs to target jumping DNA in hard-to-treat childhood neuroblastoma

  Researchers are looking at whether common antiviral drugs can block jumping DNA elements to help children with relapsed or refractory high-risk neuroblastoma.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11401311

• Family-centered communication help for young adult survivors of childhood cancer

  A K08 grant to develop and pilot a tailored family-centered communication program to help young adult survivors of childhood cancer manage their ongoing care.

  NIH research Stanford University · Stanford, United States · NIH-11396251

• Predicting Late Effects in Childhood Cancer Survivors Using Patient-Generated Health Data

  This grant tests a mobile health approach to track symptoms, activity, sleep, and heart rate in adults who survived childhood cancer to predict future health problems and guide care.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11377608

• Childhood Cancer, Environment, and Kids’ Perceptions of Weather-Related Risks

  A pediatric cancer-focused study is exploring how environmental events like extreme weather affect kids with cancer and how families perceive and cope with these risks.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11374404

• Keeping early-warning systems working in low-resource hospitals to protect children with cancer

  This project finds ways hospitals in low-resource settings can keep using an early-warning system that spots when children with cancer are getting worse so more kids survive.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11372794

• Digital self-management and peer mentoring to help childhood cancer survivors transition to adult care

  A digital, mentor-supported program helps young survivors manage their health as they move from pediatric to adult follow-up care.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11370853

• Race-specific heart risk tools for African American childhood cancer survivors

  Aims to create and validate heart-disease risk models specifically for African American survivors of childhood cancer who were treated with heart-damaging therapies.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11326331

• Childhood cancer survivorship resource

  This project gathers long-term health data and blood samples from people who survived cancer as children to learn how treatment affects health later in life.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11296842

• How Medicaid affects care for adults who survived childhood cancer

  This project looks at how Medicaid shapes healthcare experiences for adults who had cancer as children.

  NIH research Emory University · Atlanta, United States · NIH-11251259

• Personalized heart risk prediction for childhood cancer survivors

  This project helps predict and lower the chance of heart disease for people who survived cancer as children.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11212382

• Improving communication in low-resource children's cancer hospitals

  This project will try a package of team communication tools and practices to help hospital staff better coordinate care for children with cancer in hospitals that have limited resources.

  NIH research Washington University · Saint Louis, United States · NIH-11195619

• Shared genetic causes of childhood cancer and birth defects

  We are combining genetic data from children with cancers and structural birth defects to look for common genetic signals that might explain why they happen together.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11195033

• Using Your Health Data to Understand Childhood Cancer Recovery

  This project collects health information directly from adult survivors of childhood cancer to better understand and predict their long-term health.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11192249

• Time‑restricted eating to lower heart and metabolic risk in childhood cancer survivors

  This project sees if limiting daily eating to an 8–10 hour window helps adult survivors of childhood cancer improve weight, blood sugar, and heart health.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11177899

• Bridging cancer center and local doctor care to help childhood cancer survivors keep up with follow-up

  A telehealth education program, tailored patient-portal messages, and coordinated outreach to primary care doctors to help childhood cancer survivors stay on track with recommended long-term follow-up care.

  NIH research Georgetown University · Washington, United States · NIH-11166590

• How personal, cultural, and neighborhood factors shape follow-up care for Asian childhood cancer survivors

  This project looks at how a survivor's background, culture, and neighborhood influence long-term follow-up care for Asian and Asian American adults who had cancer as children.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11166334

• How inherited genes affect childhood acute lymphoblastic leukemia worldwide

  This project looks at inherited gene differences that relate to the risk of children developing acute lymphoblastic leukemia across many countries.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11140437

• Creating a national registry for childhood cancer data

  This study is creating a big database to gather and share important information about childhood cancers, like genetic details and treatment histories, so that kids with cancer and their families can get better treatment options and help track their health over time.

  NIH research North American Assn/central Cancer Reg · Springfield, United States · NIH-11126505

• Helping young adult cancer survivors manage their health as they move to adult care

  This project helps young adult survivors of childhood cancer learn to manage their health and connect with peer mentors as they transition to adult healthcare.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11110486

• Repurposing antiviral drugs to block mobile DNA in high‑risk neuroblastoma

  Researchers are looking at whether antiviral drugs called NRTIs can stop active mobile DNA elements in tumors to help children whose high‑risk neuroblastoma has come back or not responded to treatment.

  NIH research Roswell Park Cancer Institute Corp · Buffalo, United States · NIH-11106018

• Creating heart disease risk models for African American childhood cancer survivors

  This study is looking to find out how to better predict heart problems in African American childhood cancer survivors who received certain treatments, so they can catch any issues early and help keep their hearts healthy.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11085246

• Investigating heart problems caused by cancer treatment in childhood cancer survivors

  This study is looking at how cancer treatments from childhood might affect heart health later on, and it's for people who survived childhood cancer to help us learn more about the connection between those treatments and heart issues.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11083646

• Understanding how childhood cancer survivors age faster than their peers

  This study is looking at how childhood cancer can make survivors age faster than usual, by checking certain markers in their blood, and it aims to find out what factors affect their health so we can help them live healthier lives.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11082410

• Understanding Heart Risks for Childhood Cancer Survivors

  This work aims to create better tools to understand and prevent heart problems in people who had cancer as children.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11075286

• Identifying childhood cancer survivors at risk for heart problems using AI and ECG data.

  This study is working on a smart computer program that looks at heart test results to help find childhood cancer survivors who might be at risk for heart problems later on, so they can get the care they need to stay healthy.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11059172

Related topics

Quick answers

How many Childhood Cancer clinical trials are recruiting right now?

28, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (9 trials), Switzerland (8 trials), Canada (3 trials), Australia (2 trials), Sweden (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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