Predicting Late Effects in Childhood Cancer Survivors Using Patient-Generated Health Data
Official title: Patient-Generated Health Data to Predict Childhood Cancer Survivorship Outcomes
Funded at St. Jude Children's Research Hospital · NIH-11377608 · Data updated 2026-11-12
This grant tests a mobile health approach to track symptoms, activity, sleep, and heart rate in adults who survived childhood cancer to predict future health problems and guide care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project start | July 5, 2021 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $751,475 |
| NIH project number | 5R01CA258193-05 |
| Project ID | NIH-11377608 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (18 years or older) who survived childhood cancer and are at least five years post-diagnosis.
✕Less likely to help
Individuals who do not use mobile health devices or have conditions making wearable data unreliable may see limited benefit.
What this research studies
Young adults who survived childhood cancer would have their daily health data collected through a mobile app for three months. The researchers will build and test models that use these data to forecast risks for late health effects and poorer quality of life. The goal is to personalize monitoring and early interventions to prevent or lessen complications as survivors age. The study will recruit 620 adult survivors from the St. Jude Lifetime Cohort who are at least 18 years old at enrollment and more than five years from their diagnosis. Outcomes include improved prediction of adverse late effects and enhanced survivorship care planning.
Why it matters
Potential benefit: If successful, this approach could enable personalized monitoring and earlier interventions to reduce late-effects and improve long-term quality of life for childhood cancer survivors.
How similar studies have gone: Previous work supports the feasibility of using patient-generated health data to predict health outcomes, with growing evidence for its value in survivorship care.
Where this research is happening
-
St. Jude Children's Research Hospital
Memphis, United States Active
Researchers
- Principal investigator: Huang, I-Chan — St. Jude Children's Research Hospital
- Study coordinator: Huang, I-Chan
Related research
Other NIH-funded projects on the same topics.
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Childhood cancer survivorship resource
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Using Your Health Data to Understand Childhood Cancer Recovery
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Bridging cancer center and local doctor care to help childhood cancer survivors keep up with follow-up
A telehealth education program, tailored patient-portal messages, and coordinated outreach to primary care doctors to help childhood cancer survivors stay on track with recommended long-term follow-up care.
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Improving care for childhood cancer survivors through community partnerships
This study is all about helping kids who have survived cancer get the follow-up care they need by using telehealth to connect them with their doctors, making it easier for them to understand and manage their health after treatment.
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Using patient-generated health data to predict outcomes for childhood cancer survivors
This study is looking at childhood cancer survivors to understand their long-term health needs better, so we can create personalized plans to help them stay healthy and improve their quality of life.
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How distance affects care for childhood cancer survivors
This study looks at how far childhood cancer survivors, ages 0-20, have to travel to get specialized care and how that distance affects their health and access to medical help, especially for those who might be facing more challenges.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.