Genomics of childhood acute lymphoblastic leukemia across global populations
Official title: Genomics of childhood acute lymphoblastic leukemia in the Childhood Cancer and Leukemia International Consortium
Funded at University of Minnesota · NIH-11413497 · Data updated 2026-11-12
This grant studies how inherited genes influence the risk of childhood ALL around the world to understand why some groups are more affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 22, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $365,809 |
| NIH project number | 5R01CA266253-05 |
| Project ID | NIH-11413497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and young people diagnosed with acute lymphoblastic leukemia and their families, particularly across diverse ancestral backgrounds.
✕Less likely to help
Individuals without ALL or without a family history of ALL are unlikely to benefit directly.
What this research studies
All children diagnosed with acute lymphoblastic leukemia have different genetic backgrounds that may affect their risk. The project uses international collaboration to study inherited genetic factors and how they relate to ALL risk in diverse populations. Findings could point to why ALL occurs more in some groups and how to tailor prevention and treatment in the future. The work aims to translate genetic insights into improved care for children with ALL globally.
Why it matters
Potential benefit: Better understanding of genetic risk factors could lead to earlier detection and more personalized treatment approaches for children with ALL.
How similar studies have gone: Previous GWAS studies have identified multiple variants associated with ALL risk, supporting the potential for meaningful discoveries in this project.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Spector, Logan G. — University of Minnesota
- Study coordinator: Spector, Logan G.
Related research
Other NIH-funded projects on the same topics.
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Genomics of childhood ALL across global populations
A wide-ranging study looks at how inherited genetics influence the risk of childhood acute lymphoblastic leukemia around the world.
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Genomics of childhood ALL across diverse populations
A large international study will look at why children everywhere get acute lymphoblastic leukemia and how genetics may influence risk.
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Childhood acute lymphoblastic leukemia genetics around the world
This project compares inherited genetic differences in children with and without acute lymphoblastic leukemia across many countries to learn who is at higher risk.
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Genetics of childhood acute lymphoblastic leukemia
This project looks at how inherited genes affect the risk of acute lymphoblastic leukemia in children from many countries and ancestry groups.
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How inherited genes affect childhood acute lymphoblastic leukemia worldwide
This project looks at inherited gene differences that relate to the risk of children developing acute lymphoblastic leukemia across many countries.
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Understanding the genetics of childhood acute lymphoblastic leukemia
This study is looking at how certain genes might make kids aged 0-14 more likely to get acute lymphoblastic leukemia (ALL), and it hopes to find ways to better prevent and treat the disease by understanding how different backgrounds can affect this risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.