Investigating heart problems caused by cancer treatment in childhood cancer survivors
Genomics-based Mechanistic Investigation of Cancer-treatment Related Cardiotoxicity among Survivors of Childhood Cancer
This study is looking at how cancer treatments from childhood might affect heart health later on, and it's for people who survived childhood cancer to help us learn more about the connection between those treatments and heart issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11083646 on NIH RePORTER |
What this research studies
This research focuses on understanding how cancer treatments received during childhood can lead to heart disease later in life. It aims to explore the genetic and health behavior factors that contribute to cardiovascular issues among survivors of childhood cancer. By examining various cardiometabolic outcomes, such as obesity and hypertension, the study seeks to identify the mechanisms linking cancer treatment to heart problems. Participants will be involved in assessments that look at their genetic makeup and health history to better understand these risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have survived childhood cancer and are experiencing cardiovascular issues or are at risk for such conditions.
Not a fit: Patients who have not undergone cancer treatment during childhood or those without a history of childhood cancer are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing heart disease in childhood cancer survivors.
How similar studies have performed: Previous research has shown that understanding the genetic factors related to treatment side effects can lead to better health outcomes, indicating potential success for this approach.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Wang, Zhaoming — St. Jude Children's Research Hospital
- Study coordinator: Wang, Zhaoming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.