Long-term health effects in childhood cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The SCCSS-FollowUp is a national, multicenter cohort study aimed at investigating the late effects experienced by childhood cancer survivors in Switzerland. This observational study collects data through clinical examinations, laboratory tests, functional assessments, and questionnaires to understand the prevalence and risk factors associated with these late effects. By standardizing follow-up care and assessing survivors longitudinally, the study seeks to minimize chronic diseases and improve the quality of life for this population. The findings will help inform healthcare strategies for managing the long-term health of childhood cancer survivors.

Why it matters

Who can join: the full rules

This prospective cohort study is based on the Childhood Cancer Registry (ChCR), a national, population-based cancer registry that includes all children and adolescents in Switzerland who were diagnosed with cancer at age 0-20 years. It includes patients diagnosed with leukemia, lymphoma, central nervous system tumors, and malignant solid tumors or Langerhans cell histiocytosis.

Inclusion Criteria:

* Registered in the Childhood Cancer Registry (ChCR) or treated and followed-up in a Swiss pediatric oncology (SPOG) clinic, but not registered in the ChCR because of residency in neighboring countries
* Diagnosed at age 0 - 20 years
* Childhood cancer treatment completed
* All age categories at time of inclusion in the study (children, adolescents, adults)
* Written informed consent

Exclusion criteria:

* Childhood cancer survivors in a palliative or relapsed situation where no follow-up examinations are foreseen.

Where it's running

• University Childen's Hospital Basel
  Basel, Switzerland Recruiting
• University Children's Hospital Bern
  Bern, Switzerland Recruiting
• University Hospital Geneva
  Geneva, Switzerland Recruiting

Study contacts

• Principal investigator: Claudia E Kuehni, MD — Institute of Social and Preventive Medicine, University of Bern
• Study coordinator: Claudia E Kuehni, MD
• Email: claudia.kuehni@unibe.ch
• Phone: +41 31 631 35 07

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.