Long-term health effects in childhood cancer survivors
The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)
University of Bern · NCT04732273
This study looks at the long-term health effects that childhood cancer survivors in Switzerland may face as they grow up to help improve their care and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Sex | All |
| Sponsor | University of Bern (other) |
| Locations | 3 sites (Basel and 2 other locations) |
| Trial ID | NCT04732273 on ClinicalTrials.gov |
What this trial studies
The SCCSS-FollowUp is a national, multicenter cohort study aimed at investigating the late effects experienced by childhood cancer survivors in Switzerland. This observational study collects data through clinical examinations, laboratory tests, functional assessments, and questionnaires to understand the prevalence and risk factors associated with these late effects. By standardizing follow-up care and assessing survivors longitudinally, the study seeks to minimize chronic diseases and improve the quality of life for this population. The findings will help inform healthcare strategies for managing the long-term health of childhood cancer survivors.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who were diagnosed with cancer at age 0-20 years, have completed their treatment, and are currently residing in Switzerland.
Not a fit: Patients who are in a palliative or relapsed situation where no follow-up examinations are planned will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management of late effects in childhood cancer survivors, enhancing their quality of life.
How similar studies have performed: Other studies have successfully investigated late effects in childhood cancer survivors, indicating that this approach is both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
This prospective cohort study is based on the Childhood Cancer Registry (ChCR), a national, population-based cancer registry that includes all children and adolescents in Switzerland who were diagnosed with cancer at age 0-20 years. It includes patients diagnosed with leukemia, lymphoma, central nervous system tumors, and malignant solid tumors or Langerhans cell histiocytosis. Inclusion Criteria: * Registered in the Childhood Cancer Registry (ChCR) or treated and followed-up in a Swiss pediatric oncology (SPOG) clinic, but not registered in the ChCR because of residency in neighboring countries * Diagnosed at age 0 - 20 years * Childhood cancer treatment completed * All age categories at time of inclusion in the study (children, adolescents, adults) * Written informed consent Exclusion criteria: * Childhood cancer survivors in a palliative or relapsed situation where no follow-up examinations are foreseen.
Where this trial is running
Basel and 2 other locations
- University Childen's Hospital Basel — Basel, Switzerland (RECRUITING)
- University Children's Hospital Bern — Bern, Switzerland (RECRUITING)
- University Hospital Geneva — Geneva, Switzerland (RECRUITING)
Study contacts
- Principal investigator: Claudia E Kuehni, MD — Institute of Social and Preventive Medicine, University of Bern
- Study coordinator: Claudia E Kuehni, MD
- Email: claudia.kuehni@unibe.ch
- Phone: +41 31 631 35 07
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Late Effect, Childhood Cancer, Late Effects, Survivor