Time‑restricted eating to lower heart and metabolic risk in childhood cancer survivors
Official title: Decreasing Cardiometabolic Risk in Survivors of Childhood Cancer: Survivors engaged in Time-Restricted EatiNG after THerapy (STRENGTH)
Funded at Sloan-Kettering Inst Can Research · NIH-11177899 · Data updated 2026-11-12
This project sees if limiting daily eating to an 8–10 hour window helps adult survivors of childhood cancer improve weight, blood sugar, and heart health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $744,198 |
| NIH project number | 5R01CA286563-02 |
| Project ID | NIH-11177899 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who had cancer as children (survivors now aged 21 or older), especially those concerned about weight, prediabetes/diabetes risk, or treatment-related cardiometabolic effects, would be ideal candidates.
✕Less likely to help
People who require regular meals for medical reasons (for example, some insulin‑dependent diabetics), pregnant people, or those with active eating disorders may not benefit or may be excluded for safety.
What this research studies
If you join, you'll be asked to limit all calories each day to an 8–10 hour eating window (about 14–16 hours of fasting) and follow study guidance and check-ins. Researchers will measure weight, blood sugar, blood pressure, and markers of inflammation and metabolism over the study period to track changes. Your adherence, symptoms, and safety will be monitored with regular visits, blood tests, and diet/activity logs. The team will compare results to typical eating patterns to learn whether this approach reduces cardiometabolic risk linked to prior cancer treatments.
Why it matters
Potential benefit: If successful, this approach could help survivors lose weight, improve blood sugar control, and lower their long‑term risk of heart disease and diabetes.
How similar studies have gone: Prior time‑restricted eating studies in other groups have shown mixed results—some show meaningful weight and blood sugar improvements and better circadian alignment, while others find little effect—so this approach is promising but not yet proven in childhood cancer survivors.
Where this research is happening
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Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Friedman, Danielle — Sloan-Kettering Inst Can Research
- Study coordinator: Friedman, Danielle
Related research
Other NIH-funded projects on the same topics.
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Strategies to Find and Reconnect Adolescent and Young Adult Cancer Survivors to Adult Follow-Up Care
A nationwide effort to locate and re-engage young people who survived childhood cancer so they can keep receiving important follow-up care.
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Using ECG and AI to find childhood cancer survivors at risk for late cardiomyopathy
This project uses routine ECG tracings plus artificial intelligence to spot childhood cancer survivors who may develop heart muscle disease years later.
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STRENGTH: Time-restricted eating to reduce cardiometabolic risk in childhood cancer survivors
A program tests whether time-restricted eating can lower heart and diabetes risks for adults who survived childhood cancer.
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Family-centered communication help for young adult survivors of childhood cancer
A K08 grant to develop and pilot a tailored family-centered communication program to help young adult survivors of childhood cancer manage their ongoing care.
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Digital self-management and peer mentoring to help childhood cancer survivors transition to adult care
A digital, mentor-supported program helps young survivors manage their health as they move from pediatric to adult follow-up care.
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How Medicaid affects care for adults who survived childhood cancer
This project looks at how Medicaid shapes healthcare experiences for adults who had cancer as children.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.