Time‑restricted eating to lower heart and metabolic risk in childhood cancer survivors
Decreasing Cardiometabolic Risk in Survivors of Childhood Cancer: Survivors engaged in Time-Restricted EatiNG after THerapy (STRENGTH)
This project sees if limiting daily eating to an 8–10 hour window helps adult survivors of childhood cancer improve weight, blood sugar, and heart health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11177899 on NIH RePORTER |
What this research studies
If you join, you'll be asked to limit all calories each day to an 8–10 hour eating window (about 14–16 hours of fasting) and follow study guidance and check-ins. Researchers will measure weight, blood sugar, blood pressure, and markers of inflammation and metabolism over the study period to track changes. Your adherence, symptoms, and safety will be monitored with regular visits, blood tests, and diet/activity logs. The team will compare results to typical eating patterns to learn whether this approach reduces cardiometabolic risk linked to prior cancer treatments.
Who could benefit from this research
Good fit: Adults who had cancer as children (survivors now aged 21 or older), especially those concerned about weight, prediabetes/diabetes risk, or treatment-related cardiometabolic effects, would be ideal candidates.
Not a fit: People who require regular meals for medical reasons (for example, some insulin‑dependent diabetics), pregnant people, or those with active eating disorders may not benefit or may be excluded for safety.
Why it matters
Potential benefit: If successful, this approach could help survivors lose weight, improve blood sugar control, and lower their long‑term risk of heart disease and diabetes.
How similar studies have performed: Prior time‑restricted eating studies in other groups have shown mixed results—some show meaningful weight and blood sugar improvements and better circadian alignment, while others find little effect—so this approach is promising but not yet proven in childhood cancer survivors.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Friedman, Danielle — Sloan-Kettering Inst Can Research
- Study coordinator: Friedman, Danielle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.