STRENGTH: Time-restricted eating to reduce cardiometabolic risk in childhood cancer survivors
Official title: Decreasing Cardiometabolic Risk in Survivors of Childhood Cancer: Survivors engaged in Time-Restricted EatiNG after THerapy (STRENGTH)
Funded at Sloan-Kettering Inst Can Research · NIH-11412636 · Data updated 2026-11-12
A program tests whether time-restricted eating can lower heart and diabetes risks for adults who survived childhood cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $731,806 |
| NIH project number | 5R01CA286563-03 |
| Project ID | NIH-11412636 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who survived childhood cancer, were treated with chest/abdomen/total-body radiation, and have or are at risk for cardiometabolic problems.
✕Less likely to help
Individuals without obesity or cardiometabolic risk factors may see limited or no additional benefit from this approach.
What this research studies
This study enrolls adult survivors of childhood cancer who were treated with chest, abdomen, or total-body radiation and are at higher risk for diabetes and heart problems. Participants will try a daily 14- to 16-hour fasting window while continuing their usual care, with support to monitor adherence and health changes. The researchers will track weight, blood glucose, blood pressure, inflammation, and other cardiometabolic markers over the study period to see if this eating pattern improves risk factors. The goal is to determine if a simple, scalable lifestyle change could reduce long-term health risks for this growing population.
Why it matters
Potential benefit: If successful, participants may experience better weight and metabolic health, potentially lowering future heart disease and diabetes risk.
How similar studies have gone: Prior studies on time-restricted eating show mixed results, but this is one of the first to test it specifically in childhood cancer survivors.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Friedman, Danielle — Sloan-Kettering Inst Can Research
- Study coordinator: Friedman, Danielle
Related research
Other NIH-funded projects on the same topics.
-
Strategies to Find and Reconnect Adolescent and Young Adult Cancer Survivors to Adult Follow-Up Care
A nationwide effort to locate and re-engage young people who survived childhood cancer so they can keep receiving important follow-up care.
-
Using ECG and AI to find childhood cancer survivors at risk for late cardiomyopathy
This project uses routine ECG tracings plus artificial intelligence to spot childhood cancer survivors who may develop heart muscle disease years later.
-
Family-centered communication help for young adult survivors of childhood cancer
A K08 grant to develop and pilot a tailored family-centered communication program to help young adult survivors of childhood cancer manage their ongoing care.
-
Digital self-management and peer mentoring to help childhood cancer survivors transition to adult care
A digital, mentor-supported program helps young survivors manage their health as they move from pediatric to adult follow-up care.
-
How Medicaid affects care for adults who survived childhood cancer
This project looks at how Medicaid shapes healthcare experiences for adults who had cancer as children.
-
Personalized heart risk prediction for childhood cancer survivors
This project helps predict and lower the chance of heart disease for people who survived cancer as children.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.