Assessing long-term dental effects of chemotherapy in childhood cancer survivors
Official title: Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Before the Age of 10
Run by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT06517927 · Data updated 2026-11-12
This study looks at the long-term dental health of childhood cancer survivors who had chemotherapy to see if they have more dental problems compared to kids who didn’t have cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 12 Years to 36 Years |
| Sex | All |
| Enrollment | 142 (estimated) |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Drugs / interventions | Chemotherapy |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | May 3, 2024 |
| Main results expected | May 3, 2026 |
| Study ends | May 3, 2026 |
| Registry record updated | November 19, 2024 |
| Trial ID | NCT06517927 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are childhood cancer survivors diagnosed before the age of 10 who are currently 12 years or older.
✕Probably not a fit
Patients diagnosed and treated for cancer after the age of 10 or those with syndromes affecting dental health may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the prevalence of long-term dental effects in childhood cancer survivors who were diagnosed before the age of 10 and treated with chemotherapy. It will compare the dental health of these survivors to a control group through questionnaires and standard dental examinations. The goal is to identify risks for dental caries and developmental defects, which could inform future prevention and treatment strategies for maintaining healthy oral development in this population.
Why it matters
Potential benefit: If successful, this study could lead to improved dental care strategies for childhood cancer survivors, enhancing their overall quality of life.
How similar studies have gone: While there is limited research specifically targeting this population, similar studies have shown the importance of assessing long-term health effects in cancer survivors, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age below 10 at cancer diagnosis (for the CCS group). * Chemotherapy must have been used to treat the patient (For the CCS group). * The patient is 12 years old or older at the time of the follow-up appointment of the present study Exclusion Criteria: * A patient who was diagnosed and treated after 10 years old. * Patient below 12 years old at time of study recruitment * Patients with syndrome or diseases that involve teeth impairment\* * Pregnant patient * Refusal or inaptitude to undergo dental and radiographic examination
Where it's running
-
Cliniques universitaires Saint-Luc
Brussels, Belgium Recruiting
Study contacts
- Principal investigator: Maëlle De Ville de Goyet — Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Study coordinator: Armand IRAKOZE
- Email: armand.irakoze@uclouvain.be
- Phone: 027645741
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.