Creating heart disease risk models for African American childhood cancer survivors
Developing and validating race-specific cardiomyopathy risk prediction models in African American survivors of childhood cancer
This study is looking to find out how to better predict heart problems in African American childhood cancer survivors who received certain treatments, so they can catch any issues early and help keep their hearts healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11085246 on NIH RePORTER |
What this research studies
This research focuses on developing and validating specific risk prediction models for cardiomyopathy in African American survivors of childhood cancer who have undergone anthracycline chemotherapy or chest-directed radiation. The study aims to identify key predictors of heart disease within this population, which has a significantly higher risk of developing heart failure compared to the general population. By analyzing data from a large cohort of survivors, the researchers will create tailored algorithms that can better assess and manage cardiovascular risks in these individuals. This approach is designed to enhance early detection and prevention strategies for heart-related issues in African American childhood cancer survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals who have survived childhood cancer and received anthracycline chemotherapy or chest-directed radiation.
Not a fit: Patients who are not African American or who have not undergone anthracycline chemotherapy or chest-directed radiation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and management strategies for heart disease in African American survivors of childhood cancer.
How similar studies have performed: While there have been studies on cardiomyopathy in childhood cancer survivors, this research is novel in its focus on race-specific risk prediction models.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Sapkota, Yadav — St. Jude Children's Research Hospital
- Study coordinator: Sapkota, Yadav
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.