Sponsor or institution
Clinical trials and research at University of Zurich
As of November 12, 2026, Find a Trial lists 112 clinical trials run by University of Zurich that are recruiting, at sites in 12 countries (most in Switzerland (112), Germany (3), Turkey (Türkiye) (2)). 1 was first registered in the last 30 days. By phase: Phase 2 (6), Phase 1/2 (2), Phase 1 (2), Phase 4 (2). There are also 1 NIH-funded research project at this institution, with $717,966 in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 112Clinical trials
- 1NIH research projects
- 1New in 30 days
- 12Countries
Newest trials
All recruiting trials (112)
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Long-term outcomes after vacuum-induced tamponade for postpartum hemorrhage
This study will look at women who had postpartum hemorrhage treated with vacuum-induced tamponade at a Zurich hospital to see how they fared over time, including future pregnancies and fertility.
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Add-on Sildenafil Before Exercise in PAH to See if Max Workload Improves
This study tests whether taking 20 mg sildenafil right before exercise helps people with pulmonary arterial hypertension perform more work during cardiopulmonary testing.
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Fatigue Investigation Using Digital Outcomes
This study tests whether digital monitoring with a smartphone app and wearables can track fatigue in people with MS or long COVID, compared with healthy volunteers.
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Impact of ambient air vs nasal liquid oxygen on exercise performance in pulmonary vascular disease
This study tests whether using nasal liquid oxygen during a 6-minute walk test changes how far patients with PAH or CTEPH can walk compared to breathing room air.
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Liquid oxygen vs ambient air during a 6-minute walk in people with pulmonary vascular disease
This study tests whether walking with liquid oxygen at about 4 L/min helps or hinders distance walked compared with walking on room air in adults with PAH or CTEPH living in Switzerland.
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Daily adjustment of radiation dose in MRI-guided SBRT for abdominal and pelvic tumors
This trial tests whether adjusting the radiation dose in real-time during MRI-guided SBRT improves targeting for abdominal or pelvic tumors.
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Global health study on hidradenitis suppurativa
This study tests how people with hidradenitis suppurativa access care and what treatments they receive across different health systems.
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Global Health Look at Atopic Dermatitis
A worldwide, multicenter study tests how people with atopic dermatitis access care and treat it, using data from routine medical records.
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Global psoriasis care patterns and outcomes (observational)
This study tests how psoriasis is managed across different health systems by following patients over time to see care access, treatments, disease severity, and quality of life.
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Natural cervical ripening to delay pharmacological induction of labor
This pilot study tests whether nipple stimulation and membrane sweeping can help some pregnant people go into labor on their own without needing drugs.
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Hormone and metabolic patterns in hypothalamus-like brain cells from people with anorexia nervosa
This study will test whether hypothalamic-like neurons made from adult women with long-standing anorexia nervosa respond differently to metabolic hormones than neurons from healthy women.
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Sleep, Stress and Migraine — Personalized Sleep and Stress Training
This project tries to see if using a WHOOP wearable and daily app questions to track sleep and stress can identify personal triggers and deliver tailored sleep and stress recommendations to reduce migraine attacks in adults with episodic migraine.
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TUBSIS 2.0 — an online program to help adults reduce or quit smoking and vaping
This program tests whether a free, anonymous, 4-week web-based course using mindfulness, self-compassion, and behavior-change techniques helps German-, English-, and Turkish-speaking adults who smoke or vape reduce or quit tobacco.
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Brain blood flow changes after successful clot removal in acute ischemic stroke
This study will use a special MRI blood-oxygenation breathing test to see if it can detect patients with acute ischemic stroke who do not improve after successful clot removal.
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Sex differences in postoperative delirium and whether family visits help
This study looks to see if a patient’s sex changes the risk of delirium after non-cardiac surgery and whether family visits can help prevent it, especially in adults 65 and older.
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Robotic-assisted versus conventional bronchoscopy for cryobiopsy to diagnose interstitial lung disease
This trial will test whether robotic-assisted bronchoscopy with cone-beam CT finds better biopsy samples than conventional fluoroscopy-guided bronchoscopy in adults who need a lung biopsy for suspected interstitial lung disease.
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How bladder microbes and immune signals affect lower urinary tract health
This project will test whether differences in bladder microbes and immune signals are linked to urinary tract health in adults with and without various urinary conditions.
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Dynamic individualized risk profiling for patients receiving CD19 CAR T-cell therapy
This project tries a combined blood, imaging, and lab test to predict which adults with relapsed or refractory B‑cell lymphoma will do well after CD19 CAR T‑cell therapy.
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Timed smartphone support to boost social connections for people waiting for outpatient psychotherapy
This project tests whether a smartphone-based just-in-time support program can reduce daily depressive symptoms and increase received social support for adults waiting for outpatient psychotherapy.
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Sound-based sleep stimulation to boost brain training in Parkinson's with mild cognitive impairment
This test will see if playing gentle, phase-targeted sounds during sleep together with a five-week home cognitive training program helps people with Parkinson's disease and mild cognitive impairment get more benefit from training.
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How acute low-oxygen levels affect the right side of the heart in asthma
This study tests how short-term exposure to simulated high-altitude oxygen levels affects right heart function in adults with asthma.
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How short-term low oxygen exposure affects the right side of the heart in healthy adults
We test whether short-term reduced oxygen (simulated 2,500 m and 4,000 m) changes right ventricular function in healthy adults at rest and during light exercise.
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Right-heart response to short-term low oxygen in people with past HAPE
This trial tests whether brief exposure to simulated high altitude (low oxygen) changes right-heart function in adults who previously had high-altitude pulmonary edema (HAPE).
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Adding Street Racket to outpatient pulmonary rehabilitation
This project will test whether Street Racket, a simple group racket game, can be added to outpatient pulmonary rehabilitation for adults with chronic lung disease to make sessions more acceptable and engaging.
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Speech-based test to estimate relapse risk in psychosis
This project will try using weekly smartphone speech recordings and short self-reports to see if an automated system can predict relapse risk in people with psychosis.
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Gentle nighttime sounds to boost deep sleep and slow brain changes in iRBD and early Parkinson's
This test will see if playing gentle sounds during sleep can boost deep slow-wave sleep and slow brain changes in people with isolated REM sleep behavior disorder or early Parkinson's disease.
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Geriatric assessment before CAR‑T or bispecific antibody therapy to predict side effects and outcomes in older adults
This study will test whether a brief geriatric assessment done before CAR‑T or bispecific antibody treatment can help predict side effects and outcomes for people aged 65 and older with aggressive lymphoma or multiple myeloma.
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Vortioxetine for newly diagnosed glioblastoma
Aimed at adults with newly diagnosed glioblastoma, this study tests whether the antidepressant vortioxetine can help alongside standard treatment.
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SuperCable vs. steel wires for closing the sternum after heart surgery
This trial tests whether SuperCable sternal closure helps the bone heal faster and reduces pain after heart surgery compared with conventional steel wires in adults undergoing CABG.
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Lung volume changes with synchronized noninvasive ventilator support in preterm infants
This study will use a noninvasive imaging belt to see if synchronized ventilator inflations produce larger lung volumes than unsynchronized or backup inflations in very preterm infants on sNIPPV.
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Reducing masseter (jaw) muscle stiffness with a heat pad or a massage gun
This study will test whether using a commercial heat pad or a commercial massage gun can reduce stiffness of the masseter (jaw) muscle in adults to help guide options for people with TMD.
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Role of the LC-NA System in Sleep Fragmentation
This study tests whether low or high doses of dexmedetomidine can reduce sleep disruption caused by auditory noise in healthy adults.
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Understanding heart failure through detailed patient profiles and molecular profiling
This study tests whether combining clinical data with multi-omics profiling can reveal molecular signatures and non-coding RNAs linked to heart failure in adults.
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PET, MRI and ultrasound to track heart changes in ATTR cardiac amyloidosis
This study will try PET, MRI and ultrasound scans in people with ATTR cardiac amyloidosis starting tafamidis to see if the new images explain why some patients keep getting worse.
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Personalized sleep-based sound stimulation to improve walking in Parkinson's
This project will test whether playing personalized rehabilitation-related sounds during sleep can help people with Parkinson's who have gait and balance problems get more benefit from their rehabilitation.
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Feasibility of MR-Informed Adaptive Marker-less SBRT for Localized Prostate Cancer in Patients with Bilateral Hip Prostheses
This study tests a new MRI-guided, marker-free SBRT approach to treat localized prostate cancer in patients who have bilateral hip replacements.
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Do CaV1.2 calcium channels link 5G exposure to sleep changes?
We will test whether taking nimodipine before 5G exposure can prevent sleep changes in healthy adults who carry a specific CACNA1C gene variant.
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Intralymphatic cat-allergy immunotherapy for people with cat-induced rhinitis and asthma
This trial tests whether three to four ultrasound-guided injections of a cat-allergy vaccine into an inguinal lymph node are safe and trigger helpful immune responses in adults with cat-caused allergic rhinitis, with or without asthma.
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Cryobiopsy for lung cancer lymph nodes
This study is testing a new way to take tissue samples from lymph nodes in lung cancer patients using freezing techniques to see if it gives better results than the usual methods.
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Driving performance when adults with ADHD briefly stop stimulant medication
This will see if short, self-chosen breaks from stimulant ADHD medication change driving-simulator performance in adult drivers with ADHD.
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Balance reactions to moving visual patterns in people with concussion and other dizziness
This project will test whether spinning visual patterns shown on a rotating disk or in virtual reality cause balance problems and dizziness in adults with recent concussion or other ongoing dizziness compared with healthy people.
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Driving-simulator sleepiness test compared with the standard wakefulness test for people with OSA after pausing CPAP
This research will test whether a naturalistic driving-simulator sleepiness test can detect dangerous sleepiness behind the wheel in adults with obstructive sleep apnea after temporarily stopping CPAP treatment.
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Comparing face masks and no masks for head and neck radiation therapy
This study tests whether using a face mask during radiation therapy for head and neck cancer makes patients feel more comfortable and less anxious compared to not using a mask.
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Adaptive radiotherapy for localized prostate cancer
This study is testing a new type of radiation therapy for men with localized prostate cancer who have urinary problems to see if it can safely treat their cancer without causing too many side effects.
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MR-guided daily-adapted stereotactic radiotherapy for ultracentral lung tumours with CBCT delivery
This study tests whether daily MR-based adaptation followed by CBCT-guided SBRT can safely treat adults with ultracentral primary or metastatic lung tumours.
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Measuring the size of hypertrophic scars and keloids using 3D cameras after surgery
This study is testing whether a 3D camera can help measure the size of scars and keloids in patients after surgery to see how they change over time.
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Pharmacoscopy-guided treatment for refractory brain tumors
This trial tests whether personalized drug testing on a patient’s tumor cells can guide treatment choices for adults with hard-to-treat brain cancers like glioblastoma.
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Improving mental health support for refugees through a psychological intervention
This study is testing a new way to help refugees and asylum seekers with their mental health by improving a support program that includes extra sessions and reminders to see if it makes a difference.
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Predicting depression in patients after heart surgery
This study is trying to see if a new tool can help predict which patients might develop depression after heart surgery, so they can get help sooner.
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Precision oncology program for advanced cancer patients
This study is testing a new way to personalize cancer treatment for people with advanced cancer by looking closely at their tumors to see which therapies might work best for them.
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Using ex vivo pharmacoscopy to guide treatment for brain metastases
This project will test whether pharmacoscopy, a lab test that screens a patient's tumor cells against many drugs, can help pick effective treatments for adults having surgery for brain metastases.
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DigiPall: digital symptom and wearable monitoring in palliative care
This project will test whether a wearable that tracks heart rate and steps plus a daily smartphone chatbot that asks about symptoms and gives tips can reduce unplanned hospital readmissions and improve well‑being for people with advanced cancer or other life‑threatening illnesses in palliative care.
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Personalized neurorehabilitation for improving gait in Parkinson's disease
This study is testing a personalized approach to help people with Parkinson's disease improve their walking and balance using tailored feedback and sounds during sleep.
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Comparing two types of wrist movement after ligament reconstruction
This study tests whether starting wrist rehab with a dart-throwing motion or a traditional approach helps people recover better after scapholunate ligament surgery.
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Reducing radiation volume in oropharyngeal cancer treatment
This study is testing a personalized way to reduce radiation for people with oropharyngeal cancer to see if it can lower side effects while still being effective.
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Measuring Eating Behaviors After Bariatric Surgery
This study is trying to see how bariatric surgery changes drinking habits in patients and how those changes relate to weight loss and other health outcomes.
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Breath analysis to detect fungal infections in leukemia patients
This study is testing if analyzing breath samples can help doctors detect fungal infections in leukemia patients who are at high risk due to their treatment.
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Predicting recovery after acute ischemic stroke using neurologists' judgments and AI
This project tests whether neurologists or a deep-learning computer can better predict recovery after an acute ischemic stroke for patients who arrive within 24 hours using routine clinical and imaging data.
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Microclots and neutrophil activation as markers of stroke risk and reperfusion failure
This project tries to see if tiny blood clots and activated neutrophils in blood can predict stroke risk and explain why some people with ischemic stroke don't improve after clot removal.
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Evaluating a new imaging technique for breast cancer detection
This study is testing a new type of mammogram called phase contrast mammography to see if it can better detect breast cancer in women with dense breast tissue compared to regular methods.
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Reducing postpartum blood loss with coagulation factor XIII
This study is testing if giving a treatment called coagulation factor XIII can help reduce heavy bleeding after childbirth in women who have had a vaginal delivery.
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Registry for patients with mastocytosis and hypertryptasemia
This study is collecting information and samples from patients with mastocytosis and high tryptase levels at the University Hospital of Zurich to better understand their conditions and improve treatment.
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Personalized neurorehabilitation for stroke recovery
This study is testing a new personalized rehab approach to help stroke survivors improve their walking by using tailored feedback and sound therapy during sleep.
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Investigating pain mechanisms in patients with spinal cord injuries
This study is trying to understand how spinal cord injuries cause nerve pain by looking at how the body processes pain and responds to it in people with different types of spinal injuries and nerve issues.
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Understanding quality of life and stress in stroke patients and their caregivers
This study looks at how stroke affects the quality of life and stress levels in both patients and their caregivers to see how they compare to people without stroke.
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Assessment of patients with leptomeningeal metastasis
This study is trying to create a standard way to check how patients with leptomeningeal metastases are doing, so doctors can better understand and manage their condition.
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Comparing Propofol and Sevoflurane for Managing Erections During Urological Surgery
This study is testing whether using propofol or sevoflurane as anesthesia during urological surgery affects the chances of having unwanted erections and if it leads to more complications for patients.
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Evaluation of ultra low dose CT scans with Iomeron 400 contrast
This study is testing if using ultra low dose CT scans with a special contrast dye can help find lung problems like blood clots, cancer, and pneumonia while keeping radiation exposure low.
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Using open-label placebos to help reduce opioid use in chronic pain patients
This study is testing whether using open-label placebos can help people with chronic pain reduce their use of opioids like morphine.
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Monitoring health effects of intermittent fasting in obese adults
This study is testing whether two types of intermittent fasting can help obese adults improve their health compared to regular weight-loss counseling.
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Using metreleptin to treat anorexia nervosa
This study is testing if a hormone treatment called metreleptin can help people with anorexia nervosa improve their mood and gain weight.
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Using virtual reality to help dialysis patients feel better
This study is testing if virtual reality sessions during dialysis can help patients feel better both physically and mentally.
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Comparing single-isocenter and multiple-isocenter SBRT for treating multiple metastatic cancers
This study is testing if a simpler radiation treatment for multiple cancers works just as well as a more complex approach to see if it can make things easier and more comfortable for patients.
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Evaluating the effects of PRISMA on mental health in pretrial detainees
This study is testing a new therapy program called PRISMA to see if it can help improve the mental health of people held in pretrial detention.
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Comparing live music therapy to recorded music therapy for terminally ill patients
This study is testing whether live music therapy can help terminally ill patients feel better compared to listening to recorded music.
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Understanding brain changes after congenital upper limb loss
This study looks at how the brains of people born without a hand adapt and change over time compared to those with typical hand function.
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Understanding caregiver stress and bereavement impacts
This study looks at how the stress of caring for a dying spouse and the grief after their loss affects the health of caregivers, to see if we can find better ways to help them cope.
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Examining changes in the central nervous system after spinal cord injury
This study is trying to see how spinal cord injuries affect the brain and nervous system in both new and long-term patients to help improve treatments for recovery.
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Using glutamate inhibitors to treat glioblastoma
This study is testing if adding certain medications that block glutamate can help improve treatment outcomes for people with newly diagnosed glioblastoma when used with standard chemotherapy and radiation.
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Registry of patients with pulmonary hypertension in Switzerland
This study is collecting information from patients with pulmonary hypertension in Switzerland to better understand their experiences and improve treatment options.
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Higher radiation doses for treating recurrent ventricular tachycardia
This study is testing if higher doses of targeted radiation can help people with recurrent ventricular tachycardia who haven't had success with other treatments.
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Noninvasive detection of lung transplant dysfunction using breath tests
This study is testing a breath test to see if it can help find early signs of lung transplant rejection in patients three months after their surgery.
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Assessing glioblastoma response during MR-guided radiation therapy
This study is testing how well glioblastoma responds to radiation therapy by using weekly MRI scans to track changes in the tumor for 20 patients.
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Monitoring depression symptoms during therapy using mobile technology
This study tests if using a smartphone to track depression symptoms during therapy can help people with mild to moderate depression feel better compared to regular therapy alone.
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7T MRI scans for migraine, visual snow, and epilepsy
This project will use high-field 7T MRI to try to find microstructural and network differences in people with migraine, visual snow, or drug‑resistant epilepsy and in healthy volunteers.
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Analyzing exhaled breath to distinguish lung and airway diseases
This study is testing if analyzing the breath of people with lung and airway diseases can help tell the difference between conditions like COPD and asthma.
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Analyzing exhaled breath patterns in patients with pulmonary diseases
This study is trying to see how breathing patterns change in adults with obstructive sleep apnea or other lung diseases after taking medication.
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Evaluation of a male-specific psychotherapeutic program for depression
This study is testing a new therapy program designed specifically for men with depression to see if it works better than standard therapy.
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Comparing soft tissue augmentation methods for treating peri-implantitis
This study is testing whether using a special collagen matrix or a tissue graft can help people with moderate to severe peri-implantitis heal better when combined with other treatments compared to those who don’t receive any soft tissue help.
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Eccentric (braking) cycling instead of regular pedaling for people with left heart failure
This will try short sessions of eccentric (braking) cycling versus regular cycling in people with left-heart failure to see if it builds leg muscle and fitness while using less oxygen and putting less strain on the heart.
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Comparing Acceptance Commitment Therapy and Micro Breaks for Chronic Fatigue Syndrome
This study is testing whether Acceptance Commitment Therapy or short breaks can help people with Chronic Fatigue Syndrome feel better and improve their daily lives.
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Comparing blood-flow restricted exercise to traditional exercise for COPD patients
This study tests if exercising with blood-flow restriction can help people with COPD improve their strength and breathing better than traditional exercise.
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Assessing kidney blood flow changes after closing a fistula in transplant patients
This study is testing how closing a fistula affects blood flow in the kidneys of kidney transplant patients to see if it impacts their kidney function.
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Understanding how the reticulospinal system controls movement
This study is testing how a part of the nervous system helps people with spinal cord injuries move by using surprising sounds to see how quickly they can react and move.
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EMDR treatment for PTSD after heart events
This study is testing if EMDR therapy can help people with PTSD after heart events feel better and reduce their risk of future heart problems.
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Observing brain blood flow changes in neurosurgical patients
This study looks at how blood flow in the brain changes over time in neurosurgery patients compared to those who don’t have surgery and healthy people, to see if these changes can help us understand brain health better.
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Comparing lung surgery and bronchoscopic treatment for severe emphysema
This study is testing whether lung surgery or a less invasive bronchoscopic treatment works better for people with severe emphysema.
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Evaluating outcomes of flexor tendon injury treatments
This study is looking at how well different treatments for finger and thumb tendon injuries work by tracking recovery and therapy results from patients over several years.
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Long-term observation of atopic dermatitis and related allergic conditions
This project will collect medical and lab data over time to see which genetic, immune, environmental, and microbial factors relate to the course or remission of atopic dermatitis and other atopic diseases in people of all ages.
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Understanding brain changes after stroke
This study looks at how a stroke affects the brain and spinal cord in patients compared to healthy people to see what changes happen and how they relate to recovery.
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Using nerve stimulation to improve bladder function in acute spinal cord injury
This study is testing whether a nerve stimulation treatment can help people with recent spinal cord injuries improve their bladder function and avoid related problems.
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Long-term follow-up of individuals seeking HIV prevention in Switzerland
This study follows people in Switzerland who are using a medication to prevent HIV to see how well it works and to check for any sexually transmitted infections over three years.
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Understanding CNS Changes After Spinal Cord Injury
This study looks at how the brain and nervous system change after a spinal cord injury to see if these changes can help predict recovery and understand symptoms better.
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Understanding the causes of primary immune deficiencies
This study looks at the causes of primary immune deficiencies to see how they affect the body's ability to fight infections and inflammation, with hopes of creating better treatments for those affected.
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Using oral propranolol to prevent severe eye disease in premature infants
This study is testing if giving oral propranolol to extremely premature infants can help prevent severe eye disease that could lead to blindness.
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Deep brain stimulation to improve walking in patients with incomplete spinal cord injury
This study is testing if a new brain stimulation treatment can help people with incomplete spinal cord injuries walk better and improve their quality of life.
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Examining MRI changes in spinal cord disorders
This study looks at how changes in the spinal cord and fluid around it can help us understand spinal cord disorders better and improve early diagnosis and treatment for patients.
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Observational study on spinal cord injury recovery in Europe
This study is trying to understand how people recover from spinal cord injuries by collecting information from patients in Europe who have recently experienced these injuries.
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Database for patients with lower urinary tract dysfunction due to neurological issues
This study is collecting information from people with bladder problems caused by neurological issues to see how to better manage their symptoms and improve their quality of life.
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Observational study of transplanted individuals in Switzerland
This study is looking at people in Switzerland who have received organ or stem cell transplants to see how their health and well-being are affected over time.
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Observational study on patients with non-alcoholic fatty liver disease
This study is looking at liver tissue from people with non-alcoholic fatty liver disease to see how certain body signals relate to weight gain and insulin resistance over time.
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Understanding early HIV infections in Zurich
This study looks at how early HIV infections affect people's health and how starting treatment right away can change the course of the disease for those newly diagnosed in Zurich.
NIH-funded research (1)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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HIV drug resistance in people on dolutegravir-based HIV therapy across many countries
This grant studies how HIV may become resistant to dolutegravir-based treatment in people who are not responding well to therapy, across many countries and groups including children.
Quick answers
How many clinical trials run by University of Zurich are recruiting right now?
112, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 12 countries. The most sites are in Switzerland (112 trials), Germany (3 trials), Turkey (Türkiye) (2 trials), Czechia (2 trials), Netherlands (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 6, Phase 1/2: 2, Phase 1: 2, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.