Noninvasive detection of lung transplant dysfunction using breath tests

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to detect chronic rejection, known as bronchiolitis obliterans syndrome (BOS), in lung transplant recipients through a noninvasive method called Multiple Breath Washout (MBW) tests. By measuring lung clearance index (LCI) three months post-transplant, the study seeks to identify early signs of BOS, which is a leading cause of mortality after the first year of transplantation. Early detection may allow for timely treatment adjustments to improve patient outcomes. Approximately 90 participants from Zurich University Hospital will be involved in this assessment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All recipients who underwent bilateral lung transplantation at Zurich University Hospital will be included.

Exclusion Criteria:

* Retransplantation

Where it's running

• University Hospital Zurich
  Zurich, Switzerland Recruiting

Study contacts

• Principal investigator: Carolin Steinack, MD — University of Zurich
• Study coordinator: Carolin Steinack, MD
• Email: carolin.steinack@usz.ch
• Phone: 0041442551111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.