Home › Trials › NCT03893188
Clinical trial Recruiting at 40 sites Observational Ages 16 to 120

Long-term follow-up of individuals seeking HIV prevention in Switzerland

Official title: A Multicenter, Observational Cohort to Study the Characteristics of Individuals Asking for Pre-exposure Prophylaxis (PrEP) and the Incidence of HIV and Other Sexually Transmitted Infections: 'The SwissPrEPared Study'

Run by University of Zurich · NCT03893188 · Data updated 2026-11-12

This study follows people in Switzerland who are using a medication to prevent HIV to see how well it works and to check for any sexually transmitted infections over three years.

Quick facts

Study typeObservational
Ages16 Years to 120 Years
SexAll
Enrollment3000 (estimated)
SponsorUniversity of Zurich
Academic / other
Locations41 sites (Aarau, Canton of Aargau and 40 other locations)
StatusRecruiting
StartedApril 10, 2019
Main results expectedMarch 2030
Study endsMarch 2030
Registry record updatedApril 6, 2023
Trial IDNCT03893188 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 16 and older who are HIV negative and seeking PrEP prescription.

Probably not a fit

Patients who are unable to follow program procedures due to language barriers or mental health issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The SwissPrEPared Study is a large, multicentric cohort study that aims to follow individuals requesting pre-exposure prophylaxis (PrEP) for HIV over a period of three years. It seeks to gather epidemiological data on PrEP usage in Switzerland and monitor the occurrence of sexually transmitted infections (STIs) among this population. Additionally, the study will assess sexual health and well-being through a specially designed questionnaire. This observational study is nested within the broader SwissPrEPared Program.

Why it matters

Potential benefit: If successful, this study could enhance understanding of PrEP usage and improve sexual health outcomes for individuals at risk of HIV.

How similar studies have gone: Other studies on PrEP have shown success in improving HIV prevention strategies, indicating that this approach is supported by previous findings.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Participation in the SwissPrEPared program
* Aged ≥16 years
* HIV negative

Exclusion Criteria:

* Individuals unable to follow program procedures (e.g. language barriers, mental or psychiatric disorders)

Where it's running

  • Kantonsspital Aarau
    Aarau, Canton of Aargau, Switzerland     Recruiting
  • Kantonsspital Baden
    Baden, Canton of Aargau, Switzerland     Recruiting
  • MedCenter Volta
    Basel, Canton of Basel-City, Switzerland     Recruiting
  • Praxis Hammer
    Basel, Canton of Basel-City, Switzerland     Recruiting
  • Praxis dr. med. Clara Thierfelder
    Basel, Canton of Basel-City, Switzerland     Recruiting
  • University Hospital Basel
    Basel, Canton of Basel-City, Switzerland     Recruiting
Show 35 more locations
  • Spitalzentrum Biel - Centre hospitalier Bienne
    Biel/Bienne, Canton of Bern, Switzerland     Recruiting
  • Spital Thun
    Thun, Canton of Bern, Switzerland     Recruiting
  • Médecine Interne/Infectiologie FMH
    Cottens, Canton of Fribourg, Switzerland     Recruiting
  • Hôpital du Jura
    Delémont, Canton of Jura, Switzerland     Recruiting
  • Kantonsspital Olten
    Olten, Canton of Solothurn, Switzerland     Recruiting
  • Medical and Therapeutic Centre La Lignière
    Gland, Canton of Vaud, Switzerland     Recruiting
  • Cabinet Dr. Erika Castro Batänjer
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • Cabinet Gare 10
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • Cabinet Rumine 35
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • Cabinet Rumine 9
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • University Hospital Laussane
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • Checkpoint Lausanne
    Lausanne, Canton of Vaud, Switzerland     Recruiting
  • Fondation PROFA
    Renens VD, Canton of Vaud, Switzerland     Recruiting
  • Kantonsspital Winterthur
    Winterthur, Canton of Zurich, Switzerland     Recruiting
  • Kantonsspital Graubünden
    Chur, Kanton Graubünden, Switzerland     Recruiting
  • Kantonsspital Münsterlingen
    Münsterlingen, Thurgau, Switzerland     Recruiting
  • Kantonsspital Ticcino
    Lugano, Ticcino, Switzerland     Recruiting
  • Checkpoint Bern
    Bern, Switzerland     Recruiting
  • University Hospital Bern
    Bern, Switzerland     Recruiting
  • Cabinet Dr. Marta Buzzi
    Geneva, Switzerland     Recruiting
  • Praxis Emmanuelle Boffi
    Geneva, Switzerland     Recruiting
  • University Hospital Geneva
    Geneva, Switzerland     Recruiting
  • Cabinet Malagnou 2
    Geneva, Switzerland     Recruiting
  • Checkpoint Geneva
    Geneva, Switzerland     Recruiting
  • Maihofpraxis
    Lucerne, Switzerland     Recruiting
  • Réseau Hospitalier Neuchâtelois
    Neuchâtel, Switzerland     Recruiting
  • Kantonspital St. Gallen
    Sankt Gallen, Switzerland     Recruiting
  • Arud
    Zurich, Switzerland     Recruiting
  • Praxis Kalkbreite
    Zurich, Switzerland     Recruiting
  • Checkpoint Zürich
    Zurich, Switzerland     Recruiting
  • Dermatologisches Zentrum Zürich AG
    Zurich, Switzerland     Recruiting
  • Praxisgemeinschaft D29
    Zurich, Switzerland     Recruiting
  • Stadtspital Triemli
    Zurich, Switzerland     Recruiting
  • Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich
    Zurich, Switzerland     Recruiting
  • Travel Clinic UZH
    Zurich, Switzerland     Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • California MEPS Hub for HIV prevention and reentry support

    This project will test a peer-led, app-based program with small cash incentives to help people with substance use recently released from jail or prison get PrEP, HIV/STI testing, and related services.

    Recruiting at 3 sites University of California, Los Angeles · Oakland, California and 2 other locations · NCT07433985

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov ↗ Find more trials like this →
Browse more
University of Zurich 113
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.