Long-term follow-up of individuals seeking HIV prevention in Switzerland
A Multicenter, Observational Cohort to Study the Characteristics of Individuals Asking for Pre-exposure Prophylaxis (PrEP) and the Incidence of HIV and Other Sexually Transmitted Infections: 'The SwissPrEPared Study'
This study follows people in Switzerland who are using a medication to prevent HIV to see how well it works and to check for any sexually transmitted infections over three years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 16 Years to 120 Years |
| Sex | All |
| Sponsor | University of Zurich Academic / other |
| Locations | 41 sites (Aarau, Canton of Aargau and 40 other locations) |
| Trial ID | NCT03893188 on ClinicalTrials.gov |
What this trial studies
The SwissPrEPared Study is a large, multicentric cohort study that aims to follow individuals requesting pre-exposure prophylaxis (PrEP) for HIV over a period of three years. It seeks to gather epidemiological data on PrEP usage in Switzerland and monitor the occurrence of sexually transmitted infections (STIs) among this population. Additionally, the study will assess sexual health and well-being through a specially designed questionnaire. This observational study is nested within the broader SwissPrEPared Program.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 16 and older who are HIV negative and seeking PrEP prescription.
Not a fit: Patients who are unable to follow program procedures due to language barriers or mental health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of PrEP usage and improve sexual health outcomes for individuals at risk of HIV.
How similar studies have performed: Other studies on PrEP have shown success in improving HIV prevention strategies, indicating that this approach is supported by previous findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participation in the SwissPrEPared program * Aged ≥16 years * HIV negative Exclusion Criteria: * Individuals unable to follow program procedures (e.g. language barriers, mental or psychiatric disorders)
Where this trial is running
Aarau, Canton of Aargau and 40 other locations
- Kantonsspital Aarau — Aarau, Canton of Aargau, Switzerland (Recruiting)
- Kantonsspital Baden — Baden, Canton of Aargau, Switzerland (Recruiting)
- MedCenter Volta — Basel, Canton of Basel-City, Switzerland (Recruiting)
- Praxis Hammer — Basel, Canton of Basel-City, Switzerland (Recruiting)
- Praxis dr. med. Clara Thierfelder — Basel, Canton of Basel-City, Switzerland (Recruiting)
- University Hospital Basel — Basel, Canton of Basel-City, Switzerland (Recruiting)
- Spitalzentrum Biel - Centre hospitalier Bienne — Biel/Bienne, Canton of Bern, Switzerland (Recruiting)
- Spital Thun — Thun, Canton of Bern, Switzerland (Recruiting)
- Médecine Interne/Infectiologie FMH — Cottens, Canton of Fribourg, Switzerland (Recruiting)
- Hôpital du Jura — Delémont, Canton of Jura, Switzerland (Recruiting)
- Kantonsspital Olten — Olten, Canton of Solothurn, Switzerland (Recruiting)
- Medical and Therapeutic Centre La Lignière — Gland, Canton of Vaud, Switzerland (Recruiting)
- Cabinet Dr. Erika Castro Batänjer — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- Cabinet Gare 10 — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- Cabinet Rumine 35 — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- Cabinet Rumine 9 — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- University Hospital Laussane — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- Checkpoint Lausanne — Lausanne, Canton of Vaud, Switzerland (Recruiting)
- Fondation PROFA — Renens VD, Canton of Vaud, Switzerland (Recruiting)
- Kantonsspital Winterthur — Winterthur, Canton of Zurich, Switzerland (Recruiting)
- Kantonsspital Graubünden — Chur, Kanton Graubünden, Switzerland (Recruiting)
- Kantonsspital Münsterlingen — Münsterlingen, Thurgau, Switzerland (Recruiting)
- Kantonsspital Ticcino — Lugano, Ticcino, Switzerland (Recruiting)
- Checkpoint Bern — Bern, Switzerland (Recruiting)
- University Hospital Bern — Bern, Switzerland (Recruiting)
- Cabinet Dr. Marta Buzzi — Geneva, Switzerland (Recruiting)
- Praxis Emmanuelle Boffi — Geneva, Switzerland (Recruiting)
- University Hospital Geneva — Geneva, Switzerland (Recruiting)
- Cabinet Malagnou 2 — Geneva, Switzerland (Recruiting)
- Checkpoint Geneva — Geneva, Switzerland (Recruiting)
- Maihofpraxis — Lucerne, Switzerland (Recruiting)
- Réseau Hospitalier Neuchâtelois — Neuchâtel, Switzerland (Recruiting)
- Kantonspital St. Gallen — Sankt Gallen, Switzerland (Recruiting)
- Arud — Zurich, Switzerland (Recruiting)
- Travel Clinic UZH — Zurich, Switzerland (Not_yet_recruiting)
- Praxis Kalkbreite — Zurich, Switzerland (Recruiting)
- Checkpoint Zürich — Zurich, Switzerland (Recruiting)
- Dermatologisches Zentrum Zürich AG — Zurich, Switzerland (Recruiting)
- Praxisgemeinschaft D29 — Zurich, Switzerland (Recruiting)
- Stadtspital Triemli — Zurich, Switzerland (Recruiting)
- Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich — Zurich, Switzerland (Recruiting)
Study contacts
- Principal investigator: Benjamin Hampel, MD — University of Zurich
- Study coordinator: Jan Fehr, Prof.
- Email: jan.fehr@usz.ch
- Phone: +41 44 634 46 11
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.