Evaluating outcomes of flexor tendon injury treatments
Outcomes of Flexor Tendons Repair in Zones I-III From 2014-2025: a Swiss Multicenter Cohort Study
University of Zurich · NCT04312412
This study is looking at how well different treatments for finger and thumb tendon injuries work by tracking recovery and therapy results from patients over several years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | University of Zurich (other) |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Trial ID | NCT04312412 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect and analyze data from multiple centers regarding the outcomes of flexor tendon repairs in the fingers and thumb. It utilizes a controlled active motion (CAM) protocol post-surgery to assess recovery and rehabilitation. The study will measure surgical and therapy outcomes while evaluating various factors that may influence these results. Data will be gathered from patients treated between 2014 and 2025 to ensure a comprehensive understanding of treatment effectiveness.
Who should consider this trial
Good fit: Ideal candidates include individuals who have sustained flexor tendon injuries in the fingers or thumb between 2014 and 2025.
Not a fit: Patients with concomitant injuries, such as fractures or large soft tissue injuries, or those with basic diseases like rheumatoid diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for flexor tendon injuries, enhancing recovery outcomes for patients.
How similar studies have performed: While this approach is based on established practices, the multicenter data collection aspect may provide novel insights into treatment outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Injury between 2014 and 2025 * Flexor tendon injury of the fingers or thumb in zones 1-3 Exclusion Criteria: * No given consent * Concomitant injuries as fractures, large soft tissue injuries, replantation * Bony avulsion fracture of flexor tendon (Jersey finger) * Basic disease as rheumatoid diseases * Primary and secondary tendon reconstruction and tendon transfer
Where this trial is running
Zurich, Canton of Zurich
- University Hospital Zurich, Clinic of Reconstructive Surgery — Zurich, Canton of Zurich, Switzerland (RECRUITING)
Study contacts
- Principal investigator: Maurizio Calcagni, PD Dr. med. — University of Zurich
- Study coordinator: Vera Beckmann-Fries
- Email: vera.beckmann-fries@usz.ch
- Phone: +41 44 255 51 24
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Finger Injuries, Tendon Injury - Hand, tendon injuries, flexor tendons