Evaluating outcomes of flexor tendon injury treatments
Official title: Outcomes of Flexor Tendons Repair in Zones I-III From 2014-2025: a Swiss Multicenter Cohort Study
Run by University of Zurich · NCT04312412 · Data updated 2026-11-12
This study is looking at how well different treatments for finger and thumb tendon injuries work by tracking recovery and therapy results from patients over several years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Status | Recruiting |
| Started | January 1, 2014 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | December 13, 2021 |
| Trial ID | NCT04312412 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals who have sustained flexor tendon injuries in the fingers or thumb between 2014 and 2025.
✕Probably not a fit
Patients with concomitant injuries, such as fractures or large soft tissue injuries, or those with basic diseases like rheumatoid diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to collect and analyze data from multiple centers regarding the outcomes of flexor tendon repairs in the fingers and thumb. It utilizes a controlled active motion (CAM) protocol post-surgery to assess recovery and rehabilitation. The study will measure surgical and therapy outcomes while evaluating various factors that may influence these results. Data will be gathered from patients treated between 2014 and 2025 to ensure a comprehensive understanding of treatment effectiveness.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for flexor tendon injuries, enhancing recovery outcomes for patients.
How similar studies have gone: While this approach is based on established practices, the multicenter data collection aspect may provide novel insights into treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Injury between 2014 and 2025 * Flexor tendon injury of the fingers or thumb in zones 1-3 Exclusion Criteria: * No given consent * Concomitant injuries as fractures, large soft tissue injuries, replantation * Bony avulsion fracture of flexor tendon (Jersey finger) * Basic disease as rheumatoid diseases * Primary and secondary tendon reconstruction and tendon transfer
Where it's running
-
University Hospital Zurich, Clinic of Reconstructive Surgery
Zurich, Canton of Zurich, Switzerland Recruiting
Study contacts
- Principal investigator: Maurizio Calcagni, PD Dr. med. — University of Zurich
- Study coordinator: Vera Beckmann-Fries
- Email: vera.beckmann-fries@usz.ch
- Phone: +41 44 255 51 24
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Wrist position in a 3D-printed dorsal blocking splint after flexor tendon repair
This trial tests whether three wrist angles (30° extension, neutral, or 30° flexion) in a 3D-printed dorsal blocking orthosis affect recovery after zone I–II flexor tendon repair in adults.
-
Extracorporeal shock wave therapy after flexor tendon repair in the hand
This will test whether adding extracorporeal shock wave therapy to standard rehabilitation helps people 8–12 weeks after flexor tendon repair in the hand regain motion, reduce pain, and improve grip and dexterity.
-
Surgery or semi-occlusive dressing for a single finger amputation
This study will test whether a semi-occlusive film dressing or surgery gives better hand function for adults who have lost the tip of a single finger.
-
Virtual reality rehab with early active mobilization after flexor tendon repair
This study tests whether adding virtual reality–based rehabilitation to an early active mobilization plan helps people recover finger movement, strength, and less pain after flexor tendon repair.
-
Rehabilitation comparison after thumb flexor tendon repair
This tests whether starting early active motion or keeping the thumb in a plaster cast for four weeks works better after surgery for a torn thumb flexor tendon in people older than 15.
-
Using Medrol Dosepak to Lower Opioid Use After Foot and Ankle Surgery
This study is testing if a short course of a steroid medication can help people manage pain and use fewer opioids after foot and ankle surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.