Analyzing exhaled breath patterns in patients with pulmonary diseases
Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry (SESI-MS) in Human Subjects
University of Zurich · NCT05456009
This study is trying to see how breathing patterns change in adults with obstructive sleep apnea or other lung diseases after taking medication.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Zurich (other) |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Trial ID | NCT05456009 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on identifying exhaled breath patterns in human subjects, particularly those with obstructive sleep apnea (OSA) or other pulmonary diseases. Utilizing mass spectrometry, the study aims to analyze breath samples in a non-invasive manner to gather data on how medication intake affects these patterns. The research will involve adult participants who provide informed consent, with specific exclusion criteria for certain subgroups. The findings could enhance understanding of respiratory conditions and their management.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with obstructive sleep apnea or other pulmonary diseases.
Not a fit: Patients who are under 18 years old or unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for pulmonary diseases based on breath analysis.
How similar studies have performed: While breath analysis is a growing field, this specific approach using mass spectrometry in the context of OSA and pulmonary diseases is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>= 18 years * Informed consent Exclusion Criteria: * specific exclusion criteria for different subgroups
Where this trial is running
Zurich, Canton of Zurich
- University Hospital Zurich — Zurich, Canton of Zurich, Switzerland (RECRUITING)
Study contacts
- Study coordinator: Malcolm Kohler, MD
- Email: malcolm.kohler@usz.ch
- Phone: +41442551111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Exhaled Breath Pattern After Medication Intake, in OSA Patients, or Other Pulmonary Diseases