Analyzing exhaled breath patterns in patients with pulmonary diseases
Official title: Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry (SESI-MS) in Human Subjects
Run by University of Zurich · NCT05456009 · Data updated 2026-11-12
This study is trying to see how breathing patterns change in adults with obstructive sleep apnea or other lung diseases after taking medication.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Status | Recruiting |
| Started | February 19, 2019 |
| Main results expected | March 1, 2030 |
| Study ends | March 1, 2030 |
| Registry record updated | May 29, 2026 |
| Trial ID | NCT05456009 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with obstructive sleep apnea or other pulmonary diseases.
✕Probably not a fit
Patients who are under 18 years old or unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on identifying exhaled breath patterns in human subjects, particularly those with obstructive sleep apnea (OSA) or other pulmonary diseases. Utilizing mass spectrometry, the study aims to analyze breath samples in a non-invasive manner to gather data on how medication intake affects these patterns. The research will involve adult participants who provide informed consent, with specific exclusion criteria for certain subgroups. The findings could enhance understanding of respiratory conditions and their management.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for pulmonary diseases based on breath analysis.
How similar studies have gone: While breath analysis is a growing field, this specific approach using mass spectrometry in the context of OSA and pulmonary diseases is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>= 18 years * Informed consent Exclusion Criteria: * specific exclusion criteria for different subgroups
Where it's running
-
University Hospital Zurich
Zurich, Canton of Zurich, Switzerland Recruiting
Study contacts
- Study coordinator: Malcolm Kohler, MD
- Email: malcolm.kohler@usz.ch
- Phone: +41442551111
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.